In this paper, we introduce a piezoelectric sensor curled on a thread core in a helical structure. In particular, a polyvinylidene fluoride film was curled and fixed on a thread core. A series of experiments were designed to deliver flexural loading...
This study investigates the downstream wake characteristics of a helical hydrokinetic turbine through combined experimental and numerical analyses. A four-bladed helical turbine with a 20 cm rotor diameter and blockage ratio of 53.57% was tested in a...
Chiral nematic liquid crystals (CLCs), with a unique helix structure, have attracted immense recognition over the last few decades owing to the abundant presence in natural phenomena and their diverse applications. However, the optical properties of...
In tube electrode high-speed electrochemical discharge machining (TSECDM), mixed products are constantly produced in the narrow machining gap by simultaneous discharge erosion and electrochemical dissolution. For the high-efficiency removal of these...
Helical structures are ubiquitous in natural and engineered systems across multiple length scales. Examples include DNA molecules, plants’ tendrils, sea snails’ shells, and spiral nanoribbons. Although this symmetry-breaking shape has sho...
Magnetic soft microrobots have a wide range of applications in targeted drug therapy, cell manipulation, and other aspects. Currently, the research on magnetic soft microrobots is still in the exploratory stage, and most of the research focuses on a...
To optimize the electromagnetic and mechanical properties, a resin-based coating with a bionic helical structure made by carbonyl iron fibers (CIF) was prepared by alternating spray and brushing with 0°/45°/90°. The morphologies of CIP an...
(1) Background: Medical devices, especially neuromodulation devices, are often explanted for a variety of reasons. The removal process imparts significant forces on these devices, which may result in device fracture and tissue trauma. We hypothesized...
Breast-milk αS1-casein is a Toll-like receptor 4 (TLR4) agonist, whereas phosphorylated αS1-casein does not bind TLR4. The objective of this study was to analyse the structural requirements for these effects. In silico analysis of αS1-casein indicate...
Untethered microrobots provide the prospect for performing minimally invasive surgery and targeted delivery of drugs in hard-to-reach areas of the human body. Recently, inspired by the way the prokaryotic flagella rotates to drive the body forward, n...
As a high-performance innovative fuel rod design, helical cruciform fuel (HCF) exhibits significant advantages over conventional circular fuel rods, such as a larger heat transfer area per unit volume, enhanced fluid flow and heat transfer characteri...
The lightweight property of helical composite spring (HCS) applied in the transportation field has attracted more and more attention recently. However, it is difficult to maintain stiffness and fatigue resistance at the same time. Herein, inspired by...
In developing spacecraft dust environment testing equipment, cyclone separators serve as critical particulate separation devices. To optimize cyclone performance, this study investigates the impact of inlet configurations on internal flow fields. We...
A large portion of proteins in living organisms are membrane proteins which play critical roles in the biology of the cell, from maintenance of the biological membrane integrity to communication of cells with their surroundings. To understand their m...
Protein structure is invariably connected to protein function. There are two important secondary structure elements: alpha-helices and beta-sheets (which sometimes come in a shape of beta-barrels). The actual shapes of these structures can be complic...
A fiber-optic torsion sensor based on a helical two-core fiber (HTCF) is proposed and experimentally demonstrated for simultaneously measuring torsion angle and torsion direction. The sensor consists of a segment of HTCF and two single-mode fibers (S...
Much attention has recently focused on helical structures that can change their helicity in response to external stimuli. The requirements for the invertible helical structures are a dynamic feature and well-defined structures. In this context, helic...
The inherent trade-off between strength and toughness in structural materials remains a critical challenge. Inspired by the hierarchical architecture of fish scales, this study proposes a novel overlapping helical composite structure. Multi-material...
We report the crystal structure and bioinformatic analysis of SF173, a functionally uncharacterized protein from the human enteropathogenic bacteria Shigella flexneri. The structure shows a tightly interlinked dimer formed by adimeric core comprising...
Chemically modified nucleobases are thought to be important for therapeutic purposes as well as diagnosing genetic diseases and have been widely involved in research fields such as molecular biology and biochemical studies. Many artificially modified...
High-voltage overhead power lines consist of the non-insulated, densely packed round or trapezoidal aluminum strands supported by a reinforced core. This configuration may ensure the acceptable investment cost, mass per unit length, and aerodynamic e...
Cholesteric liquid crystals (CLCs) are sensitive to environmental temperature changes, and have been employed as a specific intermediary for biosensors. Considering the temperature-dependent structural changes of CLCs, this study aimed to determine t...
Recombinant elastase strain K overexpressed from E. coli KRX/pCon2(3) was purified to homogeneity by a combination of hydrophobic interaction chromatography and ion exchange chromatography, with a final yield of 48% and a 25-fold increase in specific...
The multiple structures of xylem vessels in Magnolia provide stable and efficient water transport channels. The structural parameters of xylem vessels were studied in wood sections and in macerated materials. The results showed that the xylem vessels...
The brittleness of alginate fibers has limited their biological applications. Enhancing fiber toughness without sacrificing fracture tensile strength is challenging. Herein, an acidity-triggered helical conformational change in alginate is demonstrat...
In this study, three-dimensional finite element models of high-mast light poles without and with spiral helical strakes were built using ANSYS software to investigate their vibration characteristics in a wind environment. Based on a two-way, fluid&nd...
In this study we consider the features of spatial-structure formation in proteins and their application in bioengineering. Methods for the quantitative assessment of the chirality of regular helical and irregular structures of proteins are presented....
Electrochemical discharge machining (ECDM) is one effective way to fabricate non-conductive materials, such as quartz glass and ceramics. In this paper, the mathematical model for the machining process of ECDM was established. Then, sets of experimen...
In an effort to develop short antimicrobial peptides with simple amino acid compositions, we generated a series of undecapeptide isomers having the L5K5W formula. Amino acid sequences were designed to be perfectly amphipathic when folded into a helic...
A wide variety of oligomeric structures are formed during the aggregation of proteins associated with neurodegenerative diseases. Such soluble oligomers are believed to be key toxic species in the related disorders; therefore, identification of the s...
Marine flexible pipe/cables, such as umbilicals, flexible pipes and cryogenic hoses, are widely adopted in ocean engineering. The reinforcing armor layer in these pipe/cables is the main component for bearing loads, which is a typical multi-layer hel...
This study investigated the stability of structural motifs via molecular dynamics, using α-α-corners as an example. A molecular dynamics experiment was performed on a sample of α-α-corners selected by the authors from the PDB database. For the first...
The twist-bend nematic liquid crystal phase is a three-dimensional fluid in which achiral bent molecules spontaneously form an orientationally ordered, macroscopically chiral, heliconical winding of a ten nanometer-scale pitch in the absence of posit...
The degeneration of heart valve bioprostheses due to calcification processes is caused by the intercalation of calciumhydroxyapatite in pericardium collagen bundles. Variations of the protein secondary structure of biomaterials according to preparati...
A “foldamer” is an artificial oligomeric molecule with a regular secondary or tertiary structure consisting of various building blocks. A “stapled peptide” is a peptide with stabilized secondary structures, in particular, heli...
Varying the polyethyleneglycol spacer between two (iso)-nicotinic groups of the ligand systems, a large structural variety of silver coordination compounds was obtained, starting with zero-dimensional ring systems, via one-dimensional chains, helices...
Different classes of foldamers, which are synthetic oligomers that adopt well-defined conformations in solution, have been the subject of extensive studies devoted to the elucidation of the forces driving their secondary structures and their potentia...
The influence of combined (helical and pass) rolling on the structure, residual porosity, and microhardness of an AA6082-0.2 wt % Al2O3 composite produced by casting with ultrasonic processing was evaluated in comparison with the matrix alloy. The na...
Solitary wasps use their stinging venoms for paralyzing insect or spider prey and feeding them to their larvae. We have surveyed bioactive substances in solitary wasp venoms, and found antimicrobial peptides together with some other bioactive peptide...
In the electrochemical machining (ECM) of variable-pitch internal helical grooves, a conventional integral cathode is subject to a kinematic constraint: the working teeth are rigidly fixed to the cathode body and therefore cannot follow a helix angle...
Allosteric modulators have emerged with many potential pharmacological advantages as they do not compete the binding of agonist or antagonist to the orthosteric sites but ultimately affect downstream signaling. To identify allosteric modulators targe...
Knowing the eutectic composition of the binary melting point phase diagrams of the diastereomeric salts formed during the given resolution, the achievable F (F = eeDia*Y) value can be calculated. The same value can also be calculated and predicted by...
Cell-penetrating peptides (CPPs) are widely used for the intracellular delivery of a variety of cargo molecules, including small molecules, peptides, nucleic acids, and proteins. Many cationic and amphiphilic CPPs have been developed; however, there...
New advances in protein post-translational modifications (PTMs) have revealed a complex layer of regulatory mechanisms through which PTMs control cell signaling and metabolic pathways, contributing to the diverse metabolic phenotypes found in cancer....
Magainin 2 (Mag2), which was isolated from the skin of the African clawed frog, is a representative antimicrobial peptide (AMP) that exerts antimicrobial activity via microbial membrane disruption. It has been reported that the helicity and amphipath...
Commentary on Ge, P.; Tsao, J.; Schein, S.; Green, T.J.; Luo, M.; Zhou, Z.H. Cryo-EM model of the bullet-shaped vesicular stomatitis virus. Science 2010, 327, 689-693.
We provide an overview of the helical magnetic structures in magnetic microwires. Having analyzed the experimental data describing the magnetic behavior of magnetic microwires since the 1990s, we found indirect evidence of the existence of various ty...
The quantitative evaluation of the chirality of macromolecule structures remains one of the exciting issues in biophysics. In this paper, we propose methods for quantitative analysis of the chirality of protein helical and superhelical structures. Th...
The Boerdijk–Coxeter helix is a helical structure of tetrahedra which possesses no non-trivial translational or rotational symmetries. In this document, we develop a procedure by which this structure is modified to obtain both translational and...
Does a similar 3D structure mean a similar folding pathway? This question is particularly meaningful when it concerns proteins sharing a similar 3D structure, but low sequence identity or homology. MAX effectors secreted by the phytopathogenic fungus...
of 37