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Feature Paper
Article

13 Citations

3,143 Views

13 Pages

The Effects of Shear Force-Based Processing of Lipoaspirates on White Adipose Tissue and the Differentiation Potential of Adipose Derived Stem Cells

Andreas Eigenberger,
Oliver Felthaus,
Thomas Schratzenstaller,
Silke Haerteis,
Kirsten Utpatel and
Lukas Prantl

Cells2022, 11(16), 2543;https://doi.org/10.3390/cells11162543

16 August 2022

Autologous lipotransfer is a promising method for tissue regeneration, because white adipose tissue contains a heterogeneous cell population, including mesenchymal stem cells, endothelial cells, immune cells, and adipocytes. In order to improve the o...

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Article

1 Citations

990 Views

15 Pages

The Influence of Sedimentation on the Composition of the Lipoaspirate and the Effects on Further Mechanical Processing

Andreas Eigenberger,
Oliver Felthaus,
Alexander Bartsch,
Tom Schimanski,
Kirsten Utpatel and
Lukas Prantl

Cells2025, 14(8), 601;https://doi.org/10.3390/cells14080601

16 April 2025

Manual processing of lipoaspirate can enhance stem cell concentration, thereby improving the take rate, which still represents a major challenge in autologous fat transfer. However, since the preparation consists of many manual steps that are difficu...

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Review

16 Citations

3,274 Views

11 Pages

Cell-Enriched Lipotransfer (CELT) Improves Tissue Regeneration and Rejuvenation without Substantial Manipulation of the Adipose Tissue Graft

Lukas Prantl,
Andreas Eigenberger,
Ruben Reinhard,
Andreas Siegmund,
Kerstin Heumann and
Oliver Felthaus

Cells2022, 11(19), 3159;https://doi.org/10.3390/cells11193159

8 October 2022

The good availability and the large content of adult stem cells in adipose tissue has made it one of the most interesting tissues in regenerative medicine. Although lipofilling is one of the most frequent procedures in plastic surgery, the method sti...

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Article

5 Citations

4,471 Views

13 Pages

Mechanical Stress Improves Fat Graft Survival by Promoting Adipose-Derived Stem Cells Proliferation

Jeong Jin Chun,
Jiyeon Chang,
Shindy Soedono,
Jieun Oh,
Yeong Jin Kim,
Syeo Young Wee,
Kae Won Cho and
Chang Yong Choi

Int. J. Mol. Sci.2022, 23(19), 11839;https://doi.org/10.3390/ijms231911839

6 October 2022

Cell-assisted lipotransfer (CAL), defined as co-transplantation of aspirated fat with enrichment of adipose-derived stem cells (ASCs), is a novel technique for cosmetic and reconstructive surgery to overcome the low survival rate of traditional fat g...

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Article

1,700 Views

20 Pages

Integrated Fluidic Platform for Washing and Mechanical Processing of Lipoaspirate for Downstream Fat Grafting and Regenerative Applications

David Zalazar,
Jiayi Feng,
Derek A. Banyard,
Marzieh Aliaghaei,
Alan D. Widgerow and
Jered B. Haun

Bioengineering2025, 12(9), 918;https://doi.org/10.3390/bioengineering12090918

26 August 2025

Autologous fat grafting of human lipoaspirate (LA) is increasingly used in reconstructive and cosmetic surgery for lipofilling and stem cell-rich “nanofat” reinjection for regenerative medicine. While commercial devices (e.g., REVOLVE and...

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