Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (5,758)

Search Parameters:
Keywords = intelligent solutions

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
38 pages, 1194 KiB  
Review
Transforming Data Annotation with AI Agents: A Review of Architectures, Reasoning, Applications, and Impact
by Md Monjurul Karim, Sangeen Khan, Dong Hoang Van, Xinyue Liu, Chunhui Wang and Qiang Qu
Future Internet 2025, 17(8), 353; https://doi.org/10.3390/fi17080353 (registering DOI) - 2 Aug 2025
Abstract
Data annotation serves as a critical foundation for artificial intelligence (AI) and machine learning (ML). Recently, AI agents powered by large language models (LLMs) have emerged as effective solutions to longstanding challenges in data annotation, such as scalability, consistency, cost, and limitations in [...] Read more.
Data annotation serves as a critical foundation for artificial intelligence (AI) and machine learning (ML). Recently, AI agents powered by large language models (LLMs) have emerged as effective solutions to longstanding challenges in data annotation, such as scalability, consistency, cost, and limitations in domain expertise. These agents facilitate intelligent automation and adaptive decision-making, thereby enhancing the efficiency and reliability of annotation workflows across various fields. Despite the growing interest in this area, a systematic understanding of the role and capabilities of AI agents in annotation is still underexplored. This paper seeks to fill that gap by providing a comprehensive review of how LLM-driven agents support advanced reasoning strategies, adaptive learning, and collaborative annotation efforts. We analyze agent architectures, integration patterns within workflows, and evaluation methods, along with real-world applications in sectors such as healthcare, finance, technology, and media. Furthermore, we evaluate current tools and platforms that support agent-based annotation, addressing key challenges such as quality assurance, bias mitigation, transparency, and scalability. Lastly, we outline future research directions, highlighting the importance of federated learning, cross-modal reasoning, and responsible system design to advance the development of next-generation annotation ecosystems. Full article
Show Figures

Figure 1

17 pages, 1651 KiB  
Article
A Comprehensive User Acceptance Evaluation Framework of Intelligent Driving Based on Subjective and Objective Integration—From the Perspective of Value Engineering
by Wang Zhang, Fuquan Zhao, Zongwei Liu, Haokun Song and Guangyu Zhu
Systems 2025, 13(8), 653; https://doi.org/10.3390/systems13080653 (registering DOI) - 2 Aug 2025
Abstract
Intelligent driving technology is expected to reshape urban transportation, but its promotion is hindered by user acceptance challenges and diverse technical routes. This study proposes a comprehensive user acceptance evaluation framework for intelligent driving from the perspective of value engineering (VE). The novelty [...] Read more.
Intelligent driving technology is expected to reshape urban transportation, but its promotion is hindered by user acceptance challenges and diverse technical routes. This study proposes a comprehensive user acceptance evaluation framework for intelligent driving from the perspective of value engineering (VE). The novelty of this framework lies in three aspects: (1) It unifies behavioral theory and utility theory under the value engineering framework, and it extracts key indicators such as safety, travel efficiency, trust, comfort, and cost, thus addressing the issue of the lack of integration between subjective and objective factors in previous studies. (2) It establishes a systematic mapping mechanism from technical solutions to evaluation indicators, filling the gap of insufficient targeting at different technical routes in the existing literature. (3) It quantifies acceptance differences via VE’s core formula of V = F/C, overcoming the ambiguity of non-technical evaluation in prior research. A case study comparing single-vehicle intelligence vs. collaborative intelligence and different sensor combinations (vision-only, map fusion, and lidar fusion) shows that collaborative intelligence and vision-based solutions offer higher comprehensive acceptance due to balanced functionality and cost. This framework guides enterprises in technical strategy planning and assists governments in formulating industrial policies by quantifying acceptance differences across technical routes. Full article
(This article belongs to the Special Issue Modeling, Planning and Management of Sustainable Transport Systems)
22 pages, 3301 KiB  
Article
Parameter Identification of Distribution Zone Transformers Under Three-Phase Asymmetric Conditions
by Panrun Jin, Wenqin Song and Yankui Zhang
Eng 2025, 6(8), 181; https://doi.org/10.3390/eng6080181 (registering DOI) - 2 Aug 2025
Abstract
As a core device in low-voltage distribution networks, the distribution zone transformer (DZT) is influenced by short circuits, overloads, and unbalanced loads, which cause thermal aging, mechanical stress, and eventually deformation of the winding, resulting in parameter deviations from nameplate values and impairing [...] Read more.
As a core device in low-voltage distribution networks, the distribution zone transformer (DZT) is influenced by short circuits, overloads, and unbalanced loads, which cause thermal aging, mechanical stress, and eventually deformation of the winding, resulting in parameter deviations from nameplate values and impairing system operation. However, existing identification methods typically require synchronized high- and low-voltage data and are limited to symmetric three-phase conditions, which limits their application in practical distribution systems. To address these challenges, this paper proposes a parameter identification method for DZTs under three-phase unbalanced conditions. Firstly, based on the transformer’s T-equivalent circuit considering the load, the power flow equations are derived without involving the synchronization issue of high-voltage and low-voltage side data, and the sum of the impedances on both sides is treated as an independent parameter. Then, a novel power flow equation under three-phase unbalanced conditions is established, and an adaptive recursive least squares (ARLS) solution method is constructed using the measurement data sequence provided by the smart meter of the intelligent transformer terminal unit (TTU) to achieve online identification of the transformer winding parameters. The effectiveness and robustness of the method are verified through practical case studies. Full article
Show Figures

Figure 1

23 pages, 3120 KiB  
Article
Bee Swarm Metropolis–Hastings Sampling for Bayesian Inference in the Ginzburg–Landau Equation
by Shucan Xia and Lipu Zhang
Algorithms 2025, 18(8), 476; https://doi.org/10.3390/a18080476 (registering DOI) - 2 Aug 2025
Abstract
To improve the sampling efficiency of Markov Chain Monte Carlo in complex parameter spaces, this paper proposes an adaptive sampling method that integrates a swarm intelligence mechanism called the BeeSwarm-MH algorithm. The method combines global exploration by scout bees with local exploitation by [...] Read more.
To improve the sampling efficiency of Markov Chain Monte Carlo in complex parameter spaces, this paper proposes an adaptive sampling method that integrates a swarm intelligence mechanism called the BeeSwarm-MH algorithm. The method combines global exploration by scout bees with local exploitation by worker bees. It employs multi-stage perturbation intensities and adaptive step-size tuning to enable efficient posterior sampling. Focusing on Bayesian inference for parameter estimation in the soliton solutions of the two-dimensional complex Ginzburg–Landau equation, we design a dedicated inference framework to systematically compare the performance of BeeSwarm-MH with the classical Metropolis–Hastings algorithm. Experimental results demonstrate that BeeSwarm-MH achieves comparable estimation accuracy while significantly reducing the required number of iterations and total computation time for convergence. Moreover, it exhibits superior global search capabilities and adaptive features, offering a practical approach for efficient Bayesian inference in complex physical models. Full article
18 pages, 6891 KiB  
Article
Physics-Based Data Augmentation Enables Accurate Machine Learning Prediction of Melt Pool Geometry
by Siqi Liu, Ruina Li, Jiayi Zhou, Chaoyuan Dai, Jingui Yu and Qiaoxin Zhang
Appl. Sci. 2025, 15(15), 8587; https://doi.org/10.3390/app15158587 (registering DOI) - 2 Aug 2025
Abstract
Accurate melt pool geometry prediction is essential for ensuring quality and reliability in Laser Powder Bed Fusion (L-PBF). However, small experimental datasets and limited physical interpretability often restrict the effectiveness of traditional machine learning (ML) models. This study proposes a hybrid framework that [...] Read more.
Accurate melt pool geometry prediction is essential for ensuring quality and reliability in Laser Powder Bed Fusion (L-PBF). However, small experimental datasets and limited physical interpretability often restrict the effectiveness of traditional machine learning (ML) models. This study proposes a hybrid framework that integrates an explicit thermal model with ML algorithms to improve prediction under sparse data conditions. The explicit model—calibrated for variable penetration depth and absorptivity—generates synthetic melt pool data, augmenting 36 experimental samples across conduction, transition, and keyhole regimes for 316 L stainless steel. Three ML methods—Multilayer Perceptron (MLP), Random Forest, and XGBoost—are trained using fivefold cross-validation. The hybrid approach significantly improves prediction accuracy, especially in unstable transition regions (D/W ≈ 0.5–1.2), where morphological fluctuations hinder experimental sampling. The best-performing model (MLP) achieves R2 > 0.98, with notable reductions in MAE and RMSE. The results highlight the benefit of incorporating physically consistent, nonlinearly distributed synthetic data to enhance generalization and robustness. This physics-augmented learning strategy not only demonstrates scientific novelty by integrating mechanistic modeling into data-driven learning, but also provides a scalable solution for intelligent process optimization, in situ monitoring, and digital twin development in metal additive manufacturing. Full article
Show Figures

Figure 1

19 pages, 2359 KiB  
Article
Research on Concrete Crack Damage Assessment Method Based on Pseudo-Label Semi-Supervised Learning
by Ming Xie, Zhangdong Wang and Li’e Yin
Buildings 2025, 15(15), 2726; https://doi.org/10.3390/buildings15152726 (registering DOI) - 1 Aug 2025
Abstract
To address the inefficiency of traditional concrete crack detection methods and the heavy reliance of supervised learning on extensive labeled data, in this study, an intelligent assessment method of concrete damage based on pseudo-label semi-supervised learning and fractal geometry theory is proposed to [...] Read more.
To address the inefficiency of traditional concrete crack detection methods and the heavy reliance of supervised learning on extensive labeled data, in this study, an intelligent assessment method of concrete damage based on pseudo-label semi-supervised learning and fractal geometry theory is proposed to solve two core tasks: one is binary classification of pixel-level cracks, and the other is multi-category assessment of damage state based on crack morphology. Using three-channel RGB images as input, a dual-path collaborative training framework based on U-Net encoder–decoder architecture is constructed, and a binary segmentation mask of the same size is output to achieve the accurate segmentation of cracks at the pixel level. By constructing a dual-path collaborative training framework and employing a dynamic pseudo-label refinement mechanism, the model achieves an F1-score of 0.883 using only 50% labeled data—a mere 1.3% decrease compared to the fully supervised benchmark DeepCrack (F1 = 0.896)—while reducing manual annotation costs by over 60%. Furthermore, a quantitative correlation model between crack fractal characteristics and structural damage severity is established by combining a U-Net segmentation network with the differential box-counting algorithm. The experimental results demonstrate that under a cyclic loading of 147.6–221.4 kN, the fractal dimension monotonically increases from 1.073 (moderate damage) to 1.189 (failure), with 100% accuracy in damage state identification, closely aligning with the degradation trend of macroscopic mechanical properties. In complex crack scenarios, the model attains a recall rate (Re = 0.882), surpassing U-Net by 13.9%, with significantly enhanced edge reconstruction precision. Compared with the mainstream models, this method effectively alleviates the problem of data annotation dependence through a semi-supervised strategy while maintaining high accuracy. It provides an efficient structural health monitoring solution for engineering practice, which is of great value to promote the application of intelligent detection technology in infrastructure operation and maintenance. Full article
Show Figures

Figure 1

28 pages, 2465 KiB  
Article
Latency-Aware and Energy-Efficient Task Offloading in IoT and Cloud Systems with DQN Learning
by Amina Benaboura, Rachid Bechar, Walid Kadri, Tu Dac Ho, Zhenni Pan and Shaaban Sahmoud
Electronics 2025, 14(15), 3090; https://doi.org/10.3390/electronics14153090 (registering DOI) - 1 Aug 2025
Abstract
The exponential proliferation of the Internet of Things (IoT) and optical IoT (O-IoT) has introduced substantial challenges concerning computational capacity and energy efficiency. IoT devices generate vast volumes of aggregated data and require intensive processing, often resulting in elevated latency and excessive energy [...] Read more.
The exponential proliferation of the Internet of Things (IoT) and optical IoT (O-IoT) has introduced substantial challenges concerning computational capacity and energy efficiency. IoT devices generate vast volumes of aggregated data and require intensive processing, often resulting in elevated latency and excessive energy consumption. Task offloading has emerged as a viable solution; however, many existing strategies fail to adequately optimize both latency and energy usage. This paper proposes a novel task-offloading approach based on deep Q-network (DQN) learning, designed to intelligently and dynamically balance these critical metrics. The proposed framework continuously refines real-time task offloading decisions by leveraging the adaptive learning capabilities of DQN, thereby substantially reducing latency and energy consumption. To further enhance system performance, the framework incorporates optical networks into the IoT–fog–cloud architecture, capitalizing on their high-bandwidth and low-latency characteristics. This integration facilitates more efficient distribution and processing of tasks, particularly in data-intensive IoT applications. Additionally, we present a comparative analysis between the proposed DQN algorithm and the optimal strategy. Through extensive simulations, we demonstrate the superior effectiveness of the proposed DQN framework across various IoT and O-IoT scenarios compared to the BAT and DJA approaches, achieving improvements in energy consumption and latency of 35%, 50%, 30%, and 40%, respectively. These findings underscore the significance of selecting an appropriate offloading strategy tailored to the specific requirements of IoT and O-IoT applications, particularly with regard to environmental stability and performance demands. Full article
Show Figures

Figure 1

20 pages, 865 KiB  
Review
Barriers and Facilitators to Artificial Intelligence Implementation in Diabetes Management from Healthcare Workers’ Perspective: A Scoping Review
by Giovanni Cangelosi, Andrea Conti, Gabriele Caggianelli, Massimiliano Panella, Fabio Petrelli, Stefano Mancin, Matteo Ratti and Alice Masini
Medicina 2025, 61(8), 1403; https://doi.org/10.3390/medicina61081403 (registering DOI) - 1 Aug 2025
Abstract
Background and Objectives: Diabetes is a global public health challenge, with increasing prevalence worldwide. The implementation of artificial intelligence (AI) in the management of this condition offers potential benefits in improving healthcare outcomes. This study primarily investigates the barriers and facilitators perceived by [...] Read more.
Background and Objectives: Diabetes is a global public health challenge, with increasing prevalence worldwide. The implementation of artificial intelligence (AI) in the management of this condition offers potential benefits in improving healthcare outcomes. This study primarily investigates the barriers and facilitators perceived by healthcare professionals in the adoption of AI. Secondarily, by analyzing both quantitative and qualitative data collected, it aims to support the potential development of AI-based programs for diabetes management, with particular focus on a possible bottom-up approach. Materials and Methods: A scoping review was conducted following PRISMA-ScR guidelines for reporting and registered in the Open Science Framework (OSF) database. The study selection process was conducted in two phases—title/abstract screening and full-text review—independently by three researchers, with a fourth resolving conflicts. Data were extracted and assessed using Joanna Briggs Institute (JBI) tools. The included studies were synthesized narratively, combining both quantitative and qualitative analyses to ensure methodological rigor and contextual depth. Results: The adoption of AI tools in diabetes management is influenced by several barriers, including perceived unsatisfactory clinical performance, high costs, issues related to data security and decision-making transparency, as well as limited training among healthcare workers. Key facilitators include improved clinical efficiency, ease of use, time-saving, and organizational support, which contribute to broader acceptance of the technology. Conclusions: The active and continuous involvement of healthcare workers represents a valuable opportunity to develop more effective, reliable, and well-integrated AI solutions in clinical practice. Our findings emphasize the importance of a bottom-up approach and highlight how adequate training and organizational support can help overcome existing barriers, promoting sustainable and equitable innovation aligned with public health priorities. Full article
(This article belongs to the Special Issue Advances in Public Health and Healthcare Management for Chronic Care)
14 pages, 483 KiB  
Review
Artificial Intelligence and Its Impact on the Management of Lumbar Degenerative Pathology: A Narrative Review
by Alessandro Trento, Salvatore Rapisarda, Nicola Bresolin, Andrea Valenti and Enrico Giordan
Medicina 2025, 61(8), 1400; https://doi.org/10.3390/medicina61081400 (registering DOI) - 1 Aug 2025
Abstract
In this narrative review, we explore the role of artificial intelligence (AI) in managing lumbar degenerative conditions, a topic that has recently garnered significant interest. The use of AI-based solutions in spine surgery is particularly appealing due to its potential applications in preoperative [...] Read more.
In this narrative review, we explore the role of artificial intelligence (AI) in managing lumbar degenerative conditions, a topic that has recently garnered significant interest. The use of AI-based solutions in spine surgery is particularly appealing due to its potential applications in preoperative planning and outcome prediction. This study aims to clarify the impact of artificial intelligence models on the diagnosis and prognosis of common types of degenerative conditions: lumbar disc herniation, spinal stenosis, and eventually spinal fusion. Additionally, the study seeks to identify predictive factors for lumbar fusion surgery based on a review of the literature from the past 10 years. From the literature search, 96 articles were examined. The literature on this topic appears to be consistent, describing various models that show promising results, particularly in predicting outcomes. However, most studies adopt a retrospective approach and often lack detailed information about imaging features, intraoperative findings, and postoperative functional metrics. Additionally, the predictive performance of these models varies significantly, and few studies include external validation. The application of artificial intelligence in treating degenerative spine conditions, while valid and promising, is still in a developmental phase. However, over the last decade, there has been an exponential growth in studies related to this subject, which is beginning to pave the way for its systematic use in clinical practice. Full article
Show Figures

Figure 1

31 pages, 3315 KiB  
Article
Searching for the Best Artificial Neural Network Architecture to Estimate Column and Beam Element Dimensions
by Ayla Ocak, Gebrail Bekdaş, Sinan Melih Nigdeli, Umit Işıkdağ and Zong Woo Geem
Information 2025, 16(8), 660; https://doi.org/10.3390/info16080660 (registering DOI) - 1 Aug 2025
Abstract
The cross-sectional dimensions of structural elements in a structure are design elements that need to be carefully designed and are related to the stiffness of the structure. Various optimization processes are applied to determine the optimum cross-sectional dimensions of beams or columns in [...] Read more.
The cross-sectional dimensions of structural elements in a structure are design elements that need to be carefully designed and are related to the stiffness of the structure. Various optimization processes are applied to determine the optimum cross-sectional dimensions of beams or columns in structures. By repeating the optimization processes for multiple load scenarios, it is possible to create a data set that shows the optimum design section properties. However, this step means repeating the same processes to produce the optimum cross-sectional dimensions. Artificial intelligence technology offers a short-cut solution to this by providing the opportunity to train itself with previously generated optimum cross-sectional dimensions and infer new cross-sectional dimensions. By processing the data, the artificial neural network can generate models that predict the cross-section for a new structural element. In this study, an optimization process is applied to a simple tubular column and an I-section beam, and the results are compiled to create a data set that presents the optimum section dimensions as a class. The harmony search (HS) algorithm, which is a metaheuristic method, was used in optimization. An artificial neural network (ANN) was created to predict the cross-sectional dimensions of the sample structural elements. The neural architecture search (NAS) method, which incorporates many metaheuristic algorithms designed to search for the best artificial neural network architecture, was applied. In this method, the best values of various parameters of the neural network, such as activation function, number of layers, and neurons, are searched for in the model with a tool called HyperNetExplorer. Model metrics were calculated to evaluate the prediction success of the developed model. An effective neural network architecture for column and beam elements is obtained. Full article
(This article belongs to the Special Issue Optimization Algorithms and Their Applications)
Show Figures

Figure 1

25 pages, 2515 KiB  
Article
Solar Agro Savior: Smart Agricultural Monitoring Using Drones and Deep Learning Techniques
by Manu Mundappat Ramachandran, Bisni Fahad Mon, Mohammad Hayajneh, Najah Abu Ali and Elarbi Badidi
Agriculture 2025, 15(15), 1656; https://doi.org/10.3390/agriculture15151656 - 1 Aug 2025
Abstract
The Solar Agro Savior (SAS) is an innovative solution that is assisted by drones for the sustainable utilization of water and plant disease observation in the agriculture sector. This system integrates an alerting mechanism for humidity, moisture, and temperature variations, which affect the [...] Read more.
The Solar Agro Savior (SAS) is an innovative solution that is assisted by drones for the sustainable utilization of water and plant disease observation in the agriculture sector. This system integrates an alerting mechanism for humidity, moisture, and temperature variations, which affect the plants’ health and optimization in water utilization, which enhances plant yield productivity. A significant feature of the system is the efficient monitoring system in a larger region through drones’ high-resolution cameras, which enables real-time, efficient response and alerting for environmental fluctuations to the authorities. The machine learning algorithm, particularly recurrent neural networks, which is a pioneer with agriculture and pest control, is incorporated for intelligent monitoring systems. The proposed system incorporates a specialized form of a recurrent neural network, Long Short-Term Memory (LSTM), which effectively addresses the vanishing gradient problem. It also utilizes an attention-based mechanism that enables the model to assign meaningful weights to the most important parts of the data sequence. This algorithm not only enhances water utilization efficiency but also boosts plant yield and strengthens pest control mechanisms. This system also provides sustainability through the re-utilization of water and the elimination of electric energy through solar panel systems for powering the inbuilt irrigation system. A comparative analysis of variant algorithms in the agriculture sector with a machine learning approach was also illustrated, and the proposed system yielded 99% yield accuracy, a 97.8% precision value, 98.4% recall, and a 98.4% F1 score value. By encompassing solar irrigation and artificial intelligence-driven analysis, the proposed algorithm, Solar Argo Savior, established a sustainable framework in the latest agricultural sectors and promoted sustainability to protect our environment and community. Full article
(This article belongs to the Section Agricultural Technology)
Show Figures

Figure 1

29 pages, 959 KiB  
Review
Machine Learning-Driven Insights in Cancer Metabolomics: From Subtyping to Biomarker Discovery and Prognostic Modeling
by Amr Elguoshy, Hend Zedan and Suguru Saito
Metabolites 2025, 15(8), 514; https://doi.org/10.3390/metabo15080514 (registering DOI) - 1 Aug 2025
Abstract
Cancer metabolic reprogramming plays a critical role in tumor progression and therapeutic resistance, underscoring the need for advanced analytical strategies. Metabolomics, leveraging mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, offers a comprehensive and functional readout of tumor biochemistry. By enabling both targeted [...] Read more.
Cancer metabolic reprogramming plays a critical role in tumor progression and therapeutic resistance, underscoring the need for advanced analytical strategies. Metabolomics, leveraging mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, offers a comprehensive and functional readout of tumor biochemistry. By enabling both targeted metabolite quantification and untargeted profiling, metabolomics captures the dynamic metabolic alterations associated with cancer. The integration of metabolomics with machine learning (ML) approaches further enhances the interpretation of these complex, high-dimensional datasets, providing powerful insights into cancer biology from biomarker discovery to therapeutic targeting. This review systematically examines the transformative role of ML in cancer metabolomics. We discuss how various ML methodologies—including supervised algorithms (e.g., Support Vector Machine, Random Forest), unsupervised techniques (e.g., Principal Component Analysis, t-SNE), and deep learning frameworks—are advancing cancer research. Specifically, we highlight three major applications of ML–metabolomics integration: (1) cancer subtyping, exemplified by the use of Similarity Network Fusion (SNF) and LASSO regression to classify triple-negative breast cancer into subtypes with distinct survival outcomes; (2) biomarker discovery, where Random Forest and Partial Least Squares Discriminant Analysis (PLS-DA) models have achieved >90% accuracy in detecting breast and colorectal cancers through biofluid metabolomics; and (3) prognostic modeling, demonstrated by the identification of race-specific metabolic signatures in breast cancer and the prediction of clinical outcomes in lung and ovarian cancers. Beyond these areas, we explore applications across prostate, thyroid, and pancreatic cancers, where ML-driven metabolomics is contributing to earlier detection, improved risk stratification, and personalized treatment planning. We also address critical challenges, including issues of data quality (e.g., batch effects, missing values), model interpretability, and barriers to clinical translation. Emerging solutions, such as explainable artificial intelligence (XAI) approaches and standardized multi-omics integration pipelines, are discussed as pathways to overcome these hurdles. By synthesizing recent advances, this review illustrates how ML-enhanced metabolomics bridges the gap between fundamental cancer metabolism research and clinical application, offering new avenues for precision oncology through improved diagnosis, prognosis, and tailored therapeutic strategies. Full article
(This article belongs to the Special Issue Nutritional Metabolomics in Cancer)
Show Figures

Figure 1

12 pages, 1346 KiB  
Article
A Language Vision Model Approach for Automated Tumor Contouring in Radiation Oncology
by Yi Luo, Hamed Hooshangnejad, Xue Feng, Gaofeng Huang, Xiaojian Chen, Rui Zhang, Quan Chen, Wil Ngwa and Kai Ding
Bioengineering 2025, 12(8), 835; https://doi.org/10.3390/bioengineering12080835 (registering DOI) - 31 Jul 2025
Abstract
Background: Lung cancer ranks as the leading cause of cancer-related mortality worldwide. The complexity of tumor delineation, crucial for radiation therapy, requires expertise often unavailable in resource-limited settings. Artificial Intelligence (AI), particularly with advancements in deep learning (DL) and natural language processing (NLP), [...] Read more.
Background: Lung cancer ranks as the leading cause of cancer-related mortality worldwide. The complexity of tumor delineation, crucial for radiation therapy, requires expertise often unavailable in resource-limited settings. Artificial Intelligence (AI), particularly with advancements in deep learning (DL) and natural language processing (NLP), offers potential solutions yet is challenged by high false positive rates. Purpose: The Oncology Contouring Copilot (OCC) system is developed to leverage oncologist expertise for precise tumor contouring using textual descriptions, aiming to increase the efficiency of oncological workflows by combining the strengths of AI with human oversight. Methods: Our OCC system initially identifies nodule candidates from CT scans. Employing Language Vision Models (LVMs) like GPT-4V, OCC then effectively reduces false positives with clinical descriptive texts, merging textual and visual data to automate tumor delineation, designed to elevate the quality of oncology care by incorporating knowledge from experienced domain experts. Results: The deployment of the OCC system resulted in a 35.0% reduction in the false discovery rate, a 72.4% decrease in false positives per scan, and an F1-score of 0.652 across our dataset for unbiased evaluation. Conclusions: OCC represents a significant advance in oncology care, particularly through the use of the latest LVMs, improving contouring results by (1) streamlining oncology treatment workflows by optimizing tumor delineation and reducing manual processes; (2) offering a scalable and intuitive framework to reduce false positives in radiotherapy planning using LVMs; (3) introducing novel medical language vision prompt techniques to minimize LVM hallucinations with ablation study; and (4) conducting a comparative analysis of LVMs, highlighting their potential in addressing medical language vision challenges. Full article
(This article belongs to the Special Issue Novel Imaging Techniques in Radiotherapy)
Show Figures

Figure 1

42 pages, 4490 KiB  
Review
Continuous Monitoring with AI-Enhanced BioMEMS Sensors: A Focus on Sustainable Energy Harvesting and Predictive Analytics
by Mingchen Cai, Hao Sun, Tianyue Yang, Hongxin Hu, Xubing Li and Yuan Jia
Micromachines 2025, 16(8), 902; https://doi.org/10.3390/mi16080902 (registering DOI) - 31 Jul 2025
Abstract
Continuous monitoring of environmental and physiological parameters is essential for early diagnostics, real-time decision making, and intelligent system adaptation. Recent advancements in bio-microelectromechanical systems (BioMEMS) sensors have significantly enhanced our ability to track key metrics in real time. However, continuous monitoring demands sustainable [...] Read more.
Continuous monitoring of environmental and physiological parameters is essential for early diagnostics, real-time decision making, and intelligent system adaptation. Recent advancements in bio-microelectromechanical systems (BioMEMS) sensors have significantly enhanced our ability to track key metrics in real time. However, continuous monitoring demands sustainable energy supply solutions, especially for on-site energy replenishment in areas with limited resources. Artificial intelligence (AI), particularly large language models, offers new avenues for interpreting the vast amounts of data generated by these sensors. Despite this potential, fully integrated systems that combine self-powered BioMEMS sensing with AI-based analytics remain in the early stages of development. This review first examines the evolution of BioMEMS sensors, focusing on advances in sensing materials, micro/nano-scale architectures, and fabrication techniques that enable high sensitivity, flexibility, and biocompatibility for continuous monitoring applications. We then examine recent advances in energy harvesting technologies, such as piezoelectric nanogenerators, triboelectric nanogenerators and moisture electricity generators, which enable self-powered BioMEMS sensors to operate continuously and reducereliance on traditional batteries. Finally, we discuss the role of AI in BioMEMS sensing, particularly in predictive analytics, to analyze continuous monitoring data, identify patterns, trends, and anomalies, and transform this data into actionable insights. This comprehensive analysis aims to provide a roadmap for future continuous BioMEMS sensing, revealing the potential unlocked by combining materials science, energy harvesting, and artificial intelligence. Full article
Show Figures

Figure 1

42 pages, 28030 KiB  
Article
Can AI and Urban Design Optimization Mitigate Cardiovascular Risks Amid Rapid Urbanization? Unveiling the Impact of Environmental Stressors on Health Resilience
by Mehdi Makvandi, Zeinab Khodabakhshi, Yige Liu, Wenjing Li and Philip F. Yuan
Sustainability 2025, 17(15), 6973; https://doi.org/10.3390/su17156973 (registering DOI) - 31 Jul 2025
Abstract
In rapidly urbanizing environments, environmental stressors—such as air pollution, noise, heat, and green space depletion—substantially exacerbate public health burdens, contributing to the global rise of non-communicable diseases, particularly hypertension, cardiovascular disorders, and mental health conditions. Despite expanding research on green spaces and health [...] Read more.
In rapidly urbanizing environments, environmental stressors—such as air pollution, noise, heat, and green space depletion—substantially exacerbate public health burdens, contributing to the global rise of non-communicable diseases, particularly hypertension, cardiovascular disorders, and mental health conditions. Despite expanding research on green spaces and health (+76.9%, 2019–2025) and optimization and algorithmic approaches (+63.7%), the compounded and synergistic impacts of these stressors remain inadequately explored or addressed within current urban planning frameworks. This study presents a Mixed Methods Systematic Review (MMSR) to investigate the potential of AI-driven urban design optimizations in mitigating these multi-scalar environmental health risks. Specifically, it explores the complex interactions between urbanization, traffic-related pollutants, green infrastructure, and architectural intelligence, identifying critical gaps in the integration of computational optimization with nature-based solutions (NBS). To empirically substantiate these theoretical insights, this study draws on longitudinal 24 h dynamic blood pressure (BP) monitoring (3–9 months), revealing that chronic exposure to environmental noise (mean 79.84 dB) increases cardiovascular risk by approximately 1.8-fold. BP data (average 132/76 mmHg), along with observed hypertensive spikes (systolic > 172 mmHg, diastolic ≤ 101 mmHg), underscore the inadequacy of current urban design strategies in mitigating health risks. Based on these findings, this paper advocates for the integration of AI-driven approaches to optimize urban environments, offering actionable recommendations for developing adaptive, human-centric, and health-responsive urban planning frameworks that enhance resilience and public health in the face of accelerating urbanization. Full article
(This article belongs to the Section Sustainable Urban and Rural Development)
Show Figures

Figure 1

Back to TopTop