Skip to Content
You are currently on the new version of our website. Access the old version .

11,439 Results Found

  • Article
  • Open Access
74 Citations
6,203 Views
18 Pages

29 January 2019

Kaempferia galanga and Kaempferia elegans, which belong to the genus Kaempferia family Zingiberaceae, are used as valuable herbal medicine and ornamental plants, respectively. The chloroplast genomes have been used for molecular markers, species iden...

  • Article
  • Open Access
32 Citations
4,221 Views
14 Pages

Comparative Analysis of Full Genome Sequences of African Swine Fever Virus Isolates Taken from Wild Boars in Russia in 2019

  • Ali Mazloum,
  • Antoinette van Schalkwyk,
  • Andrey Shotin,
  • Alexey Igolkin and ,
  • Ivan Shevchenko,
  • Konstantin N. Gruzdev and
  • Natalia Vlasova
  • + 2 authors+ 0 author

In this study, we report on the full genome phylogenetic analysis of four ASFV isolates obtained from wild boars in Russia. These samples originated from two eastern and two western regions of Russia in 2019. Phylogenetic analysis indicated that the...

(This article belongs to the Special Issue African Swine Fever: Epidemiology, Design of New Diagnostic Methods and Vaccine Development)
  • Article
  • Open Access
5 Citations
3,575 Views
13 Pages

Comparative Analysis and Phylogenetic Study of the Chloroplast Genome Sequences of Two Korean Endemic Primula Varieties

  • Sang-Chul Kim,
  • Young-Ho Ha,
  • Dong-Kap Kim,
  • Dong Chan Son and ,
  • Hyuk-Jin Kim and
  • Kyung Choi
  • + 1 author+ 0 author

7 June 2022

Primula comprises many species of horticultural value. In Korea, six species grow in the wild. Yamazaki classified the variety Primula modesta var. fauriei into P. modesta var. hannasanensis and P. modesta var. koreana based on the differences in lea...

  • Article
  • Open Access
2 Citations
2,514 Views
19 Pages

Whole Genome Sequencing and Comparative Genomics Analysis of Goat-Derived Klebsiella oxytoca

  • Yu Zhang,
  • Zhenxing Zhang,
  • Ziying Wang,
  • Yimei Chen and ,
  • Lianjie Liao,
  • Li Du,
  • Hongyan Gao,
  • Qiaoling Chen,
  • Churiga Man and
  • Fengyang Wang
  • + 6 authors+ 1 author

26 December 2024

Background: This research aims to enhance the genomic database of Klebsiella oxytoca by identifying virulence genes through the whole genome sequencing and comparative analysis of a goat-derived K. oxytoca (KOHN1) strain, while clarifying the relatio...

(This article belongs to the Special Issue Advances in Molecular Microbiology, Genetics, and Bioinformatics of Multiple-Drug-Resistant Bacteria in Public Health)
  • Article
  • Open Access
14 Citations
3,680 Views
19 Pages

Assembly and Annotation of Red Spruce (Picea rubens) Chloroplast Genome, Identification of Simple Sequence Repeats, and Phylogenetic Analysis in Picea

  • Rajni Parmar,
  • Federica Cattonaro,
  • Carrie Phillips,
  • Serguei Vassiliev and ,
  • Michele Morgante and
  • Om P. Rajora
  • + 1 author+ 0 author

3 December 2022

We have sequenced the chloroplast genome of red spruce (Picea rubens) for the first time using the single-end, short-reads (44 bp) Illumina sequences, assembled and functionally annotated it, and identified simple sequence repeats (SSRs). The contigs...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
1 Citations
2,056 Views
12 Pages

A comprehensive overview of the recent physics-inspired genome analysis tool, GenomeBits, is presented. This is based on traditional signal processing methods such as discrete Fourier transform (DFT). GenomeBits can be used to extract underlying geno...

(This article belongs to the Special Issue New Knowledge in the Study of Coronaviruses: Towards One Health and Whole Genome Sequencing Approaches)
  • Article
  • Open Access
4 Citations
2,526 Views
18 Pages

Isolation of a Virulent Clostridium perfringens Strain from Elaphurus davidianus and Characterization by Whole-Genome Sequence Analysis

  • Zhao Zhang,
  • Xiao Wang,
  • Siyuan Li,
  • Yuhang Fu and ,
  • Yan Li,
  • Shah Nawaz,
  • Jing Chen,
  • Guoxiang Yang,
  • Jiakui Li and
  • Daoliang Shi
  • + 5 authors+ 0 author

Clostridium perfringens (C. perfringens) is an important veterinary pathogen and a noteworthy threat to human and animal health. Recently, there has been a significant rise in the number of moose fatalities caused by this rare, endemic species in Chi...

(This article belongs to the Collection Feature Papers Collection in Molecular Microbiology)
  • Article
  • Open Access
7 Citations
2,438 Views
12 Pages

26 April 2024

Kohlrabi is an important swollen-stem cabbage variety belonging to the Brassicaceae family. However, few complete chloroplast genome sequences of this genus have been reported. Here, a complete chloroplast genome with a quadripartite cycle of 153,364...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
2,015 Views
16 Pages

Whole-Genome Sequencing and Comparative Genomic Analysis of Three Clinical Bloodstream Infection Isolates of Trichosporon austroamericanum

  • Takanori Horiguchi,
  • Takashi Umeyama,
  • Hiroko Tomuro,
  • Amato Otani and ,
  • Takayuki Shinohara,
  • Masahiro Abe,
  • Shogo Takatsuka,
  • Ken Miyazawa,
  • Minoru Nagi and
  • Yoshitsugu Miyazaki
  • + 14 authors+ 9 authors

21 May 2025

Trichosporon austroamericanum is a recently described yeast species related to Trichosporon inkin and exclusively isolated from clinical specimens. However, its genomic features and pathogenic potential remain poorly understood. In this study, we per...

(This article belongs to the Section Fungal Genomics, Genetics and Molecular Biology)
  • Article
  • Open Access
12 Citations
3,614 Views
15 Pages

Complete Mitochondrial Genome Sequence, Characteristics, and Phylogenetic Analysis of Oenanthe javanica

  • Xiaoyan Li,
  • Qiuju Han,
  • Mengyao Li,
  • Qing Luo and ,
  • Shunhua Zhu,
  • Yangxia Zheng and
  • Guofei Tan
  • + 2 authors+ 0 author

10 August 2023

The plant mitochondria play a crucial role in various cellular energy synthesis and conversion processes and are essential for plant growth. Watercress (Oenanthe javanica) is a fast-growing vegetable with strong adaptability and wide cultivation rang...

(This article belongs to the Special Issue Smart Strategies and Technologies for Sustainability and Biodiversity in Herbaceous and Horticultural Crops)
  • Article
  • Open Access
14 Citations
4,183 Views
13 Pages

Whole Genomic Sequence Analysis of Human Adenovirus Species C Shows Frequent Recombination in Tianjin, China

  • Yue Lei,
  • Zhichao Zhuang,
  • Yang Liu,
  • Zhaolin Tan and ,
  • Xin Gao,
  • Xiaoyan Li and
  • Dongjing Yang
  • + 2 authors+ 0 author

19 April 2023

Human adenovirus species C (HAdV-C) is frequently detected in China and worldwide. For the first time, 16 HAdV-C strains were isolated from sewage water (14 strains) and hospitalised children with diarrhoea (2 strains,) in Tianjin, China. Nearly comp...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Communication
  • Open Access
11 Citations
6,002 Views
9 Pages

Complete Genome Sequence Analysis of the First Imported Mpox Virus Clade Ib Variant in China

  • Yin Song,
  • Yong Yan,
  • Jingyu Xu,
  • Shencong Lv and ,
  • Ganglin Ren,
  • Yamei Zhou,
  • Wanchen Song,
  • Rui Ge,
  • Peihua Xu and
  • Zhongwen Chen
  • + 6 authors+ 1 author

20 January 2025

Mpox, a zoonotic disease caused by the mpox virus (MPXV), has seen a significant shift in its epidemiological status since 2022, evolving from an initial local outbreak to a global epidemic. This recent outbreak of MPXV mainly emerged in several Euro...

  • Article
  • Open Access
8 Citations
3,786 Views
15 Pages

Analysis of the Selection Signal of the Tibetan Black Chicken Genome Based on Whole-Genome Sequencing

  • Jing Feng,
  • Wei Zhu,
  • Hairen Shi,
  • Da Peng and ,
  • Lei Zang,
  • Yan Wang,
  • Luobu ZhaXi,
  • Jiancai BaiMa,
  • Felix Kwame Amevor and
  • Xiaoling Zhao
  • + 7 authors+ 2 authors

24 August 2023

Background: The Tibetan chicken has adapted well to high altitudes genetically after its long-term habitation in the plateau. In this study, we analyzed the selection signal of Tibetan black chickens (TBCs) and discovered genes associated with the ch...

(This article belongs to the Special Issue Poultry Breeding: Genetics and Genomics)
  • Article
  • Open Access
4 Citations
4,560 Views
17 Pages

Comparative Pan-Genomic Analysis Revealed an Improved Multi-Locus Sequence Typing Scheme for Staphylococcus aureus

  • Maira Jalil,
  • Fatima Quddos,
  • Farha Anwer,
  • Samavi Nasir and ,
  • Abdur Rahman,
  • Metab Alharbi,
  • Abdulrahman Alshammari,
  • Huda Kamel Alshammari and
  • Amjad Ali
  • + 4 authors+ 0 author

19 November 2022

The growing prevalence of antibiotic-resistant Staphylococcus aureus strains mandates selective susceptibility testing and epidemiological investigations. It also draws attention to an efficient typing strategy. Whole genome sequencing helps in genet...

(This article belongs to the Section Microbial Genetics and Genomics)
  • Article
  • Open Access
16 Citations
4,098 Views
14 Pages

Whole Genome Sequence Analysis of Brucella abortus Isolates from Various Regions of South Africa

  • Maphuti Betty Ledwaba,
  • Barbara Akorfa Glover,
  • Itumeleng Matle,
  • Giuseppe Profiti and ,
  • Pier Luigi Martelli,
  • Rita Casadio,
  • Katiuscia Zilli,
  • Anna Janowicz,
  • Francesca Marotta and
  • Henriette van Heerden
  • + 6 authors+ 1 author

The availability of whole genome sequences in public databases permits genome-wide comparative studies of various bacterial species. Whole genome sequence-single nucleotide polymorphisms (WGS-SNP) analysis has been used in recent studies and allows t...

(This article belongs to the Special Issue Updates on Brucellosis)
  • Article
  • Open Access
2,553 Views
17 Pages

Whole Genome Sequencing, Comparative Genome Analysis, and Biotechnological Potential of Emericellopsis alkalina and E. fimetaria (Bionectriaceae, Ascomycota) from the Sediment of Alkaline, Saline Lakes

  • Vladimir V. Sokolov,
  • Kseniya V. Malysheva,
  • Elena N. Bilanenko,
  • Natalia N. Markelova and ,
  • Oksana A. Kolpakova,
  • Marina L. Georgieva and
  • Vera S. Sadykova
  • + 2 authors+ 0 author

26 April 2026

Emericellopsis species from extreme environmental conditions provide a rich source of unique and biologically active secondary metabolites. The paper exhibits a comprehensive genomic analysis including complete genome sequencing, phylogenetic reconst...

(This article belongs to the Special Issue Fungal Ecology and Biotechnology Under Extreme Conditions)
  • Communication
  • Open Access
4 Citations
5,379 Views
9 Pages

Whole Genome Sequencing and Phylogenetic Analysis of Rabies Viruses from Bats in Connecticut, USA, 2018–2019

  • Ji-Yeon Hyeon,
  • Guillermo R. Risatti,
  • Zeinab H. Helal,
  • Holly McGinnis and ,
  • Maureen Sims,
  • Amelia Hunt,
  • David H. Chung,
  • Junwon Kim,
  • Julia Desiato and
  • Dong-Hun Lee
  • + 5 authors+ 0 author

13 December 2021

We performed whole genome sequencing and genetic characterization of rabies viruses (RABV) detected in bats submitted to the Connecticut Veterinary Medical Diagnostic Laboratory (CVMDL) during 2018–2019. Among 88 bats submitted to CVMDL, six br...

(This article belongs to the Special Issue Innovative Techniques and Approaches in the Control and Prevention of Rabies Virus)
  • Article
  • Open Access
6 Citations
4,508 Views
10 Pages

Genomic Sequence Analysis of the Multidrug-Resistance Region of Avian Salmonella enterica serovar Indiana Strain MHYL

  • Yan Lu,
  • Yanjia Wen,
  • Ge Hu,
  • Yuqi Liu and ,
  • Ross C. Beier and
  • Xiaolin Hou
  • + 1 author+ 0 author

A series of human and animal diseases that are caused by Salmonella infections pose a serious threat to human health and huge economic losses to the livestock industry. We found antibiotic resistance (AR) genes in the genome of 133 strains of S. Indi...

(This article belongs to the Special Issue Foodborne Pathogen Distribution, Ecology, Inactivation and Methods of Differentiation)
  • Brief Report
  • Open Access
1 Citations
2,862 Views
7 Pages

Novel RAI1:c.2736delC Variant in Smith–Magenis Syndrome: Identification by Whole Genome Sequencing and Joint Analysis

  • Mario Cuk,
  • Busra Unal,
  • Nives Jandric,
  • Connor P. Hayes and ,
  • McKenzie Walker,
  • Feruza Abraamyan,
  • Kristina Crkvenac Gornik and
  • Arezou A. Ghazani
  • + 3 authors+ 0 author

25 August 2024

Smith–Magenis syndrome is a complex neurobehavioral genetic disorder with a broad phenotypic spectrum. While the etiology of SMS is commonly attributed to one-copy interstitial deletion in the 17p11.2 region (90–95% of cases), variants id...

(This article belongs to the Section Personalized Therapy in Clinical Medicine)
  • Article
  • Open Access
11 Citations
3,628 Views
13 Pages

Whole-Genome Sequencing and Drug-Susceptibility Analysis of Serial Mycobacterium abscessus Isolates from Thai Patients

  • Orawee Kaewprasert,
  • Ditthawat Nonghanphithak,
  • Ploenchan Chetchotisakd,
  • Wises Namwat and ,
  • Rick Twee-Hee Ong and
  • Kiatichai Faksri
  • + 1 author+ 0 author

5 September 2022

Mycobacterium abscessus is an important pathogen that can cause serious human diseases and is difficult to treat due to antibiotic resistance. In this study, we analyzed, using whole-genome sequence (WGS) data, M. abscessus strains serially isolated...

(This article belongs to the Section Genetics and Genomics)
  • Article
  • Open Access
10 Citations
4,818 Views
19 Pages

Evaluation and Analysis of Absence of Homozygosity (AOH) Using Chromosome Analysis by Medium Coverage Whole Genome Sequencing (CMA-seq) in Prenatal Diagnosis

  • Yan Lü,
  • Yulin Jiang,
  • Xiya Zhou,
  • Na Hao and ,
  • Guizhen Lü,
  • Xiangxue Guo,
  • Ruidong Guo,
  • Wenjie Liu,
  • Chenlu Xu and
  • Qingwei Qi
  • + 10 authors+ 5 authors

Objective: Absence of homozygosity (AOH) is a genetic characteristic known to cause human diseases mainly through autosomal recessive or imprinting mechanisms. The importance and necessity of accurate AOH detection has become more clinically signific...

(This article belongs to the Special Issue Prenatal Diagnosis: Current Trends and Future Directions)
  • Article
  • Open Access
18 Citations
4,461 Views
13 Pages

Whole-Genome Sequence Analysis of an Endophytic Fungus Alternaria sp. SPS-2 and Its Biosynthetic Potential of Bioactive Secondary Metabolites

  • Jianyun Tao,
  • Xuelian Bai,
  • Mingyuan Zeng,
  • Mengshi Li and ,
  • Zhe Hu,
  • Yunfen Hua and
  • Huawei Zhang
  • + 2 authors+ 0 author

As one of the commonly isolated endophytic fungi, Alternaria has been known for the production of numerous secondary metabolites (SMs). However, its detailed genomic features and SM biosynthetic potential have not been extensively studied thus far. T...

(This article belongs to the Special Issue Secondary Metabolism of Microorganisms 2.0)
  • Article
  • Open Access
1 Citations
1,440 Views
14 Pages

Whole-Genome Sequence Analysis of Shiga Toxin-Producing Escherichia coli Isolated from Livestock Animals in Ghana

  • Yusuke Ota,
  • Samiratu Mahazu,
  • Ivy Brago Amanor,
  • Frederick Ofosu Appiah and ,
  • Jennifer Amedior,
  • Emmanuel Darko,
  • Mitsunori Yoshida,
  • Masato Suzuki,
  • Yoshihiko Hoshino and
  • Ryoichi Saito
  • + 7 authors+ 2 authors

Shiga toxin-producing Escherichia coli (STEC) is a zoonotic pathogen of public health concern, requiring a One Health approach to clarify its transmission and distribution. However, its prevalence and genomic characteristics in livestock and companio...

(This article belongs to the Section Veterinary Microbiology)
  • Feature Paper
  • Article
  • Open Access
3 Citations
2,300 Views
14 Pages

Selection Signature Analysis of Whole-Genome Sequences to Identify Genome Differences Between Selected and Unselected Holstein Cattle

  • Jiarui Cai,
  • Liu Yang,
  • Yahui Gao,
  • George E. Liu and ,
  • Yang Da and
  • Li Ma
  • + 1 author+ 0 author

31 July 2025

A unique line of Holstein cattle has been maintained without selection in Minnesota since 1964. After many generations, unselected cattle produce less milk, but have better reproductive performance and health traits when compared with contemporary co...

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
11 Citations
2,579 Views
12 Pages

The genus Ormosia comprises approximately 130 species, which are found in tropical regions all over the world. The taxonomy and evolutionary history are still ambiguous due to the lack of a solid phylogeny at the species level. Due to the fast advanc...

(This article belongs to the Section Genetics, Genomics, Breeding, and Biotechnology (G2B2))
  • Article
  • Open Access
9 Citations
6,141 Views
17 Pages

Phylogenetic Characterization and Genome Sequence Analysis of Burkholderia glumae Strains Isolated in Thailand as the Causal Agent of Rice Bacterial Panicle Blight

  • Nootjarin Jungkhun,
  • Antonio Roberto Gomes de Farias,
  • Jutatape Watcharachaiyakup,
  • Nuttima Kositcharoenkul and ,
  • Jong Hyun Ham and
  • Sujin Patarapuwadol
  • + 1 author+ 0 author

Burkholderia glumae is one of the most critical rice-pathogenic bacteria, and it causes bacterial panicle blight (BPB) in rice plants. In 2017, BPB symptoms were observed from rice fields in Chiang Rai, Northern Thailand. Sixty-one isolates obtained...

(This article belongs to the Special Issue Plant Pathogenic Bacteria in Crops)
  • Article
  • Open Access
15 Citations
4,930 Views
20 Pages

28 November 2020

Bougainvillea (Nyctaginaceae) is a popular ornamental plant group primarily grown for its striking colorful bracts. However, despite its established horticultural value, limited genomic resources and molecular studies have been reported for this genu...

(This article belongs to the Special Issue Plant Evolution, Systematics, and Chloroplast Genome)
  • Article
  • Open Access
4 Citations
2,993 Views
17 Pages

20 July 2023

Ehretiaceae is a family in the order Boraginales. It contains more than 150 species. The Ehretiaceae classification has remained elusive and changed over time from subfamily to family, or vice versa. In this paper, we sequenced, characterized, and an...

(This article belongs to the Section Genetics and Molecular Biology)
  • Article
  • Open Access
12 Citations
4,436 Views
15 Pages

Source Attribution of Human Campylobacteriosis Using Whole-Genome Sequencing Data and Network Analysis

  • Lynda Wainaina,
  • Alessandra Merlotti,
  • Daniel Remondini,
  • Clementine Henri and ,
  • Tine Hald and
  • Patrick Murigu Kamau Njage
  • + 1 author+ 0 author

Campylobacter spp. are a leading and increasing cause of gastrointestinal infections worldwide. Source attribution, which apportions human infection cases to different animal species and food reservoirs, has been instrumental in control- and evidence...

  • Article
  • Open Access
47 Views
18 Pages

Identifying Genes Conferring Rust Resistance in Adzuki Bean (Vigna angularis) Through Genome-Wide Association Analysis Based on Genotyping-by-Sequencing (GBS)

  • Xiaodan Xu,
  • Zihan Zhang,
  • Ningning Sun,
  • Sian Peng and ,
  • Tangyi Chen,
  • Yanmin Qie,
  • Lige Geng,
  • Shihui Wang,
  • Weina Sun and
  • Jidao Du
  • + 6 authors+ 1 author

5 November 2026

Adzuki bean (Vigna angularis) is an important pulse crop, and rust disease severely restricts its production. Identifying resistance genes is essential for accelerating the development of rust-resistant cultivars through marker-assisted breeding. In...

  • Article
  • Open Access
18 Citations
4,058 Views
12 Pages

Aspergillus Outbreak in an Intensive Care Unit: Source Analysis with Whole Genome Sequencing and Short Tandem Repeats

  • Stephan J. P. Hiel,
  • Amber C. A. Hendriks,
  • Jos J. A. Eijkenboom,
  • Thijs Bosch and ,
  • Jordy P. M. Coolen,
  • Willem J. G. Melchers,
  • Paul Anröchte,
  • Simone M. T. Camps,
  • Paul E. Verweij and
  • Laura van Dommelen
  • + 6 authors+ 1 author

6 January 2024

Whole genome sequencing (WGS) is widely used for outbreak analysis of bacteriology and virology but is scarcely used in mycology. Here, we used WGS for genotyping Aspergillus fumigatus isolates from a potential Aspergillus outbreak in an intensive ca...

(This article belongs to the Section Fungal Genomics, Genetics and Molecular Biology)
  • Article
  • Open Access
6 Citations
4,821 Views
22 Pages

2 February 2025

Nuclear mitochondrial DNA sequences (NUMTs) are mitochondrial DNA fragments in the nuclear genome, and their unclear distribution in Chrysomelidae species hinders the selection of accurate molecular markers for species identification and phylogenetic...

(This article belongs to the Section Insect Molecular Biology and Genomics)
  • Article
  • Open Access
8 Citations
4,750 Views
15 Pages

Analysis of the Whole-Genome Sequences from an Equus Parent-Offspring Trio Provides Insight into the Genomic Incompatibilities in the Hybrid Mule

  • Xiujuan Ren,
  • Yuanyi Liu,
  • Yiping Zhao,
  • Bei Li and ,
  • Dongyi Bai,
  • Gerelchimeg Bou,
  • Xinzhuang Zhang,
  • Ming Du,
  • Xisheng Wang and
  • Manglai Dugarjaviin
  • + 7 authors+ 2 authors

23 November 2022

Interspecific hybridization often shows negative effects on hybrids. However, only a few multicellular species, limited to a handful of plants and animals, have shown partial genetic mechanisms by which hybridization leads to low fitness in hybrids....

(This article belongs to the Special Issue Equine Genetics and Genomics)
  • Article
  • Open Access
1 Citations
1,244 Views
11 Pages

Cytokinins play an important role in plants and are targets of wheat breeding, particularly in terms of flowering and yield. The objective of this study was to determine relative synonymous codon usage (RSCU), molecular weight (g/mol), theoretical is...

(This article belongs to the Special Issue Genes Function and Mechanism Identification in Plant Stress Resistance: 3rd Edition)
  • Opinion
  • Open Access
18 Citations
5,721 Views
12 Pages

15 February 2021

Whole genome sequencing (WGS) has arisen as a powerful tool to perform pathogen source tracking in the food industry thanks to several developments in recent years. However, the cost associated to this technology and the degree of expertise required...

(This article belongs to the Section Technologies and Resources for Genetics)
  • Article
  • Open Access
5 Citations
2,583 Views
17 Pages

14 December 2023

The Belian (Eusideroxylon zwageri Teijsm. & Binn.) is a commercially important timber species in Southeast Asia that was listed on the IUCN Red List of threatened species in 1998. Six years ago, we published an article in Genome Biology Ecology e...

(This article belongs to the Section Genetics and Molecular Biology)
  • Article
  • Open Access
3,735 Views
31 Pages

A Method for the Structure-Based, Genome-Wide Analysis of Bacterial Intergenic Sequences Identifies Shared Compositional and Functional Features

  • Leonardo Lenzini,
  • Francesca Di Patti,
  • Roberto Livi,
  • Marco Fondi and ,
  • Renato Fani and
  • Alessio Mengoni
  • + 1 author+ 0 author

22 October 2019

In this paper, we propose a computational strategy for performing genome-wide analyses of intergenic sequences in bacterial genomes. Following similar directions of a previous paper, where a method for genome-wide analysis of eucaryotic Intergenic se...

(This article belongs to the Special Issue Tools for Population and Evolutionary Genetics)
  • Article
  • Open Access
6 Citations
1,308 Views
21 Pages

A Comprehensive Comparative Analysis and Phylogenetic Investigation of the Chloroplast Genome Sequences in Four Astragalus Species

  • Hai-Tao Ma,
  • Qi-Yin Chen,
  • Jie-Hua Rao,
  • Kai-Ling Wang and ,
  • Bei Jiang and
  • Yong-Zeng Zhang
  • + 1 author+ 0 author

Astragalus L. (Fabaceae), the largest plant genus with significant medicinal value, faces critical endangerment of its wild resources and a scarcity of chloroplast genomic data. We sequenced and assembled the complete chloroplast (cp) genomes of four...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
14 Citations
4,192 Views
21 Pages

Comprehensive Comparative Analysis and Development of Molecular Markers for Dianthus Species Based on Complete Chloroplast Genome Sequences

  • Shengnan Lin,
  • Jianyi Liu,
  • Xingqun He,
  • Jie Wang and ,
  • Zehao Wang,
  • Xiaoni Zhang,
  • Manzhu Bao and
  • Xiaopeng Fu
  • + 3 authors+ 0 author

19 October 2022

Dianthus spp. is a genus with high economic and ornamental value in the Caryophyllaceae, which include the famous fresh-cut carnation and the traditional Chinese herbal medicine, D. superbus. Despite the Dianthus species being seen everywhere in our...

(This article belongs to the Special Issue Advances in Research for Ornamental Plants Breeding)
  • Article
  • Open Access
7 Citations
3,123 Views
13 Pages

The global rise of drug resistant tuberculosis has highlighted the need for improved diagnostic technologies that provide rapid and reliable drug resistance results. Here, we develop and validate a whole genome sequencing (WGS)-based test for identif...

(This article belongs to the Special Issue Microbial Genome Analysis and Interpretation Using Computational Approaches)
  • Article
  • Open Access
23 Citations
4,509 Views
16 Pages

Analysis of Whole-Genome Sequences of Infectious laryngotracheitis Virus Isolates from Poultry Flocks in Canada: Evidence of Recombination

  • Ana Perez Contreras,
  • Frank van der Meer,
  • Sylvia Checkley,
  • Tomy Joseph and ,
  • Robin King,
  • Madhu Ravi,
  • Delores Peters,
  • Kevin Fonseca,
  • Carl A. Gagnon and
  • Mohamed Faizal Abdul-Careem
  • + 7 authors+ 2 authors

12 November 2020

Infectious laryngotracheitis virus (ILTV) is a herpes virus that causes an acute respiratory disease of poultry known as infectious laryngotracheitis (ILT). Chicken embryo origin (CEO) and tissue culture origin (TCO) live attenuated vaccines are rout...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
16 Citations
4,436 Views
18 Pages

Whole-Genome Sequencing and Transcriptome Analysis of Ganoderma lucidum Strain Yw-1-5 Provides New Insights into the Enhanced Effect of Tween80 on Exopolysaccharide Production

  • Tuheng Wu,
  • Manjun Cai,
  • Huiping Hu,
  • Chunwei Jiao and ,
  • Zhi Zhang,
  • Yuanchao Liu,
  • Jian Chen,
  • Chun Xiao,
  • Xiangmin Li and
  • Yizhen Xie
  • + 8 authors+ 3 authors

14 October 2022

Ganoderma lucidum is an important medicinal mushroom widely cultured in Asian countries. Exopolysaccharides are bioactive compounds of G. lucidum with health benefits. Limited exopolysaccharide content hinders its extraction from G. lucidum. The addi...

(This article belongs to the Special Issue Biotechnology of Edible Fungi)
  • Article
  • Open Access
38 Citations
8,804 Views
18 Pages

K-mer Content, Correlation, and Position Analysis of Genome DNA Sequences for the Identification of Function and Evolutionary Features

  • Aaron Sievers,
  • Katharina Bosiek,
  • Marc Bisch,
  • Chris Dreessen and ,
  • Jascha Riedel,
  • Patrick Froß,
  • Michael Hausmann and
  • Georg Hildenbrand
  • + 3 authors+ 0 author

19 April 2017

In genome analysis, k-mer-based comparison methods have become standard tools. However, even though they are able to deliver reliable results, other algorithms seem to work better in some cases. To improve k-mer-based DNA sequence analysis and compar...

(This article belongs to the Section Technologies and Resources for Genetics)
  • Article
  • Open Access
5 Citations
3,463 Views
14 Pages

Orientia tsutsugamushi is an obligate intracellular bacterium associated with trombiculid mites and is the causative agent of scrub typhus, a life-threatening febrile disease. Strain typing of O. tsutsugamushi is based on its immunodominant surface a...

(This article belongs to the Special Issue Latest Updates on Scrub Typhus (Orientia spp.))
  • Article
  • Open Access
18 Citations
6,952 Views
13 Pages

The Complete Mitochondrial Genome Sequences of the Philomycus bilineatus (Stylommatophora: Philomycidae) and Phylogenetic Analysis

  • Tiezhu Yang,
  • Guolyu Xu,
  • Bingning Gu,
  • Yanmei Shi and ,
  • Hellen Lucas Mzuka and
  • Heding Shen
  • + 1 author+ 0 author

5 March 2019

The mitochondrial genome (mitogenome) can provide information for phylogenetic analyses and evolutionary biology. We first sequenced, annotated, and characterized the mitogenome of Philomycus bilineatus in this study. The complete mitogenome was 14,3...

(This article belongs to the Special Issue Mitochondrial Genomes: Genetic and Transcriptomic Studies)
  • Article
  • Open Access
3 Citations
3,282 Views
17 Pages

Copy Number Variants of Uncertain Significance by Chromosome Microarray Analysis from Consecutive Pediatric Patients: Reevaluation Following Current Guidelines and Reanalysis by Genome Sequencing

  • Wenjiao Li,
  • Xiaolei Xie,
  • Hongyan Chai,
  • Autumn DiAdamo and ,
  • Emily Bistline,
  • Peining Li,
  • Yuan Dai,
  • James Knight,
  • Abraham Joseph Avni-Singer and
  • Jiadi Wen
  • + 9 authors+ 4 authors

24 July 2025

Background: Copy number variants of uncertain significance (CNVus) from chromosome microarray analysis (CMA) presents unresolved challenges for clinical geneticists, genetic counselors, and patients. We performed a systematic reevaluation of reported...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
3 Citations
2,599 Views
16 Pages

Idiopathic superior oblique muscle palsy is a major type of paralytic, non-comitant strabismus and presents vertical and cyclo-torsional deviation of one eye against the other eye, with a large vertical fusion range and abnormal head posture such as...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
7 Citations
3,210 Views
11 Pages

Analysis of Powassan Virus Genome Sequences from Human Cases Reveals Substantial Genetic Diversity with Implications for Molecular Assay Development

  • Erik H. Klontz,
  • Navid Chowdhury,
  • Nolan Holbrook,
  • Isaac H. Solomon and ,
  • Sam R. Telford,
  • Matthew T. Aliota,
  • Chantal B. F. Vogels,
  • Nathan D. Grubaugh,
  • Jeffrey Helgager and
  • John A. Branda
  • + 10 authors+ 5 authors

23 October 2024

Powassan virus (POWV) is an emerging tick-borne virus that causes severe meningoencephalitis in the United States, Canada, and Russia. Serology is generally the preferred diagnostic modality, but PCR on cerebrospinal fluid, blood, or urine has an imp...

(This article belongs to the Special Issue Tick-Borne Viruses: Transmission and Surveillance)
  • Article
  • Open Access
24 Citations
6,796 Views
20 Pages

Seventeen Ustilaginaceae High-Quality Genome Sequences Allow Phylogenomic Analysis and Provide Insights into Secondary Metabolite Synthesis

  • Lena Ullmann,
  • Daniel Wibberg,
  • Tobias Busche,
  • Christian Rückert and ,
  • Andreas Müsgens,
  • Jörn Kalinowski and
  • Lars M. Blank
  • + 2 authors+ 0 author

8 March 2022

The family of Ustilaginaceae belongs to the order of Basidiomycetes. Despite their plant pathogenicity causing, e.g., corn smut disease, they are also known as natural producers of value-added chemicals such as extracellular glycolipids, organic acid...

(This article belongs to the Special Issue Smut Fungi 2.0)
  • Systematic Review
  • Open Access
606 Views
15 Pages

Whole-genome sequencing (WGS) is an increasingly adopted platform for predicting drug resistance in Mycobacterium tuberculosis; however, diagnostic accuracy varies substantially across bioinformatic tools and analytical frameworks, generating conside...

(This article belongs to the Section Public Health Microbiology)

of 229