In this paper, a scheme for generating high-quality tunable microwave-frequency combs (MFCs) is proposed. The proposed scheme is based on an initially non-flat MFC generated by a directly modulated laser operating in gain-switching status. Filtering...
Improvement of antiretroviral therapy (ART) regimen switching practices and implementation of pretreatment drug resistance (PDR) testing are two potential approaches to improve health outcomes for children living with HIV. We developed a microsimulat...
Many companies switched to working from home (WFH) after the COVID-19 pandemic. This paper aimed to examine the changes in dietary behavior, body weight, sedentary lifestyle, and stress in individuals who practice WFH. A cross-sectional, web-based qu...
The aim of the present study was to determine the efficacy and safety of intravitreal brolucizumab therapy for neovascular age-related macular degeneration (AMD) in the real-world setting. The REBA study (real-world experience with brolucizumab in we...
Background: Bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC/FTC/TAF) is a recommended once-daily single-tablet regimen for the treatment of people living with HIV (PLWH). We aimed to assess efficacy, safety, and tolerability of BIC/FTC/...
Automated safety monitoring on construction sites requires precise helmet-status detection and robust multi-object tracking in long, occlusion-rich video sequences. This study proposes a two-stage framework: (i) a YOLOv5 model enhanced with self-adap...
p53 protein is a well-known tumor suppressor factor that regulates cellular homeostasis. As it has several and key functions exerted, p53 is known as “the guardian of the genome” and either loss of function or gain of function mutations in the TP53 c...
Heterotrimeric guanine nucleotide-binding proteins (G proteins) are among the most important cellular signaling components, especially G protein-coupled receptors (GPCRs). G proteins comprise three subunits, Gα, Gβ, and Gγ. Gα...
This paper introduces a high-efficiency buck converter designed for a wide load range, targeting low-power applications in medical devices, smart homes, wearables, IoT, and technology utilizing WiFi and Bluetooth. To achieve high efficiency across va...
In this paper, we explore users’ intentions to use bike-sharing systems (BSS) compared to traditional competitive transport modes—private car, bus and walking. Fueled by the increasingly rampant growth of shared economy and Information an...
In this paper we summarize the status of bifacial photovoltaics (PV) and explain why the move to bifaciality is unavoidable when it comes to e.g., lowest electricity generation costs or agricultural PV (AgriPV). Bifacial modules—those that are sensit...
The advent of effective antiretroviral therapy in the mid-1990s, which successfully prevented the progression to AIDS in people living with HIV (PLWH), was associated with the appearance of the so-called HIV-associated lipodystrophy. This condition i...
Acoustic coupling between microphone and loudspeaker is a significant problem in open-fit digital hearing aids. An open-fit compared to a close-fit hearing aid significantly lowers the signal quality and limits the achievable maximum stable gain. Ada...
Aim: To develop a microsimulation model to assess the potential health economic impact of software-assisted MRI in detecting disease activity or progression in relapsing-remitting multiple sclerosis (RRMS) patients. Methods: We develop a simulated de...
Anaplastic lymphoma kinase-rearranged non-small-cell lung cancer (ALK+ NSCLC) is a model disease for the use of targeted pharmaceuticals in thoracic oncology. Due to higher systemic and intracranial efficacy, the second-generation ALK tyrosine kinase...
In recent years, agricultural production activities have been advancing towards mechanization and intelligence to bridge the growing gap between the high labor intensity and time sensitivity of harvesting operations and the limited labor resources. A...