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7 Results Found

  • Article
  • Open Access
2 Citations
4,210 Views
8 Pages

The Use of Cavitron Ultrasonic Surgical Aspirator for High-Risk Neuroblastoma with Image-Defined Risk Factors in Children

  • Luca Pio,
  • Florent Guérin,
  • Cristina Martucci,
  • Helene Martelli,
  • Frédéric Gauthier and
  • Sophie Branchereau

2 January 2023

Aim of the study: The cavitron ultrasonic surgical aspirator (CUSA) has gained popularity in adult surgical oncology, but its application in children is limited to liver surgery and neurosurgical procedures. The complete resection of neuroblastoma wi...

  • Article
  • Open Access
2 Citations
2,545 Views
13 Pages

11 August 2023

In centrally located lung tumors, salvage pulmonary resections pose challenges due to adhesions between the pulmonary parenchyma, chest wall, and hilum. This study aimed to investigate the surgical outcomes associated with Cavitron Ultrasonic Surgica...

  • Article
  • Open Access
3 Citations
2,898 Views
15 Pages

27 October 2021

Liver transplantation is the most effective treatment for end-stage cirrhosis. However, due to serious donor shortages, new treatments to replace liver transplantation are sorely needed. Recent studies have focused on novel therapeutic methods using...

  • Article
  • Open Access
2 Citations
1,894 Views
17 Pages

The aim of this work is to analyse the effectiveness of the medical use of the Cavitron Ultrasonic Surgical Aspirator (CUSA) in microsurgical treatment of Intramedullary Spinal Cord Tumors (IMSCTs), with a focus on the thermo-mechanical effects on ne...

  • Article
  • Open Access
41 Citations
4,757 Views
22 Pages

Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients

  • Susannah Hallal,
  • Saeideh Ebrahim Khani,
  • Heng Wei,
  • Maggie Yuk Ting Lee,
  • Hao-Wen Sim,
  • Joanne Sy,
  • Brindha Shivalingam,
  • Michael E. Buckland and
  • Kimberley L. Alexander-Kaufman

Extracellular vesicles (EVs) play key roles in glioblastoma (GBM; astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood-brain-barrier into the periphery carrying GBM molecules, including s...

  • Article
  • Open Access
1 Citations
1,113 Views
29 Pages

Proteomic Analysis of the Low Molecular Mass Fraction of Newly Diagnosed and Recurrent Glioblastoma CUSA Fluid: A Pilot Investigation of the Peptidomic Profile

  • Alexandra Muntiu,
  • Federica Vincenzoni,
  • Diana Valeria Rossetti,
  • Andrea Urbani,
  • Giuseppe La Rocca,
  • Alessio Albanese,
  • Edoardo Mazzucchi,
  • Alessandro Olivi,
  • Giovanni Sabatino and
  • Claudia Desiderio

Glioblastoma multiforme (GBM) is a highly aggressive, treatment-resistant grade IV brain tumor with poor prognosis that grows rapidly and invades surrounding tissues, complicating surgery and frequently recurring. Although the crucial role of endogen...

  • Article
  • Open Access
10 Citations
3,694 Views
27 Pages

Glioblastoma CUSA Fluid Protein Profiling: A Comparative Investigation of the Core and Peripheral Tumor Zones

  • Giuseppe La Rocca,
  • Giorgia Antonia Simboli,
  • Federica Vincenzoni,
  • Diana Valeria Rossetti,
  • Andrea Urbani,
  • Tamara Ius,
  • Giuseppe Maria Della Pepa,
  • Alessandro Olivi,
  • Giovanni Sabatino and
  • Claudia Desiderio

23 December 2020

The present investigation aimed to characterize the protein profile of cavitating ultrasound aspirator fluid of newly diagnosed and recurrent glioblastoma comparing diverse zones of collection, i.e., tumor core and tumor periphery, with the aid of 5-...