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11 pages, 2533 KB  
Article
Characterization of Pimpinella anisum Germplasm: Diversity Available for Agronomic Performance and Essential Oil Content and Composition
by Pierluigi Reveglia, Eleonora Barilli, María José Cobos, Maria Claudia López-Orozco and Diego Rubiales
Agronomy 2026, 16(3), 285; https://doi.org/10.3390/agronomy16030285 - 23 Jan 2026
Abstract
Anise (Pimpinella anisum L.) is one of the most important annual herbs of the Apiaceae family, widely cultivated in southern Spain. Their seeds are highly valued for culinary uses and for producing quality essential oils widely used in food and beverage products, [...] Read more.
Anise (Pimpinella anisum L.) is one of the most important annual herbs of the Apiaceae family, widely cultivated in southern Spain. Their seeds are highly valued for culinary uses and for producing quality essential oils widely used in food and beverage products, as well as for industry, medicinal, and cosmetics applications. This study investigates the seed yield and essential oil content within a set of 50 anise accessions from worldwide origin, as well as their composition by GC–MS and GC–FID analysis. Accessions showed significant differences in the agronomic parameters measured, including plant height (cm), seed yield (kg ha−1), and the Harvest Index (%), with accessions PA_87 (Spain), PA_47 (Greece), and PA_21 (unknown origin) being the most performant. Essential oil (EO) content varied between 0.8% and 5.7% across different genotypes, resulting in EO production values ranging from 0.1 to 300 kg ha−1. Trans-anethole was identified as the dominant terpene, comprising 84.4% to 94.4% of the content, followed by eugenol (1.4% to 5.5%) and α-muurolene (1.4% to 7.2%). PCA analysis identified five distinct groups and one outlier, influenced by minor terpenes. Indeed, there was a strong negative correlation between estragole and pseudoisoeugenyl 2-methylbutyrate. This study underscores the significance of minor terpenes, which play crucial roles in defining unique aniseed chemotypes, allowing for the selection of cultivars optimized for specific uses in food, cosmetics, and pharmaceuticals. Additionally, these findings emphasize the impact of cultivar genetics on agronomic traits and EO profiles, suggesting the need for further research to optimize plant growth and yield and EO quality. Full article
(This article belongs to the Section Crop Breeding and Genetics)
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35 pages, 920 KB  
Review
Hemp (Cannabis sativa L.) Phytochemicals and Their Potential in Agrochemical, Cosmetic, and Food Industries: A Review
by Daniela Trono
Int. J. Mol. Sci. 2026, 27(3), 1146; https://doi.org/10.3390/ijms27031146 - 23 Jan 2026
Abstract
Hemp is a high-yield crop traditionally cultivated for fiber used in products such as paper, textiles, ropes, and animal bedding, and more recently for sustainable applications in biofuels, insulation, and bioplastics. Beyond fiber, hemp is rich in phytochemicals. More than 500 compounds including [...] Read more.
Hemp is a high-yield crop traditionally cultivated for fiber used in products such as paper, textiles, ropes, and animal bedding, and more recently for sustainable applications in biofuels, insulation, and bioplastics. Beyond fiber, hemp is rich in phytochemicals. More than 500 compounds including cannabinoids, terpenes, phenolics, phytosterols, and tocopherols are accumulated in leaves, flowers, and seeds, which are typically considered waste products in the fiber industry. These compounds exhibit antioxidant, anti-inflammatory, neuroprotective, and antimicrobial properties, which have stimulated research into their pharmaceutical potential. However, hemp phytochemicals also find applications in other industrial sectors, including agrochemistry as natural insecticides, cosmetics for skin and hair care, and food and dietary supplements due to their associated health benefits. In light of this, the present review aims to give an overview of the available literature on the most common applications of hemp tissues, hemp extract, and purified hemp phytochemicals in agrochemical, cosmetic, and food sectors. This will be helpful to critically assess the current state of knowledge in this field and contribute to the ongoing debate over the natural and sustainable applications of hemp by-products. Full article
(This article belongs to the Collection Feature Papers in Bioactives and Nutraceuticals)
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20 pages, 4247 KB  
Article
Effects of Milling-Medium Physicochemical Properties on Particle-Size Reduction and Surface Properties of Illite During Wet Ball Milling
by Nayeon Lee, Hyerin Lee, Yujin Jeong and Jin Hyun Lee
Minerals 2026, 16(1), 116; https://doi.org/10.3390/min16010116 - 22 Jan 2026
Abstract
Illite, a clay mineral, is used in diverse fields such as agriculture, cosmetics, and the food-related industry due to its many advantages, including biocompatibility, UV protection, antibacterial activity, high adsorption capacity for hazardous substances, and cost-effectiveness. However, its relatively large size, broad size [...] Read more.
Illite, a clay mineral, is used in diverse fields such as agriculture, cosmetics, and the food-related industry due to its many advantages, including biocompatibility, UV protection, antibacterial activity, high adsorption capacity for hazardous substances, and cost-effectiveness. However, its relatively large size, broad size distribution, and irregular morphology limit its broader applications. This study investigated the control of particle size and distribution during wet ball milling (WBM) using five media—acetone, ethanol, water, aqueous NaCl solution, and aqueous phosphoric acid solution—over milling times of 2–10 h. Prolonged milling progressively reduced particle size and narrowed the size distribution. Acetone and ethanol exhibited notably superior size-reduction performance compared with the aqueous systems, among which phosphoric acid solution showed the least effectiveness, likely attributed to variations in their physicochemical properties, including viscosity (η) and surface tension (σ), and in their interfacial interactions with illite. Optimal milling in acetone for 10 h resulted in the smallest particles (~700 nm), the narrowest distribution, the largest specific surface area, and the highest moisture retention. Overall, these findings demonstrate that the physicochemical properties of the milling medium, which govern WBM efficiency through fluid dynamics and particle–medium interactions, thereby determine the size and distribution of milled particles. Full article
(This article belongs to the Collection Clays and Other Industrial Mineral Materials)
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23 pages, 1077 KB  
Review
Rheology, Texture Analysis and Tribology for Sensory Prediction and Sustainable Cosmetic Design
by Giovanni Tafuro, Alessia Costantini and Alessandra Semenzato
Cosmetics 2026, 13(1), 25; https://doi.org/10.3390/cosmetics13010025 - 22 Jan 2026
Abstract
The cosmetic industry is undergoing a deep transformation driven by rapid innovation, evolving consumer expectations, and increasing demands for sustainability. Formulators are required to design products that combine functional efficacy, stability, and appealing sensory properties while adopting environmentally responsible strategies. Traditional empirical and [...] Read more.
The cosmetic industry is undergoing a deep transformation driven by rapid innovation, evolving consumer expectations, and increasing demands for sustainability. Formulators are required to design products that combine functional efficacy, stability, and appealing sensory properties while adopting environmentally responsible strategies. Traditional empirical and sensory-based approaches, though valuable, are often limited by high costs, time, subjectivity and lack of reproducibility. In this context, instrumental techniques provide an objective and predictive means to optimize product performance. Rheology, texture analysis, and tribology offer complementary insights into the structure, mechanical behavior, and interfacial phenomena of cosmetic formulations, all of which are closely linked to application behavior and sensory perception. Their integration enables a quantitative correlation between formulation composition, process conditions, and tactile performance. This review critically examines recent advances in the integrated use of rheology, texture analysis and tribology in cosmetic science, highlighting their role in sensory prediction, stability assessment, scale-up and eco-design. Together, these instrumental approaches support a more data-driven and innovation-oriented formulation paradigm, enabling database development and predictive modeling. Future research should prioritize database expansion, in vivo validation and machine learning integration to further improve sensory prediction and accelerate the design of advanced cosmetic formulations. Full article
(This article belongs to the Special Issue Feature Papers in Cosmetics in 2025)
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45 pages, 1829 KB  
Article
Horticultural Systems and Species Diversity of Roses in Classical Antiquity: Integrating Archaeological, Iconographic, and Literary Evidence from Ancient Greece and Rome
by Diego Rivera, Julio Navarro, Inmaculada Camarero, Javier Valera, Diego-José Rivera-Obón and Concepción Obón
Horticulturae 2026, 12(1), 118; https://doi.org/10.3390/horticulturae12010118 - 21 Jan 2026
Abstract
Roses held profound cultural and economic significance in ancient Greece and Rome, yet comprehensive documentation of their species diversity, cultivation practices, and horticultural innovations remains fragmented across archaeological, iconographic, and textual sources. This multidisciplinary study synthesizes evidence from classical texts, archaeological remains including [...] Read more.
Roses held profound cultural and economic significance in ancient Greece and Rome, yet comprehensive documentation of their species diversity, cultivation practices, and horticultural innovations remains fragmented across archaeological, iconographic, and textual sources. This multidisciplinary study synthesizes evidence from classical texts, archaeological remains including recently identified rose stem fragments from Oplontis, and iconographic materials—including frescoes, coins, and mosaics—to reconstruct the horticultural systems and cultural landscape of roses in classical antiquity. Analysis of literary sources, particularly Theophrastus’s fourth-century BCE taxonomic descriptions, reveals systematic cultivation of diverse rose varieties with flowers ranging from white to deep crimson, including yellow variants, characterized by morphologies from simple to double forms and valued for fragrance intensity and re-blooming capacity. Archaeological evidence from sites such as Paestum, Pompeii, and Oplontis, including pollen samples, preserved wood fragments with diagnostic prickle patterns, and fresco representations, documents commercial rose production and specialized cultivation techniques that demonstrate significantly greater morphological diversity than textual sources alone indicate. Field research and collection documentation establish the origins of Mediterranean rose cultivation, while iconographic analysis identifies roses in religious ceremonies, festivals, and daily life contexts. Textual sources provide detailed propagation methods, seasonal management practices, and evidence of Mediterranean hybridization events, alongside extensive documentation of medicinal and cosmetic applications. Economic analysis reveals specialized trade networks, commercial production centers, and diverse applications in perfumery, garland making, and pharmaceutical industries. This research establishes that Greek and Roman civilizations developed sophisticated rose cultivation systems integrating botanical selection, horticultural innovation, and cultural symbolism that directly influenced medieval and Renaissance practices and informed modern trait categorization systems. These findings demonstrate the foundational role of classical antiquity in European rose heritage, revealing how ancient horticultural knowledge, species diversification through hybridization, and cultivation techniques created an unbroken transmission that shaped contemporary rose industries and established conservation priorities for this horticultural heritage. Full article
(This article belongs to the Section Floriculture, Nursery and Landscape, and Turf)
14 pages, 1502 KB  
Article
Demethylation and Acetylation Modification of Alkali Lignin and Their Potential Applications in Sunscreen
by Jianan Hu, Yunni Zhan and Xuelian Zhou
Polymers 2026, 18(2), 286; https://doi.org/10.3390/polym18020286 - 21 Jan 2026
Abstract
In order to improve the utilization of alkali lignin (AL) as an effective component for ultraviolet (UV) shielding, demethylation and acetylation modification were carried out to improve the UV absorption performance of lignin. Then, lignin-based sunscreens were successfully prepared by mixing the modified [...] Read more.
In order to improve the utilization of alkali lignin (AL) as an effective component for ultraviolet (UV) shielding, demethylation and acetylation modification were carried out to improve the UV absorption performance of lignin. Then, lignin-based sunscreens were successfully prepared by mixing the modified lignin and commercial cream without UV shielding ingredients. The modified alkali lignin was comprehensively characterized in terms of its molecular weight, functional groups and structural properties by GPC, UV spectroscopy and 31P NMR. The results showed that the Mw of all three lignin feedstocks (AL, ALMeOH and ALAcetone) was decreased with prolonged demethylation time. Compared to the original feedstock, demethylated AL had a darker color and improved UV absorption performance due to the increased phenolic hydroxyl content (approximately 4.35 mmol/g). 31P-NMR spectra showed that the guaiacyl phenolic hydroxyl content decreased rapidly after acetylation, causing the sample color to become lighter. Among all lignin-based sunscreens, DALAcetone achieved the highest SPF value of 11.23, a 69.4% increase over its pre-reaction level and a 7.58-fold enhancement compared to the original lignin. In summary, this study opens a promising avenue for repurposing industrial lignin as a sustainable biomaterial in high-value sectors like UV-blocking agents and cosmetic formulations. Full article
(This article belongs to the Special Issue Valorization of Polymers in Wood)
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27 pages, 4668 KB  
Review
Macaúba (Acrocomia aculeata) as a Sustainable Alternative for the Bioindustry: A Bibliometric Review of Applications as Phytochemicals, Bioactives, and Biodiesel
by Lucas Costa da Silva, Maria Vanderly Nascimento Cavalcante, Mauricio Dorneles Lima, Bruna Araújo de Sousa, Ângella Eduarda da Silva Sousa, Alisson Justino Alves da Silva, Nair Silva Macêdo, Zildene de Sousa Silveira, Francisco Nascimento Pereira Junior, Francisco Assis Bezerra da Cunha, Luciana Medeiros Bertini and Maria Alexsandra de Sousa Rios
Sustainability 2026, 18(2), 1035; https://doi.org/10.3390/su18021035 - 20 Jan 2026
Abstract
This research aimed to conduct a bibliometric review on Acrocomia aculeata (Jacq.) Lodd. ex Mart., popularly known as “macaúba”, a palm tree of the Arecaceae family with great potential to promote sustainable practices. The review focused on the applications associated with [...] Read more.
This research aimed to conduct a bibliometric review on Acrocomia aculeata (Jacq.) Lodd. ex Mart., popularly known as “macaúba”, a palm tree of the Arecaceae family with great potential to promote sustainable practices. The review focused on the applications associated with the oil, pulp, and almonds of the fruit, products that can be used in industries such as food, cosmetics, and bioenergy, contributing to the development of more ecological production chains with less environmental impact. Data were collected from the Scopus, Web of Science, and ScienceDirect databases for publications related to phytochemical and bioactive aspects, while only Web of Science was used for data on energy aspects. The documents found were analyzed in the VOSviewer software (version 1.6.20), allowing the creation of bibliometric networks (clusters) and tables on scientific production. The analyses included authors, co-authors, countries, institutions, journal sources, and keywords. For phytochemical and bioactive aspects, the search resulted in 1026 articles, of which 261 were selected after applying the exclusion criteria. For energy aspects, 99 publications were found. Based on the data, it was possible to analyze the existing research on A. aculeata, identifying the state of the research and possible gaps in studies related to this oilseed. The results highlight the importance of macaúba as a sustainable alternative for diversifying agricultural and bioindustrial products, promoting the bioeconomy and contributing to the mitigation of environmental impacts. In addition, the research allowed us to identify the universities and researchers most dedicated to this species, their main results and the areas that still require investment to advance research. Thus, A. aculeata emerges as a relevant option to strengthen sustainable practices in key sectors, integrating economic, social, and environmental benefits. Full article
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19 pages, 1987 KB  
Review
Potential Bioactive Function of Microbial Metabolites as Inhibitors of Tyrosinase: A Systematic Review
by Sofia Barcenas-Giraldo, Vanessa Baez-Leguizamon, Laura Barbosa-Gonzalez, Angelica Leon-Rodriguez, Yovani Marrero-Ponce and Luis Diaz
Int. J. Mol. Sci. 2026, 27(2), 1016; https://doi.org/10.3390/ijms27021016 - 20 Jan 2026
Abstract
Tyrosinase (EC 1.14.18.1) is a binuclear copper enzyme responsible for the rate-limiting steps of melanogenesis, catalyzing the hydroxylation of L-tyrosine and oxidation of L-DOPA into o-quinones that polymerize melanin. Beyond its physiological role in pigmentation, tyrosinase is also implicated in food browning and [...] Read more.
Tyrosinase (EC 1.14.18.1) is a binuclear copper enzyme responsible for the rate-limiting steps of melanogenesis, catalyzing the hydroxylation of L-tyrosine and oxidation of L-DOPA into o-quinones that polymerize melanin. Beyond its physiological role in pigmentation, tyrosinase is also implicated in food browning and oxidative stress–related disorders, making it a key target in cosmetic, food, and biomedical industries. This systematic review, conducted following PRISMA guidelines, aimed to identify and analyze microbial metabolites with tyrosinase inhibitory potential as sustainable alternatives to conventional inhibitors such as hydroquinone and kojic acid. Literature searches in Scopus and Web of Science (March 2025) yielded 156 records; after screening and applying inclusion criteria, 11 studies were retained for analysis. The inhibitors identified include indole derivatives, phenolic acids, peptides, and triterpenoids, mainly produced by fungi (e.g., Ganoderma lucidum, Trichoderma sp.), actinobacteria (Streptomyces, Massilia), and microalgae (Spirulina, Synechococcus). Reported IC50 values ranged from micromolar to milli-molar levels, with methyl lucidenate F (32.23 µM) and p-coumaric acid (52.71 mM). Mechanisms involved competitive and non-competitive inhibition, as well as gene-level regulation. However, methodological heterogeneity, the predominance of mushroom tyrosinase assays, and limited human enzyme validation constrain translational relevance. Computational modeling, site-directed mutagenesis, and molecular dynamics are proposed to overcome these limitations. Overall, microbial metabolites exhibit promising efficacy, stability, and biocompatibility, positioning them as emerging preclinical candidates for the development of safer and more sustainable tyrosinase inhibitors. Full article
(This article belongs to the Special Issue Recent Advances in the Biological Function of Tyrosinase)
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15 pages, 1720 KB  
Article
Chemical Characterization of Extracts Derived from Apple, Sour Cherry, and Sweet Cherry Seed Oils
by Marek Szmigielski, Marek Domin, Piotr Kiczorowski, Marta Krajewska, Jolanta Piekut, Marzena Smolewska and Małgorzata Szczepanik
Agriculture 2026, 16(2), 255; https://doi.org/10.3390/agriculture16020255 - 19 Jan 2026
Viewed by 31
Abstract
Numerous sectors of the food processing and oleochemical industries require oils with specific physicochemical properties. Fruit processing generates substantial waste potentially containing valuable raw materials for oil extraction. The significant volumes of apples and cherries processed in Poland prompted an assessment of their [...] Read more.
Numerous sectors of the food processing and oleochemical industries require oils with specific physicochemical properties. Fruit processing generates substantial waste potentially containing valuable raw materials for oil extraction. The significant volumes of apples and cherries processed in Poland prompted an assessment of their seeds’ suitability as oil sources. Seed dry matter, protein, and oil content were determined. The extracted oils were analyzed for acid value (AV), peroxide value (PV), oxidative stability, fatty acid composition, and sterol and tocopherol content. The predominant higher fatty acids identified in the sour cherry and sweet cherry kernel oils were linoleic acid (C18:2, n-6), with mean concentrations of 45.82% and 29.23%, respectively, and oleic acid (C18:1, n-9), accounting for 41.54% and 46.59%, respectively. Additional fatty acids detected included palmitic acid C16:0 (6.23% and 5.91%), palmitoleic acid C16:1, n-7 (0.29%), stearic acid C18:0 (1.36% and 3.11%), arachidic acid C20:0 (1.13%), α-eleostearic acid C18:3 (5.07% and 9.48%), and α-linolenic acid C18:3, n-3 (4.09%). Given the substantial proportion of the oil fraction containing numerous potentially biologically active compounds, including nutritionally valuable fatty acids, tocopherols, and phytosterols, apple, sour cherry, and sweet cherry seeds demonstrate considerable potential as raw materials for applications in the food, pharmaceutical, and cosmetics industries. Full article
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24 pages, 1959 KB  
Review
Licorice (Glycyrrhiza glabra): Botanical Aspects, Multisectoral Applications, and Valorization of Industrial Waste for the Recovery of Natural Fiber in a Circular Economy Perspective
by Luigi Madeo, Anastasia Macario, Federica Napoli and Pierantonio De Luca
Fibers 2026, 14(1), 14; https://doi.org/10.3390/fib14010014 - 19 Jan 2026
Viewed by 18
Abstract
Licorice (Glycyrrhiza glabra) is a perennial herb traditionally valued for its aromatic and therapeutic properties. In recent years, however, growing attention has shifted toward the technical and environmental potential of the plant’s industrial by-products, particularly the fibrous material left after extraction. [...] Read more.
Licorice (Glycyrrhiza glabra) is a perennial herb traditionally valued for its aromatic and therapeutic properties. In recent years, however, growing attention has shifted toward the technical and environmental potential of the plant’s industrial by-products, particularly the fibrous material left after extraction. This review integrates botanical knowledge with engineering and industrial perspectives, highlighting the role of licorice fiber in advancing sustainable innovation. The natural fiber obtained from licorice roots exhibits notable physical and mechanical qualities, including lightness, biodegradability, and compatibility with bio-based polymer matrices. These attributes make it a promising candidate for biocomposites used in green building and other sectors of the circular economy. Developing efficient recovery processes requires collaboration across disciplines, combining expertise in plant science, materials engineering, and industrial technology. The article also examines the economic and regulatory context driving the transition toward more circular and traceable production models. Increasing interest from companies, research institutions, and public bodies in valorizing licorice fiber and its derivatives is opening new market opportunities. Potential applications extend to agroindustry, eco-friendly cosmetics, bioeconomy, and sustainable construction. By linking botanical insights with innovative waste management strategies, licorice emerges as a resource capable of supporting integrated, competitive, and environmentally responsible industrial practices. Full article
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20 pages, 3400 KB  
Article
Standardized Hydroxytyrosol-Enriched Olive Pomace Juice Modulates Metabolic and Neurotrophic Signaling Pathways to Attenuate Neuroinflammation and Protect Neuronal Cells
by Ye-Lim You, Ha-Jun Byun, Namgil Kang, Min Soo Lee, Jeong-In Lee, Ilbum Park and Hyeon-Son Choi
Molecules 2026, 31(2), 336; https://doi.org/10.3390/molecules31020336 - 19 Jan 2026
Viewed by 50
Abstract
Olive pomace (OP), a by-product of olive oil production, is a sustainable resource rich in bioactive compounds with potential applications in cosmetics and pharmaceuticals. This study investigates the protective effects of olive pomace juice (OPJ) against H2O2-induced neuronal damage [...] Read more.
Olive pomace (OP), a by-product of olive oil production, is a sustainable resource rich in bioactive compounds with potential applications in cosmetics and pharmaceuticals. This study investigates the protective effects of olive pomace juice (OPJ) against H2O2-induced neuronal damage and LPS-induced inflammatory responses in HT22 and BV2 cells, respectively. OPJ suppressed H2O2-induced cell death and exerted anti-apoptotic effects by reducing the BAX/BCL2 ratio and caspase-3 cleavage. OPJ also mitigated neurodegenerative hallmarks by decreasing amyloid fibrils formation and inhibiting β-secretase and acetylcholinesterase (AChE) activity. Mechanistically, OPJ enhanced antioxidant response by upregulating Nrf2 and its downstream molecule HO-1, along with increasing mRNA levels of antioxidant enzymes, including catalase, SOD1, and GPx. OPJ further activated AMPKα–SIRT1–PGC1α signaling and CREB–BDNF–TrkB signaling, suggesting modulation of key antioxidant, anti-apoptotic, and neurotrophic pathways. In BV2 cells, OPJ downregulated pro-inflammatory cytokines (IL-6 and IL-1β) and decreased iNOS and COX-2 expression through suppression of NF-κB and MAPK signaling pathways. HPLC analysis identified hydroxytyrosol (10.92%) as the major active compound in OPJ, which compared with tyrosol (2.18%), and hydroxytyrosol exhibited greater neuroprotective and anti-inflammatory effects than tyrosol. This study highlights the potential of OPJ and its major compound, hydroxytyrosol, as functional agents for mitigating neurodegeneration-related cellular response, supporting its application in the food and pharmaceutical industries. Full article
(This article belongs to the Special Issue Bioactive Compounds in Foods and Their By-Products)
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23 pages, 5037 KB  
Article
Experimental Valorization of Recycled Palm Oil in Topical Formulations: Preparation, Characterization, and Antimicrobial Assessment
by Paula Rusu, Andreea Creteanu, Alina-Mirela Ipate, Maricel Danu, Mirela-Fernanda Zaltariov, Daniela Rusu, Cristina Gabriela Tuchilus, Gladiola Tantaru and Gabriela Lisa
Molecules 2026, 31(2), 335; https://doi.org/10.3390/molecules31020335 - 19 Jan 2026
Viewed by 55
Abstract
Sustainable strategies for revalorizing food industry by-products are increasingly relevant in the development of modern experimental dermato-cosmetic formulations. In this study, two semisolid cosmetic creams (R10 and EM-R10) were designed using recycled palm oil—physically purified after intensive frying—as the lipid phase. The recycled [...] Read more.
Sustainable strategies for revalorizing food industry by-products are increasingly relevant in the development of modern experimental dermato-cosmetic formulations. In this study, two semisolid cosmetic creams (R10 and EM-R10) were designed using recycled palm oil—physically purified after intensive frying—as the lipid phase. The recycled oil was incorporated strictly within a controlled experimental framework and does not imply cosmetic-grade regulatory compliance. The formulations incorporated distinct bioactive profiles: R10 combined apricot and pineapple extracts with lime essential oil, while EM-R10 integrated fir bud and green tea extracts alongside the same essential oil. Both preparations contained Fragard as a preservative and niacinamide and panthenol as vitaminic components. The physicochemical properties of the formulations were assessed through rheology, confocal microscopy, ATR-FTIR, SEM, DSC, and contact angle measurements. Antimicrobial activity was evaluated against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans using disk diffusion and broth microdilution assays. The results demonstrate that, despite partial thermal degradation, recycled palm oil retains modified structural features that influence formulation-related properties relevant to topical systems. EM-R10 showed superior spreadability, adhesion, stability, and diffusion-related performance, as well as improved antimicrobial activity, within the investigated experimental conditions, highlighting recycled palm oil as a promising sustainable lipid phase for experimental dermato-cosmetic formulations, pending further purification, toxicological evaluation, and regulatory compliance assessment. Full article
(This article belongs to the Section Applied Chemistry)
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19 pages, 1571 KB  
Review
Recent Progress in Curcumin Extraction, Synthesis, and Applications: A Comprehensive Review
by Qirui Meng, Feng Xiao, Dahai Jiang, Wenxuan Jiang, Wenze Lin, Huiliang Gan, Tong Ye, Jianchun Jiang and Liming Lu
Foods 2026, 15(2), 354; https://doi.org/10.3390/foods15020354 - 18 Jan 2026
Viewed by 153
Abstract
Curcumin, a natural polyphenol derived from Curcuma longa L., exhibits diverse biological activities including anti-inflammatory, anticancer, and antioxidant effects, making it a versatile candidate for food, feed, pharmaceutical, and cosmetic applications. However, its industrial application is hindered by low bioavailability, poor water solubility, [...] Read more.
Curcumin, a natural polyphenol derived from Curcuma longa L., exhibits diverse biological activities including anti-inflammatory, anticancer, and antioxidant effects, making it a versatile candidate for food, feed, pharmaceutical, and cosmetic applications. However, its industrial application is hindered by low bioavailability, poor water solubility, and high production costs. This review comprehensively summarizes the latest advances in curcumin’s physicochemical properties, production routes (phytoextraction, chemical synthesis, and microbial biosynthesis), and wide applications. Compared with existing reviews, this work emphasizes quantitative benchmarking of production methods (yield, productivity, and environmental metrics), critical evaluation of application feasibility including regulatory hurdles and clinical evidence, and actionable future directions for industrial scalability. We systematically analyze the advantages, limitations, economic and environmental trade-offs of each production route, and highlight recent innovations in bioavailability enhancement and metabolic engineering. This review aims to provide a holistic theoretical and technical framework for accelerating curcumin’s sustainable development and commercialization in high-value products. Full article
(This article belongs to the Section Food Engineering and Technology)
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13 pages, 667 KB  
Article
Quantitative Assessment of Total Aerobic Viable Counts in Apitoxin-, Royal-Jelly-, Propolis-, Honey-, and Bee-Pollen-Based Products Through an Automated Growth-Based System
by Harold A. Prada-Ramírez, Raquel Gómez-Pliego, Humberto Zardo, Willy-Fernando Cely-Veloza, Ericsson Coy-Barrera, Rodrigo Palacio-Beltrán, Romel Peña-Romero, Sandra Gonzalez-Alarcon, Juan Camilo Fonseca-Acevedo, Juan Pablo Montes-Tamara, Lina Nieto-Celis, Ruth Dallos-Acosta, Tatiana Gonzalez, David Díaz-Báez and Gloria Inés Lafaurie
Microorganisms 2026, 14(1), 218; https://doi.org/10.3390/microorganisms14010218 - 17 Jan 2026
Viewed by 152
Abstract
Bee-derived products such as apitoxin, royal jelly, propolis, bee pollen, and honey are increasingly being used as part of cosmetic products because all of them contain a large number of bioactive compounds with antioxidant, anti-inflammatory, antimicrobial, and regenerative properties, which enable them to [...] Read more.
Bee-derived products such as apitoxin, royal jelly, propolis, bee pollen, and honey are increasingly being used as part of cosmetic products because all of them contain a large number of bioactive compounds with antioxidant, anti-inflammatory, antimicrobial, and regenerative properties, which enable them to be used for therapeutic purposes. The aim of this investigation was to assess the performance of an automated growth-based system in order to make a quantitative examination of the total aerobic viable counts in bee-derived personal care products using NF-TVC vials that contained a nutrient-based medium with dextrose as the carbon source. According to USP general chapter <1223>, pivotal validation criteria such as linearity, equivalence of results, operative range, precision, accuracy, ruggedness, limit of quantification, and limit of detection have demonstrated that the automated system can be used for a reliable total aerobic viable count. Moreover, the actual research demonstrated that polysorbates efficiently block the antimicrobiological potential of bioactive compounds, such as phenols, flavonoids, enzymes, peptides, and fatty acids, which naturally occur in apitoxin, royal jelly, propolis, bee pollen, and honey, allowing for efficient microorganism recovery from the bee-made products tested. Therefore, this AGBS could be applied efficiently within the cosmetic industry to assess the total aerobic viable count in bee-derived products such as capillary treatments, toothpaste, and anti-aging cream, affording several benefits associated with faster product release into the market. Full article
(This article belongs to the Section Antimicrobial Agents and Resistance)
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21 pages, 1329 KB  
Review
Valorization of Chestnut By-Products: Extraction, Bioactivity, and Applications of Shells, Spiny Burs, and Leaves
by Stefania Lamponi, Roberta Barletta and Annalisa Santucci
Life 2026, 16(1), 140; https://doi.org/10.3390/life16010140 - 15 Jan 2026
Viewed by 180
Abstract
The European chestnut (Castanea sativa Mill.) industry generates substantial amounts of underutilized biomass, including shells, leaves, and spiny burs. Distinguishing itself from existing literature, this review presents a novel, integrated life-science analysis that redefines these by-products as a complementary ‘bioactive triad’, ranging [...] Read more.
The European chestnut (Castanea sativa Mill.) industry generates substantial amounts of underutilized biomass, including shells, leaves, and spiny burs. Distinguishing itself from existing literature, this review presents a novel, integrated life-science analysis that redefines these by-products as a complementary ‘bioactive triad’, ranging from metabolic regulators to anti-virulence agents, rather than interchangeable sources of polyphenols. Although traditionally discarded, these by-products are rich sources of polyphenols, ellagitannins, and flavonoids, with promising potential for nutraceutical, cosmetic, and pharmaceutical applications. This review examines recent advances in the valorization of chestnut by-products, focusing on extraction strategies, chemical profiles, and biological activities. Shell valorization has increasingly shifted toward green extraction technologies, such as subcritical water extraction and deep eutectic solvents, which strongly influence bioactive recovery and composition. Chestnut leaves emerge as a sustainable resource enriched in hydrolysable tannins with anti-inflammatory and quorum sensing-inhibitory properties, particularly relevant for dermatological applications. Spiny burs, often the most phenolic-rich fraction, display marked antioxidant activity and the ability to potentiate conventional antibiotics against pathogens such as Helicobacter pylori. Despite these promising features, major challenges remain, including cultivar-dependent chemical variability, the predominance of in vitro evidence, and safety concerns related to the accumulation of potentially toxic elements. Overall, while chestnut by-products represent valuable resources within circular bioeconomy frameworks, their successful industrial and practical translation will require standardized extraction protocols, robust bioavailability assessments, and well-designed in vivo and clinical studies to ensure safety and efficacy. Full article
(This article belongs to the Section Plant Science)
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