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Search Results (582)

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Keywords = fiber quality measurements

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24 pages, 1604 KiB  
Article
Assessment of Low-Cost Sensors in Early-Age Concrete: Laboratory Testing and Industrial Applications
by Rocío Porras, Behnam Mobaraki, Zhenquan Liu, Thayré Muñoz, Fidel Lozano and José A. Lozano
Appl. Sci. 2025, 15(15), 8701; https://doi.org/10.3390/app15158701 (registering DOI) - 6 Aug 2025
Abstract
Concrete is an essential material in the construction industry due to its strength and versatility. However, its quality can be compromised by environmental factors during its fresh and early-age states. To address this vulnerability, various sensors have been implemented to monitor critical parameters. [...] Read more.
Concrete is an essential material in the construction industry due to its strength and versatility. However, its quality can be compromised by environmental factors during its fresh and early-age states. To address this vulnerability, various sensors have been implemented to monitor critical parameters. While high-precision sensors (e.g., piezoelectric and fiber optic) offer accurate measurements, their cost and fragility limit their widespread use in construction environments. In response, this study proposes a cost-effective, Arduino-based wireless monitoring system to track temperature and humidity in fresh and early-age concrete elements. The system was validated through laboratory tests on cylindrical specimens and industrial applications on self-compacting concrete New Jersey barriers. The sensors recorded temperature variations between 15 °C and 35 °C and relative humidity from 100% down to 45%, depending on environmental exposure. In situ monitoring confirmed the system’s ability to detect thermal gradients and evaporation dynamics during curing. Additionally, the presence of embedded sensors caused a tensile strength reduction of up to 37.5% in small specimens, highlighting the importance of sensor placement. The proposed solution demonstrates potential for improving quality control and curing management in precast concrete production with low-cost devices. Full article
29 pages, 4763 KiB  
Review
Quantum-Empowered Fiber Sensing Metrology
by Xiaojie Zuo, Zhangguan Tang, Boyao Li, Xiaoyong Chen and Jinghua Sun
Photonics 2025, 12(8), 763; https://doi.org/10.3390/photonics12080763 - 29 Jul 2025
Viewed by 351
Abstract
Quantum sensing leverages quantum resources to enable ultra-precise measurements beyond classical limits, driving transformative advancements in metrology. Optical fiber quantum sensing, integrating optical fiber sensing with quantum technologies, enhances measurement precision and sensitivity from multiple perspectives, such as exploring high-sensitivity optical fiber sensing [...] Read more.
Quantum sensing leverages quantum resources to enable ultra-precise measurements beyond classical limits, driving transformative advancements in metrology. Optical fiber quantum sensing, integrating optical fiber sensing with quantum technologies, enhances measurement precision and sensitivity from multiple perspectives, such as exploring high-sensitivity optical fiber sensing installations and generating high-quality optical fiber quantum states. Following decades of comprehensive investigations and remarkable advances in optical fiber quantum sensing technology, this review systematically examines research achievements in this field through two complementary perspectives: one is the basic principle of generating optical fiber quantum states and their applications in sensing and the other is optical fiber quantum interferometers and their applications in sensing. Finally, examine current opportunities and challenges as well as the future development of optical fiber quantum sensing. Full article
(This article belongs to the Special Issue Quantum High Precision Measurement)
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22 pages, 1513 KiB  
Article
Forage Yield, Quality, and Weed Suppression in Narbon Vetch (Vicia narbonensis L.) and Italian Ryegrass (Lolium multiflorum L.) Mixtures Under Organic Management
by Melek Demircan, Emine Serap Kizil Aydemir and Koray Kaçan
Agronomy 2025, 15(8), 1796; https://doi.org/10.3390/agronomy15081796 - 25 Jul 2025
Viewed by 192
Abstract
This study aimed to evaluate the forage yield, quality, and weed suppression potential of narbon vetch (Vicia narbonensis L.) and Italian ryegrass (Lolium multiflorum L.) grown as sole crops and in mixtures under organic farming conditions in Bilecik, Turkey, during the [...] Read more.
This study aimed to evaluate the forage yield, quality, and weed suppression potential of narbon vetch (Vicia narbonensis L.) and Italian ryegrass (Lolium multiflorum L.) grown as sole crops and in mixtures under organic farming conditions in Bilecik, Turkey, during the 2020–2021 growing season. The experiment included 15 treatments comprising monocultures and mixed sowing at different ratios. Measurements included morphological traits, forage yield components (green herbage, hay, and crude protein), fiber content, botanical composition, and weed biomass. The results reveal significant differences among treatments in terms of growth parameters and forage performance. Monocultures of IFVN 567 and Bartigra showed the highest green and hay yields, while mixtures such as IFVN 567 + Trinova and IFVN 567 + Bartigra outperformed in terms of land equivalent ratio (LER) and protein yield, demonstrating a clear advantage in land use efficiency. Furthermore, these mixtures showed superior weed suppression compared to monocultures. Overall, the findings suggest that carefully selected vetch–ryegrass combinations can enhance forage productivity, nutritional quality, and weed management under organic systems. Full article
(This article belongs to the Section Grassland and Pasture Science)
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22 pages, 5356 KiB  
Article
Seaweed, Used as a Water-Retaining Agent, Improved the Water Distribution and Myofibrillar Protein Properties of Plant-Based Yak Meat Burgers Before and After Freeze–Thaw Cycles
by Yujiao Wang, Xinyi Chang, Yingzhen Wang, Jiahao Xie, Ge Han and Hang Qi
Foods 2025, 14(14), 2541; https://doi.org/10.3390/foods14142541 - 21 Jul 2025
Viewed by 415
Abstract
This study investigated quality changes in seaweed–yak patties before and after freeze–thaw by varying seaweed addition levels (10–70%). Macroscopically, the effects on water-holding capacity, textural properties, and oxidative indices of restructured yak patties were evaluated. Microscopically, the impact of seaweed-derived bioactive ingredients on [...] Read more.
This study investigated quality changes in seaweed–yak patties before and after freeze–thaw by varying seaweed addition levels (10–70%). Macroscopically, the effects on water-holding capacity, textural properties, and oxidative indices of restructured yak patties were evaluated. Microscopically, the impact of seaweed-derived bioactive ingredients on patty microstructure and myofibrillar protein characteristics was examined. LF-NMR and MRI showed that 40% seaweed addition most effectively restricted water migration, reduced thawing loss, and preserved immobilized water content. Texture profile analysis (TPA) revealed that moderate seaweed levels (30–40%) enhanced springiness and minimized post-thaw hardness increases. SEM confirmed that algal polysaccharides formed a denser protective network around the muscle fibers. Lipid oxidation (MDA), free-radical measurements, and non-targeted metabolomics revealed a significant reduction in oxidative damage at 40% seaweed addition, correlating with increased total phenolic content. Protein analyses (particle size, zeta potential, hydrophobicity, and SDS-PAGE) demonstrated a cryoprotective effect of seaweed on myofibrillar proteins, reducing aggregation and denaturation. These findings suggest that approximately 40% seaweed addition can improve the physicochemical stability and antioxidant capacity of frozen seaweed–yak meat products. This work thus identifies the optimal seaweed addition level for enhancing freeze–thaw stability and functional quality, offering practical guidance for the development of healthier, high-value restructured meat products. Full article
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13 pages, 380 KiB  
Article
Association Between Carbohydrate Quality Index During Pregnancy and Risk for Large-for-Gestational-Age Neonates: Results from the BORN 2020 Study
by Antigoni Tranidou, Antonios Siargkas, Ioannis Tsakiridis, Emmanouela Magriplis, Aikaterini Apostolopoulou, Michail Chourdakis and Themistoklis Dagklis
Children 2025, 12(7), 955; https://doi.org/10.3390/children12070955 - 20 Jul 2025
Viewed by 283
Abstract
Background/Objectives: To assess the association between early pregnancy carbohydrate quality, as measured by the Carbohydrate Quality Index (CQI), and the risk of delivering a large-for-gestational-age (LGA) infant in a Mediterranean pregnant cohort of northern Greece. Methods: We analyzed singleton pregnancies from [...] Read more.
Background/Objectives: To assess the association between early pregnancy carbohydrate quality, as measured by the Carbohydrate Quality Index (CQI), and the risk of delivering a large-for-gestational-age (LGA) infant in a Mediterranean pregnant cohort of northern Greece. Methods: We analyzed singleton pregnancies from the BORN 2020 prospective cohort in Greece. Dietary intake was assessed via a validated food frequency questionnaire, and CQI was computed from glycemic index, fiber density, whole-to-refined grain ratio, and solid-to-liquid carbohydrate ratio. Multivariable logistic regression was used to estimate the association between CQI (in tertiles) and LGA risk, defined as birthweight >90th percentile. Results: Among the 797 participants, 152 (19.1%) delivered LGA infants, and 117 (14.7%) were diagnosed with GDM. Of those with GDM, 23 (19.7%) delivered LGA infants. In the total population, higher maternal weight (p < 0.001), height (p = 0.006), and pre-pregnancy BMI (p = 0.004) were significantly associated with LGA. A greater proportion of women with LGA had a BMI > 25 (p = 0.007). In the GDM subgroup, maternal height remained significantly higher in those who delivered LGA infants (p = 0.017). In multivariable models, moderate CQI was consistently associated with increased odds of LGA across all models (Model 1: aOR = 1.60 (95% CI: 1.03–2.50), p = 0.037, Model 2: aOR = 1.57 (95% CI: 1.01–2.46), p = 0.046, Model 3: aOR = 1.58 (95% CI: 1.01–2.47), p = 0.044, Model 4 aOR: 1.70; 95% CI: 1.08–2.72; p = 0.023), whereas high CQI was not. In the GDM subgroup, a significant association between high CQI and increased LGA risk was observed in less adjusted models (Model 1 aOR: 6.74; 95% CI: 1.32–56.66; p = 0.039, Model 2 aOR: 6.64; 95% CI: 1.27–57.48; p = 0.044), but this was attenuated and became non-significant in the fully adjusted model (aOR: 3.05; 95% CI: 0.47–30.22; p = 0.28). When examining CQI components individually, no consistent associations were observed. Notably, a higher intake of low-quality carbohydrates (≥50% of energy intake) was significantly associated with increased LGA risk in the total population (aOR: 4.25; 95% CI: 1.53–11.67; p = 0.005). Conclusions: Higher early pregnancy intake of low-quality carbohydrates was associated with an elevated risk of LGA in the general population. However, CQI itself showed a non-linear and inconsistent relationship with LGA, with moderate, but not high, CQI linked to increased risk, particularly in GDM pregnancies, where associations were lost after adjustment. Both carbohydrate quality and quantity evaluations are essential, particularly in high-risk groups, to inform dietary guidance in pregnancy. Full article
(This article belongs to the Special Issue Recent Advances in Maternal and Fetal Health (2nd Edition))
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13 pages, 1017 KiB  
Systematic Review
Systematic Review of Nutritional Guidelines for the Management of Gestational Diabetes Mellitus: A Global Comparison
by Angelo Sirico, Maria Giovanna Vastarella, Eleonora Ruggiero and Luigi Cobellis
Nutrients 2025, 17(14), 2356; https://doi.org/10.3390/nu17142356 - 18 Jul 2025
Viewed by 586
Abstract
Background: Gestational diabetes mellitus (GDM) affects 7–9% of pregnancies worldwide and is associated with adverse maternal and neonatal outcomes. Nutritional therapy is a key component of GDM management. However, inconsistencies exist across international and national guidelines regarding macronutrient distribution, glycemic targets, and micronutrient [...] Read more.
Background: Gestational diabetes mellitus (GDM) affects 7–9% of pregnancies worldwide and is associated with adverse maternal and neonatal outcomes. Nutritional therapy is a key component of GDM management. However, inconsistencies exist across international and national guidelines regarding macronutrient distribution, glycemic targets, and micronutrient supplementation. This systematic review aims to compare updated nutritional recommendations for GDM across major health organizations and identify areas of consensus, divergence, and evidence gaps. Methods: This systematic review was conducted following PRISMA guidelines and registered in PROSPERO (CRD420251026194). A comprehensive literature search was performed in PubMed, Scopus, and Google Scholar (concluding March 2025), along with manual searches of official websites of professional health organizations (e.g., ADA, WHO, NICE, IDF). Guidelines published within the last 10 years (or the most relevant national guideline if slightly older), available in English or with access to translation, and including explicit nutritional recommendations for GDM were included. Data were extracted on macronutrient composition, glycemic targets, and micronutrient supplementation, with evaluation of the supporting evidence and regional context, incorporating findings from recent key guideline updates. Results: In total, 12 guidelines met the inclusion criteria. While all guidelines emphasized carbohydrate moderation and adequate fiber intake, significant discrepancies were found in carbohydrate quality recommendations (e.g., low-glycemic index focus vs. total carbohydrate restriction), postprandial glucose targets (e.g., 1-h vs. 2-h measurements and varying thresholds like <120 vs. <140 mg/dL), and the use of non-routine micronutrients such as chromium, selenium, and omega-3 fatty acids (generally lacking endorsement). Recent updates from key bodies like ADA, Diabetes Canada, and KDA largely maintain these core stances but show increasing emphasis on dietary patterns and acknowledgement of CGM technology, without resolving key discrepancies. Cultural adaptability and behavioral counselling strategies were minimally addressed across most guidelines. Conclusions: Despite general agreement on the principal recommendations of nutritional management in GDM, substantial variation persists in specific recommendations, even considering recent updates. Consistent, evidence-based, and culturally adaptable guidelines incorporating implementation strategies are needed to optimize care and reduce disparities in GDM management across regions. Full article
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20 pages, 4028 KiB  
Article
Exploring the 3D Printability of Engineered Cementitious Composites with Internal Curing for Resilient Construction in Arid Regions
by Tayyab Zafar, Muhammad Saeed Zafar and Maryam Hojati
Materials 2025, 18(14), 3327; https://doi.org/10.3390/ma18143327 - 15 Jul 2025
Viewed by 367
Abstract
This study investigates the feasibility of pumice-based internal curing based on the 3D printability of engineered cementitious composites (ECCs) for water-scarce environments and arid regions. Natural river sand was partially replaced with the presoaked pumice lightweight aggregates (LWAs) at two different levels, 30% [...] Read more.
This study investigates the feasibility of pumice-based internal curing based on the 3D printability of engineered cementitious composites (ECCs) for water-scarce environments and arid regions. Natural river sand was partially replaced with the presoaked pumice lightweight aggregates (LWAs) at two different levels, 30% and 60% by volume, and 50% of the cement was replaced with slag to enhance sustainability. Furthermore, 2% polyethylene (PE) fibers were used to improve the mechanical characteristics and 1% methylcellulose (MC) was used to increase the rheological stability. Pumice aggregates, presoaked for 24 h, were used as an internal curing agent to assess their effect on the printability. Three ECC mixes, CT-PE2-6-10 (control), P30-PE2-6-10 (30% pumice), and P60-PE2-6-10 (60% pumice), were printed using a 3D gantry printing system. A flow table and rheometer were used to evaluate the flowability and rheological properties. Extrudability was measured in terms of dimensional consistency and the coefficient of variation (CV%) to evaluate printability, whereas buildability was determined in terms of the maximum number of layers stacked before failure. All of the mixes met the extrudability criterion (CV < 5%), with P30-PE2-6-10 demonstrating superior printing quality and buildability, having 16 layers, which was comparable with the control mix that had 18 layers. Full article
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30 pages, 3860 KiB  
Review
OTDR Development Based on Single-Mode Fiber Fault Detection
by Hui Liu, Tong Zhao and Mingjiang Zhang
Sensors 2025, 25(14), 4284; https://doi.org/10.3390/s25144284 - 9 Jul 2025
Viewed by 551
Abstract
With the large-scale application and high-quality development demands of optical fiber cables, higher requirements have been placed on the corresponding measurement technologies. In recent years, optical fiber testing has played a crucial role in evaluating cable performance, as well as in the deployment, [...] Read more.
With the large-scale application and high-quality development demands of optical fiber cables, higher requirements have been placed on the corresponding measurement technologies. In recent years, optical fiber testing has played a crucial role in evaluating cable performance, as well as in the deployment, operation, maintenance, fault repair, and upgrade of optical networks. The Optical Time-Domain Reflectometer (OTDR) is a fiber fault diagnostic tool recommended by standards such as the International Telecommunication Union and the International Electrotechnical Commission. It is used to certify the performance of new fiber links and monitor the status of existing ones, detecting and locating fault events with advantages including simple operation, rapid response, and cost-effectiveness. First, this paper introduces the working principle and system architecture of OTDR, along with a brief discussion of its performance evaluation metrics. Next, a comprehensive review of improved OTDR technologies and systems is provided, categorizing different performance enhancement methods, including the enhanced measurement distance with simple structure and low cost in 2024, and the high spatial resolution measurement of optical fiber reflection events and non-reflection events in 2025. Finally, the development trends and future research directions of OTDR are outlined, aiming to achieve the development of low-cost, high-performance OTDR systems. Full article
(This article belongs to the Special Issue Fault Diagnosis Based on Sensing and Control Systems)
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15 pages, 2395 KiB  
Article
The Characterization of a Chitosan Coating Enriched with Bamboo-Leaf Flavonoids and Its Effect on Postharvest Preservation of Three Horticultural Products
by Haoran Wu, Feng Tang and Xi Yao
Foods 2025, 14(13), 2364; https://doi.org/10.3390/foods14132364 - 3 Jul 2025
Viewed by 356
Abstract
Chitosan coatings have been demonstrated to be a highly effective and safe approach to extending the shelf life of food. This study, for the first time, evaluates the effectiveness of bamboo-leaf flavonoids (BLFs) added to a chitosan coating to delay the spoilage of [...] Read more.
Chitosan coatings have been demonstrated to be a highly effective and safe approach to extending the shelf life of food. This study, for the first time, evaluates the effectiveness of bamboo-leaf flavonoids (BLFs) added to a chitosan coating to delay the spoilage of strawberries, blueberries, and bamboo shoots. The addition of BLFs improved the tensile strength of the coatings. Chitosan coating incorporated with 0.1% BLFs had the highest tensile strength (36.38 ± 2.69 MPa). BLFs conferred antioxidant properties to chitosan coatings as determined by DPPH radical scavenging activity. Key quality parameters were measured over the storage period of strawberries, blueberries, and bamboo shoots. The coating significantly affected the impact of storage time on some variables. Chitosan/BLF coatings were particularly effective in limiting changes over time in weight loss, spoilage percentage, and vitamin C content (strawberries and blueberries), as well as crude fiber content (bamboo shoots), although their effect on titratable acid, soluble solids, and soluble protein content was less pronounced. The chitosan/BLFs composite coating demonstrated superior efficacy over pure chitosan in delaying spoilage. In conclusion, the chitosan/BLF coating could be useful for maintaining the quality of strawberries, blueberries, and bamboo shoots. Full article
(This article belongs to the Section Food Packaging and Preservation)
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16 pages, 317 KiB  
Article
Defining Multi-Trait Breeding Objectives and Selection Indexes to Develop More Efficient Breeding Programs for Superfine Wool Sheep
by Tingting Guo, Wenhui Li, Chao Yuan, Xijun Wang, Jianbin Liu and Bin Liang
Animals 2025, 15(13), 1873; https://doi.org/10.3390/ani15131873 - 24 Jun 2025
Viewed by 384
Abstract
This study aimed to develop an optimized breeding program for the Alpine Merino sheep superfine strain by defining breeding objectives and establishing a multi-trait selection index. Using phenotypic and genetic (co)variance components of wool and growth traits, we identified six key breeding objectives: [...] Read more.
This study aimed to develop an optimized breeding program for the Alpine Merino sheep superfine strain by defining breeding objectives and establishing a multi-trait selection index. Using phenotypic and genetic (co)variance components of wool and growth traits, we identified six key breeding objectives: average fiber diameter (AFD), clean fleece weight (CFW), staple strength (SS), staple length (YSL), yearling weight (YWT), and weaning weight (WWT), with economic weights of 48, 48.5, 2, 12, 2.85, and 25, respectively. Through eco-bio modeling comparing three index sets with different trait combinations and information sources, we determined the optimal index comprising the AFD, CFW, fiber diameter coefficient of variation (FDcv), YSL, YWT, and WWT using data from individual phenotypes and 10 half-sibs. Recommended ram and ewe utilization periods were 3 and 5 years, respectively. Projected 10-year genetic gains showed improvements of −2 μm (AFD), 0.57 kg (CFW), 20 N/ktex (SS), 0.6 cm (YSL), 4.73 kg (YWT), and 0.38 kg (WWT). The developed program enhances both superfine wool characteristics and overall wool quality while improving the selection accuracy. Additionally, we propose alternative indices for varying measurement contexts and discuss strategies to accelerate genetic gains, including optimizing ewe reproduction rates and ram selection precision, and incorporating progeny information. Full article
(This article belongs to the Section Animal Genetics and Genomics)
19 pages, 2218 KiB  
Article
Phenotypic Validation of the Cotton Fiber Length QTL, qFL-Chr.25, and Its Impact on AFIS Fiber Quality
by Samantha J. Wan, Sameer Khanal, Nino Brown, Pawan Kumar, Dalton M. West, Edward Lubbers, Neha Kothari, Donald Jones, Lori L. Hinze, Joshua A. Udall, William C. Bridges, Christopher Delhom, Andrew H. Paterson and Peng W. Chee
Plants 2025, 14(13), 1937; https://doi.org/10.3390/plants14131937 - 24 Jun 2025
Viewed by 488
Abstract
Advances in spinning technology have increased the demand for upland cotton (Gossypium hirsutum L.) cultivars with superior fiber quality. However, progress in breeding for traits such as fiber length is constrained by limited phenotypic and genetic diversity within upland cotton. Introgression from [...] Read more.
Advances in spinning technology have increased the demand for upland cotton (Gossypium hirsutum L.) cultivars with superior fiber quality. However, progress in breeding for traits such as fiber length is constrained by limited phenotypic and genetic diversity within upland cotton. Introgression from Gossypium barbadense, a closely related species known for its superior fiber traits, offers a promising strategy. Sealand 883 is an obsolete upland germplasm developed through G. barbadense introgression and is known for its long and fine fibers. Previous studies have identified a fiber length quantitative trait locus (QTL) on Chromosome 25, designated qFL-Chr.25, in Sealand 883, conferred by an allele introgressed from G. barbadense. This study evaluated the effect of qFL-Chr.25 in near-isogenic introgression lines (NIILs) using Advanced Fiber Information System (AFIS) measurements. Across four genetic backgrounds, NIILs carrying qFL-Chr.25 consistently exhibited longer fibers, as reflected in multiple length parameters, including UHML, L(n), L(w), UQL(w), and L5%. Newly developed TaqMan SNP diagnostic markers flanking the QTL enable automated, reproducible, and scalable screening of large populations typical in commercial breeding programs. These markers will facilitate the incorporation of qFL-Chr.25 into commercial breeding pipelines, accelerating fiber quality improvement and enhancing the competitiveness of cotton against synthetic fibers. Full article
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23 pages, 2366 KiB  
Article
Whole-Cell Fiber-Optic Biosensor for Real-Time, On-Site Sediment and Water Toxicity Assessment: Applications at Contaminated Sites Across Israel
by Gal Carmeli, Abraham Abbey Paul, Kathelina Kristollari, Evgeni Eltzov, Albert Batushansky and Robert S. Marks
Biosensors 2025, 15(7), 404; https://doi.org/10.3390/bios15070404 - 22 Jun 2025
Viewed by 1399
Abstract
Sediments are key players in the optimum functioning of ecosystems; however, they also represent the largest known repository of harmful contaminants. The vast variety of these sediment-associated contaminants may exert harmful effects on marine communities and can impair ecosystem functioning. Whole-cell biosensors are [...] Read more.
Sediments are key players in the optimum functioning of ecosystems; however, they also represent the largest known repository of harmful contaminants. The vast variety of these sediment-associated contaminants may exert harmful effects on marine communities and can impair ecosystem functioning. Whole-cell biosensors are a rapid and biologically relevant tool for assessing environmental toxicity. Therefore, in this study, we developed a bioassay-based toxicity measurement system using genetically modified bacteria to create a whole-cell optical biosensor. Briefly, reporter bacteria were integrated and immobilized using a calcium alginate matrix on fiber-optic tips connected to a photon counter placed inside a light-proof, portable case. The calcium alginate matrix acts as a semi-permeable membrane that protects the reporter-encapsulated optical fiber tips and allows the inward passage of toxicant(s) to induce a dose-dependent response in the bioreporter. The samples were tested by directly submerging the fiber tip with immobilized bacteria into vials containing either water or suspended sediment samples, and the subsequent bioluminescent responses were acquired. In addition to bioavailable sediment toxicity assessments, conventional chemical methods, such as liquid chromatography–mass spectroscopy (LC-MS) and inductively coupled plasma optical emission spectroscopy (ICP-OES), were used for comprehensive evaluation. The results demonstrated the efficacy of the biosensor in detecting various toxicity levels corresponding to identified contaminants, highlighting its potential integration into environmental monitoring frameworks for enhanced sediment and water quality assessments. Despite its utility, this study notes the system’s operational challenges in field conditions, recommending future enhancements for improved portability and usability in remote locations. Full article
(This article belongs to the Special Issue Optical Biosensors for Environmental Monitoring)
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18 pages, 7866 KiB  
Article
Apocynin Mitigates Diabetic Muscle Atrophy by Lowering Muscle Triglycerides and Oxidative Stress
by Sarai Sánchez-Duarte, Elizabeth Sánchez-Duarte, Luis A. Sánchez-Briones, Esperanza Meléndez-Herrera, Ma. Antonia Herrera-Vargas, Sergio Márquez-Gamiño, Karla S. Vera-Delgado and Rocío Montoya-Pérez
Int. J. Mol. Sci. 2025, 26(12), 5636; https://doi.org/10.3390/ijms26125636 - 12 Jun 2025
Viewed by 593
Abstract
Diabetic muscular atrophy is a complication of diabetes mellitus that can decrease quality of life. Its complex mechanisms include alterations in proteolytic pathways, oxidative stress, and intracellular lipid accumulation. NADPH oxidase enzymes (NOX) play a key role in the production of ROS, contributing [...] Read more.
Diabetic muscular atrophy is a complication of diabetes mellitus that can decrease quality of life. Its complex mechanisms include alterations in proteolytic pathways, oxidative stress, and intracellular lipid accumulation. NADPH oxidase enzymes (NOX) play a key role in the production of ROS, contributing to oxidative damage and insulin resistance. Apocynin, a NOX inhibitor, has antioxidant and anti-inflammatory effects, suggesting its therapeutic potential in various diabetic complications. This study evaluated the impact of apocynin on the mechanisms of muscle atrophy in slow- and fast-twitch muscles of diabetic rats. Diabetes was induced in male Wistar rats by intraperitoneal injection of a single dose of streptozotocin (60 mg/kg). Apocynin treatment (3 mg/kg/day) was administered for 8 weeks. Fasting blood glucose levels, lipid profile, and weight gain were measured. Both slow-twitch (soleus) and fast-twitch (extensor digitorum longus, EDL) skeletal muscles were weighed and used to assess triglycerides (TG) content, histological analysis, lipid peroxidation levels, and gene expression evaluated by qRT-PCR. Apocynin reduced blood glucose levels, improved body weight, and exhibited hypolipidemic effects. It significantly increased muscle weight in EDL and soleus, especially in EDL muscle, lowering triglycerides, lipid peroxidation, and increasing fiber size. Additionally, it decreased mRNA expression levels of MuRF-1, atrogin-1, myostatin and p47phox mRNA and upregulated PGC-1α and follistatin mRNA. Apocynin exerted a myoprotective effect by mitigating muscle atrophy in diabetic rats. Its effects were differentially mediated on TG accumulation and muscle fiber size, reducing oxidative stress, atrogene expression, and positively regulating PGC-1α. Full article
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25 pages, 2610 KiB  
Article
Growth Performance and Nutritional Content of Tropical House Cricket (Gryllodes sigillatus (Walker, 1969)) Reared on Diets Formulated from Weeds and Agro By-Products
by Henlay J. O. Magara, Sylvain Hugel and Brian L. Fisher
Insects 2025, 16(6), 600; https://doi.org/10.3390/insects16060600 - 6 Jun 2025
Viewed by 831
Abstract
The tropical house cricket (Gryllodes sigillatus) can convert organic diets formulated from weeds and agro by-products into high-quality biomass. This study assessed the potential of diets developed from weeds and agro by-products as a feed source for G. sigillatus. We [...] Read more.
The tropical house cricket (Gryllodes sigillatus) can convert organic diets formulated from weeds and agro by-products into high-quality biomass. This study assessed the potential of diets developed from weeds and agro by-products as a feed source for G. sigillatus. We compared the development and nutritional value of crickets fed these alternative diets with control crickets fed chicken feed. Ten different diets with varying protein contents were used, including chicken feed (Control) with a protein content of 215 g/Kg dry matter (DM) basis), Cassava–Sugar Diet (250 g/Kg DM protein) Desmodium–Bran Diet (245 g/Kg DM protein), Morning Glory–Bean Diet (240 g/Kg DM protein), Morning Glory–Cassava Diet (235 g/Kg DM protein), Morning Glory–Cowpea Diet (225 g/Kg DM protein), Mixed Weed–Bran Diet (Optimal) (215 g/Kg DM protein) Cassava–Gallant Soldier Diet (200 g/Kg DM protein), Wheat–Bran Diet (145 g/Kg DM protein), and Maize–Cassava Diet (135 g/Kg DM protein). The weight and length of the crickets were measured for 9 weeks from day 1 after hatching to day 56. Then, the crickets were harvested and analyzed for dry matter, crude protein, fat, ash, fiber, minerals, and fatty acid composition. Cricket developmental time, survival rate, weight and length, yield, proximate components, and mineral and fatty acids differed depending on the diet provided. The Mixed Weed–Bran Diet (Optimal) resulted in the crickets developing faster (48.8 days), with a higher survival rate (88.1%), greater adult length (19.2 cm) and weight (0.44 g), and a nutrition content richer in minerals and unsaturated fatty acids when compared to other treatments. Oleic, linoleic, and palmitic acids were the major fatty acids. The highest protein content (64.4 g/100 g) was observed in the Mixed Weed–Bran Diet (Optimal) and Morning Glory–Cassava Diet treatments, while the Maize–Cassava Diet treatment crickets possessed the highest quantities of fats (19.1 g/100 g) and ash (15.4 g/100 g). The fatty acid profile of G. sigillatus revealed the cricket to have high unsaturated fatty acids except in crickets fed Morning Glory–Cowpea Diet and Wheat–Bran Diet. Generally, G. sigillatus grew best and had the most nutritious body composition on the Mixed Weed–Bran Diet (Optimal). The findings indicate that diets developed from weeds and agro by-products have great potential to be used as an alternative feed source for crickets and are capable of replacing expensive chicken feed, enhancing the circular farming potential of insect farming. Full article
(This article belongs to the Special Issue Insects as the Nutrition Source in Animal Feed)
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19 pages, 930 KiB  
Article
Botulinum Toxin A for Elbow Flexor Spasticity: A Non-Randomized Observational Study of Muscle-Specific Injection Strategies
by Miruna Ioana Săndulescu, Delia Cinteză, Daniela Poenaru, Claudia-Gabriela Potcovaru, Horia Păunescu and Oana Andreia Coman
J. Clin. Med. 2025, 14(11), 3864; https://doi.org/10.3390/jcm14113864 - 30 May 2025
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Abstract
Introduction: Elbow flexor spasticity is a common and debilitating consequence of stroke, significantly impacting patients’ quality of life. Botulinum toxin A (BoNT-A) injections have emerged as an effective treatment, but the optimal muscle selection strategy remains unclear. This study investigates the impact of [...] Read more.
Introduction: Elbow flexor spasticity is a common and debilitating consequence of stroke, significantly impacting patients’ quality of life. Botulinum toxin A (BoNT-A) injections have emerged as an effective treatment, but the optimal muscle selection strategy remains unclear. This study investigates the impact of different BoNT-A injection strategies targeting specific elbow flexor muscles in post-stroke patients. Materials and Methods: A non-randomized observational study was conducted on 52 participants with upper limb spasticity (pattern IV) following a stroke. Participants were divided into three groups based on the elbow flexor muscles injected with BoNT-A: biceps brachii (n = 15), brachialis (n = 9), and brachialis plus brachioradialis (n = 28). Assessments included spasticity angle, paresis angle, and active supination range of motion (ROM) measured using the Tardieu Scale and goniometry at baseline and at 4-week follow-up. Non-parametric statistical analyses were employed to compare outcomes between groups. Results: While all groups showed a general trend of decreased spasticity and improved motor control, analysis revealed statistically significant differences across the groups at baseline. The brachialis plus brachioradialis group demonstrated the most substantial improvement in paresis angle and active supination ROM. Notably, this group also exhibited greater capacity for the improvement of the paresis angle. The biceps brachii group showed comparable improvements in the paresis angle and the greatest effect on improving passive extension at slow velocity with increasing stroke onset but required higher pronator teres BoNT-A doses overall. Discussion: These findings suggest that individualized muscle selection strategies are crucial in BoNT-A treatment for elbow flexor spasticity. The superior outcomes observed in the brachialis plus brachioradialis group may be attributed to the synergistic action of these muscles in elbow flexion and forearm positioning. The higher pronator teres BoNT-A doses required in the biceps brachii group may reflect compensatory mechanisms or differences in muscle fiber recruitment patterns. Conclusions: Combining brachialis and brachioradialis muscles in BoNT-A injections appears to offer superior benefits for supination and motor control in post-stroke patients with elbow flexor spasticity, particularly those with significant elbow flexion and pronation. Full article
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