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Search Results (4,052)

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Keywords = magnetic responsive

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19 pages, 4169 KiB  
Article
Magnetic Coil’s Performance Optimization with Nonsmooth Search Algorithms
by Igor Reznichenko, Primož Podržaj and Aljoša Peperko
Mathematics 2025, 13(15), 2490; https://doi.org/10.3390/math13152490 (registering DOI) - 2 Aug 2025
Abstract
This research is concerned with design optimization of control systems. Our case study deals with magnetic levitation, in which an essential part is a solenoid. Its dimensions, along with controller parameters, form the optimization variables. We present a novel way of writing the [...] Read more.
This research is concerned with design optimization of control systems. Our case study deals with magnetic levitation, in which an essential part is a solenoid. Its dimensions, along with controller parameters, form the optimization variables. We present a novel way of writing the explicit expression of the solenoid’s force acting on a magnetic dipole, as well as its first derivatives. Numerical tests using non-gradient search algorithms show the difference in optimal designs provided by these methods. Since such optimization depends on output signals, a comparison of step response analysis methods is presented. Full article
(This article belongs to the Special Issue Advances in Metaheuristic Optimization Algorithms)
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16 pages, 2028 KiB  
Article
A Hybrid Algorithm for PMLSM Force Ripple Suppression Based on Mechanism Model and Data Model
by Yunlong Yi, Sheng Ma, Bo Zhang and Wei Feng
Energies 2025, 18(15), 4101; https://doi.org/10.3390/en18154101 (registering DOI) - 1 Aug 2025
Abstract
The force ripple of a permanent magnet synchronous linear motor (PMSLM) caused by multi-source disturbances in practical applications seriously restricts its high-precision motion control performance. The traditional single-mechanism model has difficulty fully characterizing the nonlinear disturbance factors, while the data-driven method has real-time [...] Read more.
The force ripple of a permanent magnet synchronous linear motor (PMSLM) caused by multi-source disturbances in practical applications seriously restricts its high-precision motion control performance. The traditional single-mechanism model has difficulty fully characterizing the nonlinear disturbance factors, while the data-driven method has real-time limitations. Therefore, this paper proposes a hybrid modeling framework that integrates the physical mechanism and measured data and realizes the dynamic compensation of the force ripple by constructing a collaborative suppression algorithm. At the mechanistic level, based on electromagnetic field theory and the virtual displacement principle, an analytical model of the core disturbance terms such as the cogging effect and the end effect is established. At the data level, the acceleration sensor is used to collect the dynamic response signal in real time, and the data-driven ripple residual model is constructed by combining frequency domain analysis and parameter fitting. In order to verify the effectiveness of the algorithm, a hardware and software experimental platform including a multi-core processor, high-precision current loop controller, real-time data acquisition module, and motion control unit is built to realize the online calculation and closed-loop injection of the hybrid compensation current. Experiments show that the hybrid framework effectively compensates the unmodeled disturbance through the data model while maintaining the physical interpretability of the mechanistic model, which provides a new idea for motor performance optimization under complex working conditions. Full article
15 pages, 611 KiB  
Article
Mapping the Mind: Gray Matter Signatures of Personality Pathology in Female Adolescent Anorexia Nervosa Persist Through Treatment
by Lukas Lenhart, Manuela Gander, Ruth Steiger, Agnieszka Dabkowska-Mika, Malik Galijasevic, Stephanie Mangesius, Martin Fuchs, Kathrin Sevecke and Elke R. Gizewski
J. Clin. Med. 2025, 14(15), 5438; https://doi.org/10.3390/jcm14155438 (registering DOI) - 1 Aug 2025
Abstract
Background: Comorbid personality disorders (PDs) in patients with anorexia nervosa (AN) are associated with increased psychopathology, higher suicide risk, and poorer treatment response and outcomes. This study aimed to examine associations between gray matter (GM) volume and PDs in female adolescents with [...] Read more.
Background: Comorbid personality disorders (PDs) in patients with anorexia nervosa (AN) are associated with increased psychopathology, higher suicide risk, and poorer treatment response and outcomes. This study aimed to examine associations between gray matter (GM) volume and PDs in female adolescents with AN before and after short-term psychotherapeutic and nutritional therapy. Methods: Eighteen female adolescents with acute AN, mean age 15.9 years, underwent 3T magnetic resonance imaging before and after weight restoration. The average interval between scans was 2.6 months. Structural brain changes were analyzed using voxel-based morphometry. PDs were assessed using the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID II) and the Assessment of Identity Development Questionnaire. Results: SCID-II total scores showed significant positive associations with GM volume in the mid-cingulate cortex at both time points and in the left superior parietal–occipital lobule at baseline. The histrionic subscale correlated with GM volume in the thalamus bilaterally and the left superior parietal–occipital lobule in both assessments, as well as with the mid-cingulate cortex at follow-up. Borderline and antisocial subscales were associated with GM volume in the thalamus bilaterally at baseline and in the right mid-cingulate cortex at follow-up. Conclusions: PDs in female adolescent patients with AN may be specifically related to GM alterations in the thalamus, cingulate, and parieto-occipital regions, which are present during acute illness and persist after weight restoration therapy. Full article
(This article belongs to the Section Mental Health)
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19 pages, 4726 KiB  
Article
Modeling and Adaptive Neural Control of a Wheeled Climbing Robot for Obstacle-Crossing
by Hongbo Fan, Shiqiang Zhu, Cheng Wang and Wei Song
Machines 2025, 13(8), 674; https://doi.org/10.3390/machines13080674 (registering DOI) - 1 Aug 2025
Abstract
The dynamic model of a wheeled wall-climbing robot exhibits stage-specific changes when traversing different types of obstacles and during various stages of obstacle negotiation. Previous studies often employed remote control methods for obstacle-crossing control, which fail to dynamically adjust the torque distribution of [...] Read more.
The dynamic model of a wheeled wall-climbing robot exhibits stage-specific changes when traversing different types of obstacles and during various stages of obstacle negotiation. Previous studies often employed remote control methods for obstacle-crossing control, which fail to dynamically adjust the torque distribution of magnetic wheels in response to real-time changes in the dynamic model. This limitation makes it challenging to precisely control the robot’s speed and attitude angles during the obstacle-crossing process. To address this issue, this paper first establishes a staged dynamic model for the wall-climbing robot under typical obstacle-crossing scenarios, including steps, 90° concave corners, 90° convex corners, and thin plates. Secondly, an adaptive controller based on a radial basis function neural network (RBFNN) is designed to effectively compensate for variations and uncertainties during the obstacle-crossing process. Finally, comparative simulations and physical experiments demonstrate the effectiveness of the proposed method. The experimental results show that this method can quickly respond to the dynamic changes in the model and accurately track the trajectory, thereby improving the control precision and stability during the obstacle-crossing process. Full article
(This article belongs to the Section Robotics, Mechatronics and Intelligent Machines)
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18 pages, 6130 KiB  
Article
Multi-Objective Optimization Design of Bearingless Interior Permanent Magnet Synchronous Motor Based on MOWOA
by Jianan Wang, Yizhou Hua, Boyan Xu and Yuchen Zhu
Electronics 2025, 14(15), 3080; https://doi.org/10.3390/electronics14153080 (registering DOI) - 31 Jul 2025
Abstract
Bearingless interior permanent magnet synchronous motors (BIPMSMs) have received considerable attention in recent research due to their advantages of high speed, high power density, and absence of mechanical wear. In order to improve the torque and suspension performance of the BIPMSM, an optimization [...] Read more.
Bearingless interior permanent magnet synchronous motors (BIPMSMs) have received considerable attention in recent research due to their advantages of high speed, high power density, and absence of mechanical wear. In order to improve the torque and suspension performance of the BIPMSM, an optimization design method of BIPMSM is proposed in this paper based on sensitivity analysis, response surface fitting, and the multi-objective whale optimization algorithm (MOWOA). Firstly, the structure and operation principle of the BIPMSM are introduced. Secondly, significant variables are extracted based on sensitivity analysis. Then, regression equations of the significant variables and optimization objectives are fitted by the response surface method, and global optimization is performed with MOWOA. Finally, the motor performance before and after optimization is compared. The results demonstrate that the proposed multi-objective optimization design scheme can significantly improve the performance of the BIPMSM and effectively shorten the design cycle. Full article
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21 pages, 5343 KiB  
Article
Multifaceted Analysis of Pr2Fe16.75Ni0.25 Intermetallic Compound: Crystallographic Insights, Critical Phenomena, and Thermomagnetic Behavior Near Room Temperature
by Jihed Horcheni, Hamdi Jaballah, Sirine Gharbi, Essebti Dhahri and Lotfi Bessais
Magnetochemistry 2025, 11(8), 65; https://doi.org/10.3390/magnetochemistry11080065 (registering DOI) - 31 Jul 2025
Abstract
The alloy Pr2Fe16.75Ni0.25 has been examined to investigate its structural properties, critical behavior, and magnetocaloric effects. Rietveld’s refinement of X-ray diffraction patterns has revealed a rhombohedral structure with an R3¯m space [...] Read more.
The alloy Pr2Fe16.75Ni0.25 has been examined to investigate its structural properties, critical behavior, and magnetocaloric effects. Rietveld’s refinement of X-ray diffraction patterns has revealed a rhombohedral structure with an R3¯m space group. Pr2Fe16.9Ni0.25 also demonstrates a direct magnetocaloric effect near room temperature, accompanied by a moderate magnetic entropy change (ΔSMmax = 5.5 J kg1 K1 at μ0ΔH=5 T) and a broad working temperature range. Furthermore, the Relative Cooling Power (RCP) is approximately 89% of the widely recognized gadolinium (Gd) for μ0ΔH=2 T. This compound exhibits a commendable magnetocaloric response, on par with or even surpassing that of numerous other intermetallic alloys. Critical behavior was analyzed using thermo-magnetic measurements, employing methods such as the modified Arrott plot, critical isotherm analysis, and Kouvel-Fisher techniques. The obtained critical exponents (β, γ, and δ) exhibit similarities to those of the 3D-Ising model, characterized explicitly by intermediate range interactions. Full article
40 pages, 18911 KiB  
Article
Twin-AI: Intelligent Barrier Eddy Current Separator with Digital Twin and AI Integration
by Shohreh Kia, Johannes B. Mayer, Erik Westphal and Benjamin Leiding
Sensors 2025, 25(15), 4731; https://doi.org/10.3390/s25154731 (registering DOI) - 31 Jul 2025
Abstract
The current paper presents a comprehensive intelligent system designed to optimize the performance of a barrier eddy current separator (BECS), comprising a conveyor belt, a vibration feeder, and a magnetic drum. This system was trained and validated on real-world industrial data gathered directly [...] Read more.
The current paper presents a comprehensive intelligent system designed to optimize the performance of a barrier eddy current separator (BECS), comprising a conveyor belt, a vibration feeder, and a magnetic drum. This system was trained and validated on real-world industrial data gathered directly from the working separator under 81 different operational scenarios. The intelligent models were used to recommend optimal settings for drum speed, belt speed, vibration intensity, and drum angle, thereby maximizing separation quality and minimizing energy consumption. the smart separation module utilizes YOLOv11n-seg and achieves a mean average precision (mAP) of 0.838 across 7163 industrial instances from aluminum, copper, and plastic materials. For shape classification (sharp vs. smooth), the model reached 91.8% accuracy across 1105 annotated samples. Furthermore, the thermal monitoring unit can detect iron contamination by analyzing temperature anomalies. Scenarios with iron showed a maximum temperature increase of over 20 °C compared to clean materials, with a detection response time of under 2.5 s. The architecture integrates a Digital Twin using Azure Digital Twins to virtually mirror the system, enabling real-time tracking, behavior simulation, and remote updates. A full connection with the PLC has been implemented, allowing the AI-driven system to adjust physical parameters autonomously. This combination of AI, IoT, and digital twin technologies delivers a reliable and scalable solution for enhanced separation quality, improved operational safety, and predictive maintenance in industrial recycling environments. Full article
(This article belongs to the Special Issue Sensors and IoT Technologies for the Smart Industry)
14 pages, 1980 KiB  
Review
Ultrasound in Adhesive Capsulitis: A Narrative Exploration from Static Imaging to Contrast-Enhanced, Dynamic and Sonoelastographic Insights
by Wei-Ting Wu, Ke-Vin Chang, Kamal Mezian, Vincenzo Ricci, Consuelo B. Gonzalez-Suarez and Levent Özçakar
Diagnostics 2025, 15(15), 1924; https://doi.org/10.3390/diagnostics15151924 - 31 Jul 2025
Viewed by 49
Abstract
Adhesive capsulitis is a painful and progressive condition marked by significant limitations in shoulder mobility, particularly affecting external rotation. Although magnetic resonance imaging is regarded as the reference standard for assessing intra-articular structures, its high cost and limited availability present challenges in routine [...] Read more.
Adhesive capsulitis is a painful and progressive condition marked by significant limitations in shoulder mobility, particularly affecting external rotation. Although magnetic resonance imaging is regarded as the reference standard for assessing intra-articular structures, its high cost and limited availability present challenges in routine clinical use. In contrast, musculoskeletal ultrasound has emerged as an accessible, real-time, and cost-effective imaging modality for both the diagnosis and treatment guidance of adhesive capsulitis. This narrative review compiles and illustrates current evidence regarding the role of ultrasound, encompassing static B-mode imaging, dynamic motion analysis, contrast-enhanced techniques, and sonoelastography. Key sonographic features—such as thickening of the coracohumeral ligament, fibrosis in the axillary recess, and abnormal tendon kinematics—have been consistently associated with adhesive capsulitis and demonstrate favorable diagnostic performance. Advanced methods like contrast-enhanced ultrasound and elastography provide additional functional insights (enabling evaluation of capsular stiffness and vascular changes) which may aid in disease staging and prediction of treatment response. Despite these advantages, the clinical utility of ultrasound remains subject to operator expertise and technical variability. Limited visualization of intra-articular structures and the absence of standardized scanning protocols continue to pose challenges. Nevertheless, ongoing advances in its technology and utility standardization hold promise for the broader application of ultrasound in clinical practice. With continued research and validation, ultrasound is positioned to play an increasingly central role in the comprehensive assessment and management of adhesive capsulitis. Full article
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17 pages, 3206 KiB  
Article
Inverse Punicines: Isomers of Punicine and Their Application in LiAlO2, Melilite and CaSiO3 Separation
by Maximilian H. Fischer, Ali Zgheib, Iliass El Hraoui, Alena Schnickmann, Thomas Schirmer, Gunnar Jeschke and Andreas Schmidt
Separations 2025, 12(8), 202; https://doi.org/10.3390/separations12080202 - 30 Jul 2025
Viewed by 86
Abstract
The transition to sustainable energy systems demands efficient recycling methods for critical raw materials like lithium. In this study, we present a new class of pH- and light-switchable flotation collectors based on isomeric derivatives of the natural product Punicine, termed inverse Punicines. [...] Read more.
The transition to sustainable energy systems demands efficient recycling methods for critical raw materials like lithium. In this study, we present a new class of pH- and light-switchable flotation collectors based on isomeric derivatives of the natural product Punicine, termed inverse Punicines. These amphoteric molecules were synthesized via a straightforward four-step route and structurally tuned for hydrophobization by alkylation. Their performance as collectors was evaluated in microflotation experiments of lithium aluminate (LiAlO2) and silicate matrix minerals such as melilite and calcium silicate. Characterization techniques including ultraviolet-visible (UV-Vis), nuclear magnetic resonance (NMR) and electron spin resonance (ESR) spectroscopy as well as contact angle, zeta potential (ζ potential) and microflotation experiments revealed strong pH- and structure-dependent interactions with mineral surfaces. Notably, N-alkylated inverse Punicine derivatives showed high flotation yields for LiAlO2 at pH of 11, with a derivative possessing a dodecyl group attached to the nitrogen as collector achieving up to 86% recovery (collector conc. 0.06 mmol/L). Preliminary separation tests showed Li upgrading from 5.27% to 6.95%. Radical formation and light-response behavior were confirmed by ESR and flotation tests under different illumination conditions. These results demonstrate the potential of inverse Punicines as tunable, sustainable flotation reagents for advanced lithium recycling from complex slag systems. Full article
(This article belongs to the Special Issue Application of Green Flotation Technology in Mineral Processing)
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19 pages, 4569 KiB  
Article
Tailored Magnetic Fe3O4-Based Core–Shell Nanoparticles Coated with TiO2 and SiO2 via Co-Precipitation: Structure–Property Correlation for Medical Imaging Applications
by Elena Emanuela Herbei, Daniela Laura Buruiana, Alina Crina Muresan, Viorica Ghisman, Nicoleta Lucica Bogatu, Vasile Basliu, Claudiu-Ionut Vasile and Lucian Barbu-Tudoran
Diagnostics 2025, 15(15), 1912; https://doi.org/10.3390/diagnostics15151912 - 30 Jul 2025
Viewed by 89
Abstract
Background/Objectives: Magnetic nanoparticles, particularly iron oxide-based materials, such as magnetite (Fe3O4), have gained significant attention as contrast agents in medical imaging This study aimsto syntheze and characterize Fe3O4-based core–shell nanostructures, including Fe3O4 [...] Read more.
Background/Objectives: Magnetic nanoparticles, particularly iron oxide-based materials, such as magnetite (Fe3O4), have gained significant attention as contrast agents in medical imaging This study aimsto syntheze and characterize Fe3O4-based core–shell nanostructures, including Fe3O4@TiO2 and Fe3O4@SiO2, and to evaluate their potential as tunable contrast agents for diagnostic imaging. Methods: Fe3O4, Fe3O4@TiO2, and Fe3O4@SiO2 nanoparticles were synthesized via co-precipitation at varying temperatures from iron salt precursors. Fourier transform infrared spectroscopy (FTIR) was used to confirm the presence of Fe–O bonds, while X-ray diffraction (XRD) was employed to determine the crystalline phases and estimate average crystallite sizes. Morphological analysis and particle size distribution were assessed by scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) and transmission electron microscopy (TEM). Magnetic properties were investigated using vibrating sample magnetometry (VSM). Results: FTIR spectra exhibited characteristic Fe–O vibrations at 543 cm−1 and 555 cm−1, indicating the formation of magnetite. XRD patterns confirmed a dominant cubic magnetite phase, with the presence of rutile TiO2 and stishovite SiO2 in the coated samples. The average crystallite sizes ranged from 24 to 95 nm. SEM and TEM analyses revealed particle sizes between 5 and 150 nm with well-defined core–shell morphologies. VSM measurements showed saturation magnetization (Ms) values ranging from 40 to 70 emu/g, depending on the synthesis temperature and shell composition. The highest Ms value was obtained for uncoated Fe3O4 synthesized at 94 °C. Conclusions: The synthesized Fe3O4-based core–shell nanomaterials exhibit desirable structural, morphological, and magnetic properties for use as contrast agents. Their tunable magnetic response and nanoscale dimensions make them promising candidates for advanced diagnostic imaging applications. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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20 pages, 6964 KiB  
Article
Mineralogical Analysis of Factors Affecting the Grade of High-Gradient Magnetic Separation Concentrates and Experimental Study on TiO2 Enrichment Using ARC
by Yifei Liu, Zhenqiang Liu, Yuhua Wang, Yuxin Zhang and Dongfang Lu
Minerals 2025, 15(8), 799; https://doi.org/10.3390/min15080799 - 30 Jul 2025
Viewed by 148
Abstract
High-gradient magnetic separation is a key step in the pre-concentration of ilmenite before flotation, particularly in the gravity separation process. However, as the amount of weakly magnetic gangue minerals increases, the grade of the coarse concentrate from high-gradient magnetic separation decreases. This paper [...] Read more.
High-gradient magnetic separation is a key step in the pre-concentration of ilmenite before flotation, particularly in the gravity separation process. However, as the amount of weakly magnetic gangue minerals increases, the grade of the coarse concentrate from high-gradient magnetic separation decreases. This paper investigates the mineralogical factors affecting the enrichment efficiency of high-gradient magnetic separation. Additionally, a newly developed stirred fluidized bed device, an agitated reflux classifier (ARC), was successfully applied to remove weakly magnetic gangue minerals that are difficult to separate by high-gradient magnetic separation (HGMS). For low-grade ilmenite with a feed grade of 3.97%, a combined process of magnetic separation and gravity separation was employed, achieving a concentrate with a grade of 16.50% and a recovery rate of 54.11%. This concentrate meets the requirements for flotation feed. This study provides a new approach for the beneficiation of low-grade ilmenite. Full article
(This article belongs to the Section Mineral Processing and Extractive Metallurgy)
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11 pages, 1176 KiB  
Article
Nonreciprocal Transport Driven by Noncoplanar Magnetic Ordering with Meron–Antimeron Spin Textures
by Satoru Hayami
Solids 2025, 6(3), 40; https://doi.org/10.3390/solids6030040 - 29 Jul 2025
Viewed by 177
Abstract
Noncoplanar spin textures give rise not only to unusual magnetic structures but also to emergent electromagnetic responses stemming from scalar spin chirality, such as the topological Hall effect. In this study, we theoretically investigate nonreciprocal transport phenomena induced by noncoplanar magnetic orderings through [...] Read more.
Noncoplanar spin textures give rise not only to unusual magnetic structures but also to emergent electromagnetic responses stemming from scalar spin chirality, such as the topological Hall effect. In this study, we theoretically investigate nonreciprocal transport phenomena induced by noncoplanar magnetic orderings through microscopic model analyses. By focusing on meron–antimeron spin textures that exhibit local scalar spin chirality while maintaining vanishing global chirality, we demonstrate that the electronic band structure becomes asymmetrically modulated, which leads to the emergence of nonreciprocal transport. The present mechanism arises purely from the noncoplanar magnetic texture itself and requires neither net magnetization nor relativistic spin–orbit coupling. We further discuss the potential relevance of our findings to the compound Gd2PdSi3, which has been suggested to host a meron–antimeron crystal phase at low temperatures. Full article
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22 pages, 2875 KiB  
Article
Optimization of Test Mass Motion State for Enhancing Stiffness Identification Performance in Space Gravitational Wave Detection
by Ningbiao Tang, Ziruo Fang, Zhongguang Yang, Zhiming Cai, Haiying Hu and Huawang Li
Aerospace 2025, 12(8), 673; https://doi.org/10.3390/aerospace12080673 - 28 Jul 2025
Viewed by 121
Abstract
In space gravitational wave detection, various physical effects in the spacecraft, such as self-gravity, electricity, and magnetism, will introduce undesirable parasitic stiffness. The coupling noise between stiffness and the motion states of the test mass critically affects the performance of scientific detection, making [...] Read more.
In space gravitational wave detection, various physical effects in the spacecraft, such as self-gravity, electricity, and magnetism, will introduce undesirable parasitic stiffness. The coupling noise between stiffness and the motion states of the test mass critically affects the performance of scientific detection, making accurate stiffness identification crucial. In response to the question, this paper proposes a method to optimize the test mass motion state for enhancing stiffness identification performance. First, the dynamics of the test mass are studied and a recursive least squares algorithm is applied for the implementation of on-orbit stiffness identification. Then, the motion state of the test mass is parametrically characterized by multi-frequency sinusoidal signals as the variable to be optimized, with the optimization objectives and constraints of stiffness identification defined based on convergence time, convergence accuracy, and engineering requirements. To tackle the dual-objective, computationally expensive nature of the problem, a multigranularity surrogate-assisted evolutionary algorithm with individual progressive constraints (MGSAEA-IPC) is proposed. A fuzzy radial basis function neural network PID (FRBF-PID) controller is also designed to address complex control needs under varying motion states. Numerical simulations demonstrate that the convergence time after optimization is less than 2 min, and the convergence accuracy is less than 1.5 × 10−10 s−2. This study can provide ideas and design references for subsequent related identification and control missions. Full article
(This article belongs to the Section Astronautics & Space Science)
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16 pages, 1160 KiB  
Article
PMSM Control Paradigm Shift: Hybrid Dual Fractional-Order Sliding Mode Control with Evolutionary Parameter Learning
by Peng Gao, Liandi Fang and Huihui Pan
Fractal Fract. 2025, 9(8), 491; https://doi.org/10.3390/fractalfract9080491 - 25 Jul 2025
Viewed by 189
Abstract
This study introduces a paradigm shift in permanent magnet synchronous motor (PMSM) control through the development of hybrid dual fractional-order sliding mode control (HDFOSMC) architecture integrated with evolutionary parameter learning (EPL). Conventional PMSM control frameworks face critical limitations in ultra-precision applications due to [...] Read more.
This study introduces a paradigm shift in permanent magnet synchronous motor (PMSM) control through the development of hybrid dual fractional-order sliding mode control (HDFOSMC) architecture integrated with evolutionary parameter learning (EPL). Conventional PMSM control frameworks face critical limitations in ultra-precision applications due to their inability to reconcile dynamic agility with steady-state precision under time-varying parameters and compound disturbances. The proposed HDFOSMC framework addresses these challenges via two synergistic innovations: (1) a dual fractional-order sliding manifold that fuses the rapid transient response of non-integer-order differentiation with the small steady-state error capability of dual-integral compensation, and (2) an EPL mechanism enabling real-time adaptation to thermal drift, load mutations, and unmodeled nonlinearities. Validation can be obtained through the comparison of the results on PMSM testbenches, which demonstrate superior performance over traditional fractional-order sliding mode control (FOSMC). By integrating fractional-order theory, sliding mode control theory, and parameter self-tuning theory, this study proposes a novel control framework for PMSM. The developed system achieves high-precision performance under extreme operational uncertainties through this innovative theoretical synthesis and comparative results. Full article
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12 pages, 620 KiB  
Review
Manganese-Based Contrast Agents as Alternatives to Gadolinium: A Comprehensive Review
by Linda Poggiarelli, Caterina Bernetti, Luca Pugliese, Federico Greco, Bruno Beomonte Zobel and Carlo A. Mallio
Clin. Pract. 2025, 15(8), 137; https://doi.org/10.3390/clinpract15080137 - 25 Jul 2025
Viewed by 239
Abstract
Background/Objectives: Magnetic resonance imaging (MRI) is a powerful, non-invasive diagnostic tool capable of capturing detailed anatomical and physiological information. MRI contrast agents enhance image contrast but, especially linear gadolinium-based compounds, have been associated with safety concerns. This has prompted interest in alternative contrast [...] Read more.
Background/Objectives: Magnetic resonance imaging (MRI) is a powerful, non-invasive diagnostic tool capable of capturing detailed anatomical and physiological information. MRI contrast agents enhance image contrast but, especially linear gadolinium-based compounds, have been associated with safety concerns. This has prompted interest in alternative contrast agents. Manganese-based contrast agents offer a promising substitute, owing to manganese’s favorable magnetic properties, natural biological role, and strong T1 relaxivity. This review aims to critically assess the structure, mechanisms, applications, and challenges of manganese-based contrast agents in MRI. Methods: This review synthesizes findings from preclinical and clinical studies involving various types of manganese-based contrast agents, including small-molecule chelates, nanoparticles, theranostic platforms, responsive agents, and controlled-release systems. Special attention is given to pharmacokinetics, biodistribution, and safety evaluations. Results: Mn-based agents demonstrate promising imaging capabilities, with some achieving relaxivity values comparable to gadolinium compounds. Targeted uptake mechanisms, such as hepatocyte-specific transport via organic anion-transporting polypeptides, allow for enhanced tissue contrast. However, concerns remain regarding the in vivo release of free Mn2+ ions, which could lead to toxicity. Preliminary toxicity assessments report low cytotoxicity, but further comprehensive long-term safety studies should be carried out. Conclusions: Manganese-based contrast agents present a potential alternative to gadolinium-based MRI agents pending further validation. Despite promising imaging performance and biocompatibility, further investigation into stability and safety is essential. Additional research is needed to facilitate the clinical translation of these agents. Full article
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