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Keywords = calibration test

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25 pages, 5388 KiB  
Article
Numerical and Experimental Evaluation of Axial Load Transfer in Deep Foundations Within Stratified Cohesive Soils
by Şahin Çaglar Tuna
Buildings 2025, 15(15), 2723; https://doi.org/10.3390/buildings15152723 (registering DOI) - 1 Aug 2025
Abstract
This study presents a numerical and experimental evaluation of axial load transfer mechanisms in deep foundations constructed in stratified cohesive soils in İzmir, Türkiye. A full-scale bi-directional static load test equipped with strain gauges was conducted on a barrette pile to investigate depth-dependent [...] Read more.
This study presents a numerical and experimental evaluation of axial load transfer mechanisms in deep foundations constructed in stratified cohesive soils in İzmir, Türkiye. A full-scale bi-directional static load test equipped with strain gauges was conducted on a barrette pile to investigate depth-dependent mobilization of shaft resistance. A finite element model was developed and calibrated using field-observed load–settlement and strain data to replicate the pile–soil interaction and deformation behavior. The analysis revealed a shaft-dominated load transfer behavior, with progressive mobilization concentrated in intermediate-depth cohesive layers. Sensitivity analysis identified the undrained stiffness (Eu) as the most influential parameter governing pile settlement. A strong polynomial correlation was established between calibrated Eu values and SPT N60, offering a practical tool for preliminary design. Additionally, strain energy distribution was evaluated as a supplementary metric, enhancing the interpretation of mobilization zones beyond conventional stress-based methods. The integrated approach provides valuable insights for performance-based foundation design in layered cohesive ground, supporting the development of site-calibrated numerical models informed by full-scale testing data. Full article
(This article belongs to the Section Building Structures)
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27 pages, 5743 KiB  
Article
In-Field Load Acquisitions on a Variable Chamber Round Baler Using Instrumented Hub Carriers and a Dynamometric Towing Pin
by Filippo Coppola, Andrea Ruffin and Giovanni Meneghetti
Appl. Sci. 2025, 15(15), 8579; https://doi.org/10.3390/app15158579 (registering DOI) - 1 Aug 2025
Abstract
In this work, the load spectra acting in the vertical direction on the hub carriers and in the horizontal longitudinal direction on the drawbar of a trailed variable chamber round baler were evaluated. To this end, each hub carrier was instrumented with appropriately [...] Read more.
In this work, the load spectra acting in the vertical direction on the hub carriers and in the horizontal longitudinal direction on the drawbar of a trailed variable chamber round baler were evaluated. To this end, each hub carrier was instrumented with appropriately calibrated strain gauge bridges. Similarly, the baler was equipped with a dynamometric towing pin, instrumented with strain gauge sensors and calibrated in the laboratory, which replaced the original pin connecting the baler and the tractor during the in-field load acquisitions. In both cases, the calibration tests returned the relationship between applied forces and output signals of the strain gauge bridges. Multiple in-field load acquisitions were carried out under typical maneuvers and operating conditions. The synchronous acquisition of a video via an onboard camera and Global Positioning System (GPS) signal allowed to observe the behaviour of the baler in correspondence of particular trends of the vertical and horizontal loads and to point out the most demanding maneuver in view of the fatigue resistance of the baler. Finally, through the application of a rainflow cycle counting algorithm according to ASTM E1049-85, the load spectrum for each maneuver was derived. Full article
(This article belongs to the Section Mechanical Engineering)
15 pages, 6663 KiB  
Patent Summary
Modernization of the DISA 55D41 Wind Tunnel for Micro-Scale Probe Testing
by Emilia Georgiana Prisăcariu, Iulian Vlăducă, Oana Maria Dumitrescu, Sergiu Strătilă and Raluca Andreea Roșu
Inventions 2025, 10(4), 66; https://doi.org/10.3390/inventions10040066 (registering DOI) - 1 Aug 2025
Abstract
Originally introduced in the 1960s by DISA Elektronik as a calibration tunnel for hot-wire anemometers, the Type 55D41 has now been reengineered into a versatile and modern aerodynamic test platform. While retaining key legacy components, such as the converging nozzle and the 55D42 [...] Read more.
Originally introduced in the 1960s by DISA Elektronik as a calibration tunnel for hot-wire anemometers, the Type 55D41 has now been reengineered into a versatile and modern aerodynamic test platform. While retaining key legacy components, such as the converging nozzle and the 55D42 power unit, the upgraded system features a redesigned modular test section with optical-grade quartz windows. This enhancement enables compatibility with advanced flow diagnostics and visualization methods, including PTV, DIC, and schlieren imaging. The modernized facility maintains the precision and flow stability that made the original design widely respected, while expanding its functionality to meet the demands of contemporary experimental research. Its architecture supports the aerodynamic characterization of micro-scale static pressure probes used in aerospace, propulsion, and micro gas turbine applications. Special attention is given to assessing the influence of probe tip geometry (e.g., conical, ogive), port positioning, and stem interference on measurement accuracy. Full article
(This article belongs to the Section Inventions and Innovation in Advanced Manufacturing)
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11 pages, 634 KiB  
Article
Comparative Analysis of a Rapid Quantitative Immunoassay to the Reference Methodology for the Measurement of Blood Vitamin D Levels
by Gary R. McLean, Samson Soyemi, Oluwafunmito P. Ajayi, Sandra Fernando, Wiktor Sowinski-Mydlarz, Duncan Stewart, Sarah Illingworth, Matthew Atkins and Dee Bhakta
Methods Protoc. 2025, 8(4), 85; https://doi.org/10.3390/mps8040085 (registering DOI) - 1 Aug 2025
Abstract
Vitamin D is the only vitamin that is conditionally essential, as it is synthesized from precursors after UV light exposure, whilst also being obtained from the diet. It has numerous health benefits, with deficiency becoming a major concern globally, such that dietary supplementation [...] Read more.
Vitamin D is the only vitamin that is conditionally essential, as it is synthesized from precursors after UV light exposure, whilst also being obtained from the diet. It has numerous health benefits, with deficiency becoming a major concern globally, such that dietary supplementation has more recently achieved vital importance to maintain satisfactory levels. In recent years, measurements made from blood have, therefore, become critical to determine the status of vitamin D levels in individuals and the larger population. Tests for vitamin D have routinely relied on laboratory analysis with sophisticated equipment, often being slow and costly, whilst rapid immunoassays have suffered from poor specificity and sensitivity. Here, we have evaluated a new rapid immunoassay test on the market (Rapi-D & IgLoo) to quickly and accurately measure vitamin D levels in small capillary blood specimens and compared this to measurements made using the standard laboratory method of liquid chromatography and mass spectrometry. Our results show that vitamin D can be measured very quickly and over a broad range using the new method, as well as correlate relatively well with standard laboratory testing; however, it cannot be fully relied upon currently to accurately diagnose deficiency or sufficiency in individuals. Our statistical and comparative analyses find that the rapid immunoassay with digital quantification significantly overestimates vitamin D levels, leading to diminished diagnosis of vitamin D deficiency. The speed and simplicity of the rapid method will likely provide advantages in various healthcare settings; however, further calibration of this rapid method and testing parameters for improving quantification of vitamin D from capillary blood specimens is required before integration of it into clinical decision-making pathways. Full article
(This article belongs to the Section Omics and High Throughput)
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26 pages, 3030 KiB  
Article
Predicting Landslide Susceptibility Using Cost Function in Low-Relief Areas: A Case Study of the Urban Municipality of Attecoube (Abidjan, Ivory Coast)
by Frédéric Lorng Gnagne, Serge Schmitz, Hélène Boyossoro Kouadio, Aurélia Hubert-Ferrari, Jean Biémi and Alain Demoulin
Earth 2025, 6(3), 84; https://doi.org/10.3390/earth6030084 (registering DOI) - 1 Aug 2025
Abstract
Landslides are among the most hazardous natural phenomena affecting Greater Abidjan, causing significant economic and social damage. Strategic planning supported by geographic information systems (GIS) can help mitigate potential losses and enhance disaster resilience. This study evaluates landslide susceptibility using logistic regression and [...] Read more.
Landslides are among the most hazardous natural phenomena affecting Greater Abidjan, causing significant economic and social damage. Strategic planning supported by geographic information systems (GIS) can help mitigate potential losses and enhance disaster resilience. This study evaluates landslide susceptibility using logistic regression and frequency ratio models. The analysis is based on a dataset comprising 54 mapped landslide scarps collected from June 2015 to July 2023, along with 16 thematic predictor variables, including altitude, slope, aspect, profile curvature, plan curvature, drainage area, distance to the drainage network, normalized difference vegetation index (NDVI), and an urban-related layer. A high-resolution (5-m) digital elevation model (DEM), derived from multiple data sources, supports the spatial analysis. The landslide inventory was randomly divided into two subsets: 80% for model calibration and 20% for validation. After optimization and statistical testing, the selected thematic layers were integrated to produce a susceptibility map. The results indicate that 6.3% (0.7 km2) of the study area is classified as very highly susceptible. The proportion of the sample (61.2%) in this class had a frequency ratio estimated to be 20.2. Among the predictive indicators, altitude, slope, SE, S, NW, and NDVI were found to have a positive impact on landslide occurrence. Model performance was assessed using the area under the receiver operating characteristic curve (AUC), demonstrating strong predictive capability. These findings can support informed land-use planning and risk reduction strategies in urban areas. Furthermore, the prediction model should be communicated to and understood by local authorities to facilitate disaster management. The cost function was adopted as a novel approach to delineate hazardous zones. Considering the landslide inventory period, the increasing hazard due to climate change, and the intensification of human activities, a reasoned choice of sample size was made. This informed decision enabled the production of an updated prediction map. Optimal thresholds were then derived to classify areas into high- and low-susceptibility categories. The prediction map will be useful to planners in helping them make decisions and implement protective measures. Full article
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10 pages, 1103 KiB  
Article
Shock Wave Pressure Measurement and Calibration Method Based on Bar Pressure Sensor
by Yong-Xiang Shi, Ying-Cheng Peng, Yuan-Ding Xing, Xue-Jie Jiao, Xiao-Fei Huang and Ze-Qun Ba
Sensors 2025, 25(15), 4743; https://doi.org/10.3390/s25154743 (registering DOI) - 1 Aug 2025
Abstract
In order to correctly measure the shock wave pressure generated by a near-field explosion, and while considering the limitations of the measurement and calibration method of the current bar pressure sensor, an improved shock wave pressure measurement method was designed based on a [...] Read more.
In order to correctly measure the shock wave pressure generated by a near-field explosion, and while considering the limitations of the measurement and calibration method of the current bar pressure sensor, an improved shock wave pressure measurement method was designed based on a bar pressure sensor combined with photon Doppler velocimetry (PDV) and strain measurement. By measuring the strain on the pressure bar and the particle velocity on the rear-end face, the shock wave pressure applied on the front-end face of the pressure bar was calculated based on one-dimensional stress wave theory. On the other hand, a calibration method was designed to validate the reliability of the test system. Based on the split-Hopkinson pressure bar (SHPB) loading experiment, the transmission characteristics of stress wave in the bar and the accuracy of the system test results were verified. The results indicated that the stress wave measurement results were consistent with the one-dimensional elementary theoretical calculation results of stress wave propagation in different wave-impedance materials, and the peak deviation measured by PDV and strain measurement method was less than 1.5%, which proved the accuracy of the test method and the feasibility of the calibration method. Full article
(This article belongs to the Special Issue Sensors for Characterization of Energetic Materials Effects)
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19 pages, 950 KiB  
Article
How the Adoption of EVs in Developing Countries Can Be Effective: Indonesia’s Case
by Ida Nyoman Basmantra, Ngurah Keshawa Satya Santiarsa, Regina Dinanti Widodo and Caren Angellina Mimaki
World Electr. Veh. J. 2025, 16(8), 428; https://doi.org/10.3390/wevj16080428 (registering DOI) - 1 Aug 2025
Abstract
Indonesia’s worsening air pollution and traffic emissions have thrust electric vehicles (EVs) into the spotlight, but what really drives Indonesians to make the switch? This study integrates Protection Motivation Theory with green branding and policy frameworks to explain electric vehicle (EV) adoption in [...] Read more.
Indonesia’s worsening air pollution and traffic emissions have thrust electric vehicles (EVs) into the spotlight, but what really drives Indonesians to make the switch? This study integrates Protection Motivation Theory with green branding and policy frameworks to explain electric vehicle (EV) adoption in Indonesia. Using a nationwide survey (n = 986) and partial-least-squares structural-equation modeling, we test how environmental awareness, consumer expectancy, threat appraisal, and coping appraisal shape adoption both directly and through green brand image (GBI), while perceived policy incentives moderate the GBI–adoption link. The model accounts for 54% of the variance in adoption intention. These findings highlight that combining public awareness campaigns, compelling green brand messaging, and carefully calibrated policy incentives is essential for accelerating Indonesia’s transition to cleaner transport. Full article
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31 pages, 18320 KiB  
Article
Penetrating Radar on Unmanned Aerial Vehicle for the Inspection of Civilian Infrastructure: System Design, Modeling, and Analysis
by Jorge Luis Alva Alarcon, Yan Rockee Zhang, Hernan Suarez, Anas Amaireh and Kegan Reynolds
Aerospace 2025, 12(8), 686; https://doi.org/10.3390/aerospace12080686 (registering DOI) - 31 Jul 2025
Abstract
The increasing demand for noninvasive inspection (NII) of complex civil infrastructures requires overcoming the limitations of traditional ground-penetrating radar (GPR) systems in addressing diverse and large-scale applications. The solution proposed in this study focuses on an initial design that integrates a low-SWaP (Size, [...] Read more.
The increasing demand for noninvasive inspection (NII) of complex civil infrastructures requires overcoming the limitations of traditional ground-penetrating radar (GPR) systems in addressing diverse and large-scale applications. The solution proposed in this study focuses on an initial design that integrates a low-SWaP (Size, Weight, and Power) ultra-wideband (UWB) impulse radar with realistic electromagnetic modeling for deployment on unmanned aerial vehicles (UAVs). The system incorporates ultra-realistic antenna and propagation models, utilizing Finite Difference Time Domain (FDTD) solvers and multilayered media, to replicate realistic airborne sensing geometries. Verification and calibration are performed by comparing simulation outputs with laboratory measurements using varied material samples and target models. Custom signal processing algorithms are developed to extract meaningful features from complex electromagnetic environments and support anomaly detection. Additionally, machine learning (ML) techniques are trained on synthetic data to automate the identification of structural characteristics. The results demonstrate accurate agreement between simulations and measurements, as well as the potential for deploying this design in flight tests within realistic environments featuring complex electromagnetic interference. Full article
(This article belongs to the Section Aeronautics)
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7 pages, 2626 KiB  
Proceeding Paper
SpaFLEX: Field Campaign for Calibration and Validation of FLEX-S3 Mission Products
by Pedro J. Gómez-Giráldez, David Aragonés, Marcos Jiménez, Mª Pilar Cendrero-Mateo, Shari Van Wittenberghe, Juan José Peón, Adrián Moncholí-Estornell and Ricardo Díaz-Delgado
Eng. Proc. 2025, 94(1), 13; https://doi.org/10.3390/engproc2025094013 - 31 Jul 2025
Abstract
The FLEX-S3 mission by ESA will deliver key Level 2 products such as sun-induced chlorophyll fluorescence (SIF) and vegetation-reflected radiance. To validate these, the SpaFLEX project, funded by the Spanish Ministry of Science and Innovation, is developing a robust calibration and validation strategy [...] Read more.
The FLEX-S3 mission by ESA will deliver key Level 2 products such as sun-induced chlorophyll fluorescence (SIF) and vegetation-reflected radiance. To validate these, the SpaFLEX project, funded by the Spanish Ministry of Science and Innovation, is developing a robust calibration and validation strategy in Spain. This includes test site setup, instrument characterization, and sampling protocols. A field campaign was conducted in two Holm Oak forests in Teruel, analyzing Sentinel-2 spatial heterogeneity and collecting ground, UAV, and airborne data. The results support scaling procedures to match the 300 m pixel resolution of FLEX-S3, ensuring product accuracy and compliance with ESA standards. Full article
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20 pages, 4901 KiB  
Article
Study on the Adaptability of FBG Sensors Encapsulated in CNT-Modified Gel Material for Asphalt Pavement
by Tengteng Guo, Xu Guo, Yuanzhao Chen, Chenze Fang, Jingyu Yang, Zhenxia Li, Jiajie Feng, Jiahua Kong, Haijun Chen, Chaohui Wang, Qian Chen and Jiachen Wang
Gels 2025, 11(8), 590; https://doi.org/10.3390/gels11080590 (registering DOI) - 31 Jul 2025
Abstract
To prolong the service life of asphalt pavement and reduce its maintenance cost, a fiber Bragg grating (FBG) sensor encapsulated in carboxylated carbon nanotube (CNT-COOH)-modified gel material suitable for strain monitoring of asphalt pavement was developed. Through tensile and bending tests, the effects [...] Read more.
To prolong the service life of asphalt pavement and reduce its maintenance cost, a fiber Bragg grating (FBG) sensor encapsulated in carboxylated carbon nanotube (CNT-COOH)-modified gel material suitable for strain monitoring of asphalt pavement was developed. Through tensile and bending tests, the effects of carboxylated carbon nanotubes on the mechanical properties of gel materials under different dosages were evaluated and the optimal dosage of carbon nanotubes was determined. Infrared spectrometer and scanning electron microscopy were used to compare and analyze the infrared spectra and microstructure of carbon nanotubes before and after carboxyl functionalization and modified gel materials. The results show that the incorporation of CNTs-COOH increased the tensile strength, elongation at break, and tensile modulus of the gel material by 36.2%, 47%, and 17.2%, respectively, and increased the flexural strength, flexural modulus, and flexural strain by 89.7%, 7.5%, and 63.8%, respectively. Through infrared spectrum analysis, it was determined that carboxyl (COOH) and hydroxyl (OH) were successfully introduced on the surface of carbon nanotubes. By analyzing the microstructure, it can be seen that the carboxyl functionalization of CNTs improved the agglomeration of carbon nanotubes. The tensile section of the modified gel material is rougher than that of the pure epoxy resin, showing obvious plastic deformation, and the toughness is improved. According to the data from the calibration experiment, the strain and temperature sensitivity coefficients of the packaged sensor are 1.9864 pm/μm and 0.0383 nm/°C, respectively, which are 1.63 times and 3.61 times higher than those of the bare fiber grating. The results of an applicability study show that the internal structure strain of asphalt rutting specimen changed linearly with the external static load, and the fitting sensitivity is 0.0286 με/N. Combined with ANSYS finite element analysis, it is verified that the simulation analysis results are close to the measured data, which verifies the effectiveness and monitoring accuracy of the sensor. The dynamic load test results reflect the internal strain change trend of asphalt mixture under external rutting load, confirming that the encapsulated FBG sensor is suitable for the long-term monitoring of asphalt pavement strain. Full article
(This article belongs to the Special Issue Synthesis, Properties, and Applications of Novel Polymer-Based Gels)
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14 pages, 2727 KiB  
Article
A Multimodal MRI-Based Model for Colorectal Liver Metastasis Prediction: Integrating Radiomics, Deep Learning, and Clinical Features with SHAP Interpretation
by Xin Yan, Furui Duan, Lu Chen, Runhong Wang, Kexin Li, Qiao Sun and Kuang Fu
Curr. Oncol. 2025, 32(8), 431; https://doi.org/10.3390/curroncol32080431 - 30 Jul 2025
Abstract
Purpose: Predicting colorectal cancer liver metastasis (CRLM) is essential for prognostic assessment. This study aims to develop and validate an interpretable multimodal machine learning framework based on multiparametric MRI for predicting CRLM, and to enhance the clinical interpretability of the model through [...] Read more.
Purpose: Predicting colorectal cancer liver metastasis (CRLM) is essential for prognostic assessment. This study aims to develop and validate an interpretable multimodal machine learning framework based on multiparametric MRI for predicting CRLM, and to enhance the clinical interpretability of the model through SHapley Additive exPlanations (SHAP) analysis and deep learning visualization. Methods: This multicenter retrospective study included 463 patients with pathologically confirmed colorectal cancer from two institutions, divided into training (n = 256), internal testing (n = 111), and external validation (n = 96) sets. Radiomics features were extracted from manually segmented regions on axial T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI). Deep learning features were obtained from a pretrained ResNet101 network using the same MRI inputs. A least absolute shrinkage and selection operator (LASSO) logistic regression classifier was developed for clinical, radiomics, deep learning, and combined models. Model performance was evaluated by AUC, sensitivity, specificity, and F1-score. SHAP was used to assess feature contributions, and Grad-CAM was applied to visualize deep feature attention. Results: The combined model integrating features across the three modalities achieved the highest performance across all datasets, with AUCs of 0.889 (training), 0.838 (internal test), and 0.822 (external validation), outperforming single-modality models. Decision curve analysis (DCA) revealed enhanced clinical net benefit from the integrated model, while calibration curves confirmed its good predictive consistency. SHAP analysis revealed that radiomic features related to T2WI texture (e.g., LargeDependenceLowGrayLevelEmphasis) and clinical biomarkers (e.g., CA19-9) were among the most predictive for CRLM. Grad-CAM visualizations confirmed that the deep learning model focused on tumor regions consistent with radiological interpretation. Conclusions: This study presents a robust and interpretable multiparametric MRI-based model for noninvasively predicting liver metastasis in colorectal cancer patients. By integrating handcrafted radiomics and deep learning features, and enhancing transparency through SHAP and Grad-CAM, the model provides both high predictive performance and clinically meaningful explanations. These findings highlight its potential value as a decision-support tool for individualized risk assessment and treatment planning in the management of colorectal cancer. Full article
(This article belongs to the Section Gastrointestinal Oncology)
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21 pages, 4014 KiB  
Article
Optimized Mortar Formulations for 3D Printing: A Rheological Study of Cementitious Pastes Incorporating Potassium-Rich Biomass Fly Ash Wastes
by Raúl Vico Lujano, Luis Pérez Villarejo, Rui Miguel Novais, Pilar Hidalgo Torrano, João Batista Rodrigues Neto and João A. Labrincha
Materials 2025, 18(15), 3564; https://doi.org/10.3390/ma18153564 - 30 Jul 2025
Viewed by 86
Abstract
The use of 3D printing holds significant promise to transform the construction industry by enabling automation and customization, although key challenges remain—particularly the control of fresh-state rheology. This study presents a novel formulation that combines potassium-rich biomass fly ash (BFAK) with an air-entraining [...] Read more.
The use of 3D printing holds significant promise to transform the construction industry by enabling automation and customization, although key challenges remain—particularly the control of fresh-state rheology. This study presents a novel formulation that combines potassium-rich biomass fly ash (BFAK) with an air-entraining plasticizer (APA) to optimize the rheological behavior, hydration kinetics, and structural performance of mortars tailored for extrusion-based 3D printing. The results demonstrate that BFAK enhances the yield stress and thixotropy increases, contributing to improved structural stability after extrusion. In parallel, the APA adjusts the viscosity and facilitates material flow through the nozzle. Isothermal calorimetry reveals that BFAK modifies the hydration kinetics, increasing the intensity and delaying the occurrence of the main hydration peak due to the formation of secondary sulfate phases such as Aphthitalite [(K3Na(SO4)2)]. This behavior leads to an extended setting time, which can be modulated by APA to ensure a controlled processing window. Flowability tests show that BFAK reduces the spread diameter, improving cohesion without causing excessive dispersion. Calibration cylinder tests confirm that the formulation with 1.5% APA and 2% BFAK achieves the maximum printable height (35 cm), reflecting superior buildability and load-bearing capacity. These findings underscore the novelty of combining BFAK and APA as a strategy to overcome current rheological limitations in digital construction. The synergistic effect between both additives provides tailored fresh-state properties and structural reliability, advancing the development of a sustainable SMC and printable cementitious materials. Full article
(This article belongs to the Section Construction and Building Materials)
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14 pages, 1284 KiB  
Article
Non-Enzymatic Selective Detection of Histamine in Fishery Product Samples on Boron-Doped Diamond Electrodes
by Hiroshi Aoki, Risa Miyazaki and Yasuaki Einaga
Biosensors 2025, 15(8), 489; https://doi.org/10.3390/bios15080489 - 29 Jul 2025
Viewed by 137
Abstract
Histamine sensing that uses enzymatic reactions is the most common form of testing due to its selectivity for histamine. However, enzymes are difficult to store for long periods of time, and the inactivation of enzymes decreases the reliability of the results. In this [...] Read more.
Histamine sensing that uses enzymatic reactions is the most common form of testing due to its selectivity for histamine. However, enzymes are difficult to store for long periods of time, and the inactivation of enzymes decreases the reliability of the results. In this study, we developed a novel, quick, and easily operated histamine sensing technique that takes advantage of the histamine redox reaction and does not require enzyme-based processes. Because the redox potential of histamine is relatively high, we used a boron-doped diamond (BDD) electrode that has a wide potential window. At pH 8.4, which is between the acidity constant of histamine and the isoelectric point of histidine, it was found that an oxygen-terminated BDD surface successfully detected histamine, both selectively and exclusively. Measurements of the sensor’s responses to extracts from fish meat samples that contained histamine at various concentrations revealed that the sensor responds linearly to the histamine concentration, thus allowing it to be used as a calibration curve. The sensor was used to measure histamine in another fish meat sample treated as an unknown sample, and the response was fitted to the calibration curve to perform an inverse estimation. When estimated in this way, the histamine concentration matched the certified value within the range of error. A more detailed examination showed that the sensor response was little affected by the histidine concentration in the sample. The detection limit was 20.9 ppm, and the linear response range was 0–150 ppm. This confirms that this sensing method can be used to measure standard histamine concentrations. Full article
(This article belongs to the Special Issue Advanced Biosensors for Food and Agriculture Safety)
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18 pages, 4253 KiB  
Article
Testing Using the DCP Probe of a Subgrade Modeled from Difficult-to-Compact Sand in a Calibration Chamber
by Dariusz Tymosiak, Maria Jolanta Sulewska, Wanda Kokoszka, Marta Słowik, Ewa Błazik-Borowa, Dominik Ożóg and Monika Puchlik
Materials 2025, 18(15), 3548; https://doi.org/10.3390/ma18153548 - 29 Jul 2025
Viewed by 168
Abstract
The aim of the article is to analyze the possibilities of using a lightweight dynamic cone probe DCP to determine the quality of compaction of surface layers of embankments (from 0.10 m to approx. 0.80 m below ground level). For this purpose, comparative [...] Read more.
The aim of the article is to analyze the possibilities of using a lightweight dynamic cone probe DCP to determine the quality of compaction of surface layers of embankments (from 0.10 m to approx. 0.80 m below ground level). For this purpose, comparative tests of non-cohesive soil used for the construction of embankments were carried out using the DCP test and direct tests of the degree of compaction IS in a calibration chamber with the following dimensions: height 1.10 m and diameter 0.75 m. The subsoil was prepared from difficult-to-compact sand (Sa) with a uniformity coefficient of CU = 3.10 and curvature coefficient of CC = 0.99. The soil in the laboratory in the calibration chamber was compacted in layers using a vibratory plate compactor. A database for statistical analysis was obtained, n = 68 cases described by seven variables: z, ρ, w, ρd, IS, PI, N10(DCP). It was found that the DCP probe can be used to assess the degree of compaction of embankments made of non-cohesive soil, using the developed relationship IS = f(z, N10(DCP)). Full article
(This article belongs to the Section Construction and Building Materials)
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14 pages, 2191 KiB  
Article
AI-Based Ultrasound Nomogram for Differentiating Invasive from Non-Invasive Breast Cancer Masses
by Meng-Yuan Tsai, Zi-Han Yu and Chen-Pin Chou
Cancers 2025, 17(15), 2497; https://doi.org/10.3390/cancers17152497 - 29 Jul 2025
Viewed by 141
Abstract
Purpose: This study aimed to develop a predictive nomogram integrating AI-based BI-RADS lexicons and lesion-to-nipple distance (LND) ultrasound features to differentiate mass-type ductal carcinoma in situ (DCIS) from invasive ductal carcinoma (IDC) visible on ultrasound. Methods: The final study cohort consisted of 170 [...] Read more.
Purpose: This study aimed to develop a predictive nomogram integrating AI-based BI-RADS lexicons and lesion-to-nipple distance (LND) ultrasound features to differentiate mass-type ductal carcinoma in situ (DCIS) from invasive ductal carcinoma (IDC) visible on ultrasound. Methods: The final study cohort consisted of 170 women with 175 pathologically confirmed malignant breast lesions, including 26 cases of DCIS and 149 cases of IDC. LND and AI-based features from the S-Detect system (BI-RADS lexicons) were analyzed. Rare features were consolidated into broader categories to enhance model stability. Data were split into training (70%) and validation (30%) sets. Logistic regression identified key predictors for an LND nomogram. Model performance was evaluated using receiver operating characteristic (ROC) curves, 1000 bootstrap resamples, and calibration curves to assess discrimination and calibration. Results: Multivariate logistic regression identified smaller lesion size, irregular shape, LND ≤ 3 cm, and non-hypoechoic echogenicity as independent predictors of DCIS. These variables were integrated into the LND nomogram, which demonstrated strong discriminative performance (AUC = 0.851 training; AUC = 0.842 validation). Calibration was excellent, with non-significant Hosmer-Lemeshow tests (p = 0.127 training, p = 0.972 validation) and low mean absolute errors (MAE = 0.016 and 0.034, respectively), supporting the model’s accuracy and reliability. Conclusions: The AI-based comprehensive nomogram demonstrates strong reliability in distinguishing mass-type DCIS from IDC, offering a practical tool to enhance non-invasive breast cancer diagnosis and inform preoperative planning. Full article
(This article belongs to the Section Methods and Technologies Development)
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