Search Results (6,399)

Antimicrobial resistance (AMR) is one of the most significant threats to healthcare systems, particularly in low- and middle-income nations where infection prevention and control, antimicrobial stewardship, and laboratory surveillance might not be optimal. Acinetobacter baumannii is a high-risk nosocomial pathogen that has a strong capacity to develop extreme resistance phenotypes. Still, the degree to which extensively drug-resistant (XDR) and pandrug-resistant (PDR) phenotypes reflect the cumulative impact of antimicrobial pressure at unit and system levels in Iraqi hospitals is not fully described. This was a cross-sectional surveillance study that was a laboratory-based investigation done in public hospitals in the Governorate of Kirkuk between January 2024 and January 2025. The BD Phoenix system identified 80 non-duplicate A. baumannii isolates that were obtained in high-risk hospital units. The interpretation of antimicrobial susceptibility testing was done according to CLSI guidelines. Internationally recognized definitions were adjusted to local therapeutic availability to classify isolates as XDR or PDR. Unadjusted odds ratios and Fisher’s exact test were used to assess the associations between the PDR phenotype and the chosen clinical or unit-level variables. Among the 80 isolates, 60 (75%) were XDR and 20 (25%) were PDR. Burn units and wound-related infections were disproportionately represented by PDR isolates. There were significant associations between the PDR phenotype and burn unit admission, wound infection, exposure to invasive devices, long hospitalization (greater than 14 days), and previous exposure to broad-spectrum antibiotics. ICU admission and respiratory infection were not significantly related. Cefepime had in vitro activity only in a subset of XDR isolates. Extreme resistance phenotypes can be used as convenient sentinel measures of cumulative antimicrobial pressure and system-level stress in resource-limited environments. There is an urgent need to strengthen infection prevention and control, antimicrobial stewardship, and laboratory surveillance to preserve the remaining therapeutic options. Full article

Agricultural waste streams represent an underutilized source of bioactive compounds with potential to enhance crop resilience under climate stress. We previously showed that volatile compounds (VCs) emitted from waste shiitake fungi beds (WSFBs) promote early rice seedling growth under controlled conditions. Here, we evaluated whether these early-stage effects persist after transplanting and translate into agronomic benefits under field conditions, including the record high temperatures (HTs) of the 2023 growing season in Niigata, Japan. Seedlings of two japonica cultivars, Nipponbare and Koshihikari, were exposed to WSFBs-derived VCs using a non-contact system and subsequently grown in paddy fields across two seasons (2023–2024). WSFBs-VCs-treated (+VCs) plants exhibited enhanced seedling vigor, increased tiller and panicle numbers, higher grain yield per plant, greater 1000-grain weight, and reduced grain chalkiness. Gas exchange measurements at the reproductive stage during the 2023 record HT showed that +VCs plants maintained higher net photosynthetic rate, stomatal conductance, intercellular CO₂ concentration, and transpiration rate, while intrinsic water-use efficiency showed a modest decline consistent with transpirational cooling. Controlled-environment assays revealed enhanced physiological stability supported by upregulation of cytokinin and stress-responsive genes under acute heat stress. Together, these results demonstrate that short-term exposure to WSFBs-derived VCs enhances rice performance under field conditions, including during extreme heat, and highlight their potential as low-cost, waste-derived biostimulants that support sustainable, circular, and climate-resilient rice production. Full article

Understanding long-term hydroclimatic variability in arid and semi-arid regions is essential for sustainable water resource management in the context of accelerating climate change. This study examines historical trends (1950–2024) and data-driven extrapolations to 2040 for precipitation and temperature across 30 secondary river basins in Iran using ERA5 reanalysis dataset and the Light Gradient Boosting Machine (LightGBM) model. Results reveal pronounced spatial heterogeneity in precipitation, with more than two-thirds of basins showing median values of 0 mm, reflecting extreme rainfall intermittency. Long-term analysis indicates significant precipitation increases in northern basins, whereas decadal trends show widespread drying since the early 2000s, particularly in eastern regions (30–60 mm per decade). Mean, maximum, and minimum temperatures exhibit significant upward trends (0.015–0.045 °C yr⁻¹), with stronger warming in northern and northwestern basins; however, minimum temperatures increased faster than maximum temperatures, reducing the diurnal temperature range and indicating a shift in regional thermal dynamics. Maximum temperature is negatively correlated with precipitation (R ≈ −0.27 to −0.34), suggesting enhanced evapotranspiration under warming conditions. LightGBM extrapolations to 2040 indicate continued warming (1–3 °C) and precipitation declines across more than 80% of Iran, underscoring intensifying hydroclimatic stress and increasing challenges for water resource management in dryland environments. Full article

Urban canyons, integral components of the built environment, significantly influence microclimatic conditions and thermal comfort. This review investigates their combined effects with green infrastructure on thermal comfort, offering a comprehensive framework for supporting urban design and greening strategies. The review is based on a structured literature analysis of peer-reviewed studies retrieved from major scientific databases (Scopus and Web of Science), following defined selection and screening criteria. Urban canyon orientation determines solar exposure and its interaction with prevailing wind patterns, affecting ventilation and heat dissipation. The urban canyon aspect ratio influences shading and airflow regulation, while their sky view factor moderates radiative cooling and daylight availability. Urban greening—encompassing street trees, green roofs, and vertical green walls—complements urban geometry by reducing air temperatures, enhancing evapotranspiration, and modifying local wind dynamics. Tree shading can reduce the physiological equivalent temperature in urban canyons, mitigating extreme heat stress. Key vegetative parameters, such as leaf area index and canopy density, are critical for quantifying cooling contributions. Key findings underscore the role of higher aspect ratios in enhancing shading and ventilation while they emphasize the critical influence of street orientation and sky view factor on microclimatic regulation. Vegetation emerges as a vital component, with tree shading contributing substantially to cooling effects and reducing physiological equivalent temperature. The beneficial synergistic interaction between urban geometry and vegetation optimizes thermal comfort. Tailored strategies based on urban canyon typologies balance urban development with environmental sustainability. The proposed framework provides actionable strategies for designing resilient and thermally optimized urban spaces, promoting climate-adaptive urban planning by addressing the dual challenges of the urban heat island and thermal discomfort in cities. Full article

Background/Objectives: Left ventricular free wall rupture is a rare but catastrophic complication of acute myocardial infarction with extremely high mortality. Deaths occurring in water environments present unique forensic challenges requiring systematic evaluation of drowning, intoxication, trauma, and natural disease. This case report describes a fatal left ventricular free wall rupture occurring shortly after successful percutaneous coronary intervention (PCI), emphasizing the medicolegal differential diagnosis and the importance of comprehensive postmortem evaluation. Results: A 58-year-old man with non-ST-elevation myocardial infarction underwent successful PCI with three drug-eluting stents and was discharged home. Six hours later, he developed severe back pain and was found unresponsive in a bathtub. Autopsy demonstrated a 2.6 cm transmural rupture of the anterolateral left ventricular free wall with 150 mL of hemopericardium. Postmortem computed tomography (PMCT), performed as part of routine forensic evaluation, had identified hemopericardium prior to autopsy. Histology showed coagulative necrosis with neutrophilic infiltration. The rupture site was remote from stented vessels with no procedural injury. Toxicology revealed therapeutic medication levels. Pulmonary and scene findings did not support drowning as a cause of death. Conclusions: Ventricular free wall rupture remains a relevant cause of sudden death following myocardial infarction despite successful revascularization. Comprehensive forensic evaluation integrating scene investigation, macroscopic autopsy findings, histopathology, and toxicology is essential to distinguish natural disease progression from accidental or iatrogenic causes in deaths occurring in water environments. This case highlights that ventricular free wall rupture can occur shortly after apparently successful PCI and underscores the importance of comprehensive forensic evaluation in water-associated deaths. Full article

Coal gangue (CG) and iron tailings (ITs) are major industrial solid wastes, and their high-value reuse is crucial for sustainable construction materials. This study explores the feasibility of fabricating sintered porous bricks using CG and ITs as primary constituents, with shale as an auxiliary component. To evaluate durability in cold regions, laboratory freeze–thaw (F-T) cycling experiments were conducted. A degradation assessment framework based on the Wiener stochastic process was developed to predict frost-resistance service life by integrating experimental data with regional climatic conditions. Results show that the fabricated bricks exhibit satisfactory initial properties, with a compressive strength of 10.6 MPa and water absorption of 13.3%. With increasing F-T cycles, compressive strength decreases significantly, accompanied by increased mass loss and water absorption. Stress–strain analysis reveals progressive stiffness reduction and a transition from brittle to ductile failure. Microstructural observations confirm degradation of the glassy phase, pore expansion, and enhanced interconnectivity. The Wiener process-based model effectively describes the stochastic accumulation of F-T damage. By establishing equivalence between laboratory and natural F-T cycles, the long-term service life of coal gangue–iron tailing sintered porous bricks (CG-IT SPBs) in cold regions is theoretically evaluated. This work provides an integrated understanding of F-T damage behavior and establishes a scientific foundation for durability-oriented design and application of such bricks in extremely cold environments. Full article

Puerto Rico has experienced increasingly frequent and intense extreme heat conditions in recent years, with the 2023–2024 warm seasons standing out for prolonged periods of dangerously high heat index values and widespread spatial exposure. These conditions are particularly concerning in tropical island environments, where high humidity limits physiological cooling and amplifies heat-related health risks. The main objective of this study is to identify and characterize extreme heat zones and events across Puerto Rico using NOAA-modeled heat index (apparent temperature) data, as well as to examine their spatial and temporal variability during the 2021–2024 period. Hourly modeled apparent temperature data between 2 and 4 pm, representing the warmest time of day, were analyzed for each day from June through October. Mean maximum and maximum heat index surfaces were generated for each month and warm season, and extreme heat zones were identified using the 103 °F (39.4 °C) danger threshold. Results show a persistent concentration of extreme heat in low-elevation coastal regions, particularly across the northern coastal plains from San Juan to Hatillo, with floodplain areas in Arecibo and Manatí exhibiting the highest and most consistent exposure. August was identified as the month with the highest mean maximum heat index across all study years, followed by September. The warm seasons of 2023 and 2024 exhibited the highest magnitudes and spatial extents of extreme heat, with some regions experiencing apparent temperatures exceeding 110 °F and up to 141 extreme heat days during peak afternoon hours. The findings indicate a transition from localized heat hotspots to widespread and sustained extreme heat exposure across Puerto Rico’s coastal regions. This study provides an island-scale assessment of extreme heat patterns with direct implications for public health, infrastructure planning, and heat-risk management in a warming tropical climate. Full article

The nonlinear dynamic response of aerospace thin-walled structures in a post-buckling state under thermo-acoustic loads is critical for their design. This study investigates this phenomenon through integrated experimental and numerical approaches. Acoustic tests on thermally stressed flat plates yielded results in close agreement with finite element and reduced-order modal (FEM/ROM) simulations, with first-order frequency deviations within ±2 Hz and strain values of the same order of magnitude (10.7 µε vs. 9.5 µε at 50 °C). A key observation is the non-monotonic variation in the thermal modal frequency, which initially decreases then increases with the buckling coefficient, while dynamic strain data further validate the computational model. Comparative analysis of three Haynes 188 alloy geometries—flat plates, cylindrical shells, and spherical shells—reveals distinct behaviors rooted in their critical buckling temperatures (68.46 °C, 151.20 °C, and 698.28 °C, respectively): flat plates exhibit softening–hardening transitions with a frequency range of 491–624 Hz; cylindrical shells show irregular responses with a dramatic frequency drop from 1120 Hz to 360 Hz; and spherical shells maintain the highest stability and frequency range (1913–2109 Hz), governed by the buckling coefficient’s linear effect. Time-domain and probability density function (PDF) analyses elucidate the snap-through phenomena and the modulating roles of the buckling coefficient and sound pressure level (SPL). These findings underscore that geometric configuration and inherent stiffness are critical to post-buckling performance, providing a theoretical basis for designing aerospace components in extreme environments. Full article

In the context of escalating global warming and the urban heat island effects, recurrent extreme heat events will increase the exposure risk of cyclists, which will have a detrimental effect on both health and the sustainability of active mobility. Nevertheless, this risk has not been given sufficient attention. To accurately quantify the levels of solar radiation exposure experienced by cyclists in high-temperature conditions and the impact of the built environment on these levels, this study focuses on central Shanghai as a case study. The integration of Mobike trajectories, street view imagery, and solar radiation data sets enabled the quantification of trip-level cumulative radiation exposure and per-minute exposure levels. Subsequently, the XGBoost–SHAP interpretability framework was employed to decipher the mechanisms of the built environment. The following key findings have been identified: (1) Spatiotemporally, the radiation exposure level of cyclists exhibited an inverted U-shaped pattern, peaking at midday (10:00–15:00), with per-minute values of 862–943 W/m². This intensity significantly exceeded that observed during the morning (407 W/m²) and evening (253 W/m²). (2) It was determined that geometric factors dominated the radiative exposure level. The shading index demonstrated a critical influence (57% contribution), with exposure reduction intensifying beyond 0.41 yet exhibiting diminishing marginal effects after 0.6. The sky view factor and building height elevated exposure risk by amplifying direct solar radiation. (3) Socioeconomic factors had divergent effects on the radiation exposure level of cyclists: commercial/business densities reduced exposure through continuous building shade, whereas transportation facility density increased exposure due to low-shaded layouts. Consequently, this study proposes “shaded corridors” as a core mitigation strategy, establishing a tripartite intervention framework (spatial-facility-governance) for radiation exposure reduction. The present study provides scientific foundations for the targeted enhancement of heat resilience in active mobility. Full article

The Mediterranean Basin faces increasing risks from extreme weather events, particularly heat stress, which severely threatens the productivity of sensitive crops, like processing tomato (Solanum lycopersicum L.). This study evaluated the agronomic, physiological, quality, and economic performance of using Mater-Bi^®-based biodegradable mulch films—varying in color (black and White/Black) and thickness (12 µm and 15 µm)—in two distinct Southern Italian pedoclimatic sites: Sicily and Campania. The aim was to define site-specific optimization strategies by comparing three biodegradable mulch film treatments, 12 µm (BDM12), 15 µm (BDM15), and Black/White (BDBW), against bare soil (BS). The results confirmed that biodegradable mulching enhances plant physiological status, such as chlorophyll and nitrogen balance index (NBI), and marketable yield compared to BS. The effectiveness of the films depended significantly on the environment. In Sicily, the BDBW (White/Black) film provided the maximum marketable yield (804.7 q ha⁻¹), confirming its crucial role in mitigating high soil temperatures through radiation reflection. Conversely, in the more favorable Campanian environment, the thicker black film (BDN15) achieved the highest yield (867.3 q ha⁻¹), indicating that microclimate stability is prioritized over heat mitigation under optimal conditions. Quality analysis showed high variability; while the Sicilian site generally favored color and antioxidant capacity, total soluble solids (°Brix) exhibited a trade-off. BDBW achieved the highest °Brix (6.1) in Sicily, while BS yielded the highest (6.03) in Campania, suggesting that slight water stress can concentrate sugars at the expense of total yield. The economic analysis demonstrated that the °Brix increase achieved with biodegradable films provided a net additional economic return superior to BS in both sites (up to +52.92% with BDBW). These findings suggest that the adoption of biodegradable mulching represents a key strategy for the sustainable intensification of processing tomato. Future cultivation strategies must mandatorily integrate the personalized selection of film color and thickness as a key element to synergistically maximize yield, quality, and economic return, tailored to the specific pedoclimatic conditions of each production site. Full article

Geological hazards induced by large-scale and high-intensity mining activities worldwide are primary drivers of regional ecological degradation and pose significant threats to human safety and property. To construct efficient monitoring systems and enhance early warning capabilities, it is essential to clarify the formation mechanisms of various hazards and the suitability of corresponding technologies. Focusing on four typical geological hazards prevalent in mining areas (surface subsidence, ground fissures, landslides, collapses, and sinkholes), this paper characterizes their specific features and monitoring requirements. It systematically analyzes the physical principles, accuracy levels, and technical advantages and limitations of ground-based, aerial, and spaceborne monitoring, as well as multi-source remote sensing data fusion and emerging technologies (e.g., distributed optical fiber, light detection and range, microseismical monitoring, and deep learning). Utilizing case studies from an open-pit coal mine in Turkey and a loess gully mining area in China, the paper evaluates the effectiveness of methods like multi-temporal InSAR and UAV photogrammetry in identifying the evolution of these hazards. The findings indicate that the technological framework for mining area monitoring is transitioning from single-method approaches to integrated systems. However, given the complex mining environment, several bottleneck challenges remain, including single data dimensions, the limited environmental adaptability of aerospace remote sensing, insufficient stability of deep monitoring equipment, and weak anti-interference capabilities under extreme operating conditions. Consequently, this paper proposes that future innovations in geological hazard monitoring in mining areas will focus on multi-platform hierarchical collaboration, the development of multi-parameter fusion early warning criteria, and the construction of digital and visual platforms. Constructing a comprehensive monitoring system characterized by multi-scale collaboration and dynamic prediction capabilities is vital for improving safety standards in mining areas and achieving coordinated development between resource exploitation and environmental protection. The findings provide a theoretical foundation for the precise prevention and control of mining hazards, as well as for land ecological restoration. Full article

Rare earth hafnates (RE₂Hf₂O₇; RE = La, Gd, Nd, Eu, etc.) with low thermal conductivity and excellent high-temperature stability are indispensable key materials in extreme environments and high-tech fields. In this work, a dense molten salt method (DMS) was developed for mass preparation of hafnate powders including La₂Hf₂O₇, Nd₂Hf₂O₇, Gd₂Hf₂O₇, Eu₂Hf₂O₇, and even (La_0.2Nd_0.2Sm_0.2Eu_0.2Gd_0.2)₂Hf₂O₇, which only allowed the trace salt volatilization, while the internal salt “micro-pools” significantly promoted the in-situ formation of target products at relatively lower temperatures. Using La₂Hf₂O₇ as an example, it could be successfully prepared at 1100 °C with 1:1 mass ratio of salt to reactant, both of which are much lower than those of traditional “powdery” molten salt method. Furthermore, only ~6 wt.% of salt loss was detected in current dense route, while it was as high as ~80 wt.% in the traditional one. A large-scale synthesis of RE₂Hf₂O₇ powder by DMS may be achievable by stacking these dense blocks in a tunnel kiln, suggesting its potential applicability and scalability toward industrial production. Full article

Compressed air systems (CASs) represent a significant portion of energy consumption in large-scale built environments and manufacturing facilities, suffering from both micro-level physical pipeline leaks and macro-level operational inefficiencies. This paper proposes a unified, dual-action artificial intelligence framework aimed at advancing building decarbonization by systematically integrating acoustic-vision leak quantification with schedule-aware machine learning. Specifically, the framework targets pneumatic pipe connection leaks, fitting leaks, and joint degradation faults within compressed air distribution networks, which are the primary sources of micro-level volumetric energy losses in industrial building systems. First, a probabilistic multimodal fusion algorithm (MPSF) using an ultrasonic camera is developed to detect and geometrically quantify physical leaks, successfully translating pixel areas into physical facility energy loss metrics (estimating 11.0 kW of wasted power from detected severe leaks). Second, to optimize the compressor’s supply matching the actual facility demand without risking data leakage from internal flow sensors, an eXtreme Gradient Boosting (XGBoost) model is proposed. By utilizing only external building environmental conditions and the real-time operational schedules of 13 distinct zones, the model achieves highly accurate dynamic power prediction (R² = 0.9698). Finally, comprehensive simulations based on real-world digital monitoring data from a facility-scale built environment demonstrate that only the concurrent application of both modules ensures stable end-point pressure. The integrated framework achieves a substantial system-wide building energy reduction of over 20% to 40% compared to baseline constant-pressure operations, yielding an estimated annual reduction of 116 tons of CO₂ emissions, thereby providing a direct pathway toward carbon-neutral building operations. Full article

Voice disorders severely limit verbal communication, creating a need for intuitive assistive technologies. To meet this need, we present epidermal strain sensors that capture strain signals during silent speech and hand gesture. A thin electrospun nanofiber layer integrated onto commercial polyurethane films guides uniform, controlled microcrack formation in screen-printed carbon conductive paths, achieving a gauge factor up to 243 over 0–40% strain. Signals from the seven-channel strain sensor array are recognized by a hybrid neural network that combines convolutional and Transformer architectures, reaching over 98% accuracy. The recognized outputs are rendered in virtual reality (VR), enabling intuitive, real-time communication. Moreover, the approach simplifies fabrication by enabling crack-based strain sensing with only a thin electrospun surface layer on commercial polyurethane films, eliminating the need for thick freestanding electrospun substrates. This cost-effective approach addresses limitations of conventional electrospun substrates by minimizing the thickness of the electrospun layer, thereby shortening the electrospinning time. Overall, the work demonstrates a method for translating natural non-verbal expressions into speech and text in VR, with promising applications in healthcare and assistive communication. Full article

Sandstone-hosted uranium deposits in the western Qaidam Basin are spatially associated with hydrocarbon-bearing structures, yet the specific roles of different sulfur sources in uranium mineralization remain poorly constrained. This study aims to distinguish the contributions of bacterial sulfate reduction and hydrocarbon-associated sulfate reduction to uranium precipitation by integrating detailed petrography, in situ trace element analyses, and sulfur isotope measurements of chalcopyrite from the Yuejin Ⅱ deposit. Chalcopyrite is restricted to high-grade uranium ores and occurs intergrown with uranium minerals, pyrite, baryte, and carbonate cements. Trace element patterns indicate that oxidizing brines acted as the main transport medium for both uranium and copper, as evidenced by positive correlations between U and brine-related elements (Ba, Sr, Na, K). Positive U-Th correlations with relatively constant Th/U ratios (0.027–0.225) reflect a combination of source composition, fluid transport capacity, and limited thorium remobilization in this near-source, hydrocarbon-rich environment. Correlations between U and high field strength elements (Sn, W) point to a highly evolved granitic origin, with Altyn granitoids likely supplying the copper. Sulfur isotopes show a clear bimodal distribution: one group exhibits heavy δ³⁴S values (+6.9‰ to +18.5‰), while the other shows extremely light values (–36.0‰ to –44.6‰). The light group reflects bacterial sulfate reduction in shallow strata, supported by framboidal pyrite textures, whereas the heavy group corresponds to surface-derived sulfate reduced at hydrocarbon-associated redox fronts, rather than direct incorporation of deep H₂S. The lack of intermediate δ³⁴S values indicates that two discrete sulfur reduction mechanisms coexisted within the same deposit, refining genetic models for uranium mineralization in petroliferous basins and challenging frameworks that invoke a single dominant sulfur source. Full article