3,972 Results Found

The aim of the work was to study the interaction between boron-rich boron carbide nanoparticles and selected tumor and immune phagocytic cells. Experiments were performed to investigate the feasibility of the application of boron carbide nanoparticle...

In this review, the history of boron’s early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed. This includes diazaborines, boronic acids, benzoxaboroles, boron clusters, and c...

Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical dr...

Boron neutron capture therapy (BNCT) is a cancer treatment with clinically demonstrated efficacy using boronophenylalanine (BPA) and sodium mercaptododecaborate (BSH). However, tumor tissue selectivity of BSH and retention of BPA in tumor cells is a...

Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT). The boronated amino acids synthesized thus far f...

Among the great variety of anti-cancer therapeutic strategies, boron neutron capture therapy (BNCT) represents a unique approach that doubles the targeting accuracy due to the precise positioning of a neutron beam and the addressed delivery of boron...

Boron neutron capture therapy (BNCT) is a binary type of radiotherapy for the treatment of cancer. Due to recent developments of neutron accelerators and their installation in some hospitals, BNCT is on the rise worldwide and is expected to have a si...

This study proposes an innovative process of low-temperature soda roasting followed by water leaching to extract boron and produce borax from boron-rich slag. To further enhance the leaching rate of boron, pretreatment of the boron-rich slag with the...

Siderophores are classically understood as microbial iron-acquisition metabolites: low-molecular-weight ligands secreted by bacteria to solubilize and transport Fe(III) under iron-limited conditions. In this review, we expand that paradigm by highlig...

Boron carbide is an extremely hard and lightweight material used in armor systems. Upon impact above the Hugoniot elastic limit (HEL), boron carbide loses strength and suddenly fails. Atomistic models suggest that boron-rich boron carbides could miti...

Boron Neutron Capture Therapy (BNCT) is a tumor cell-selective radiotherapy based on a nuclear reaction that occurs when the isotope boron-10 (¹⁰B) is radiated by low-energy thermal neutrons or epithermal neutrons, triggering a nuclear fission respon...

Boron neutron capture therapy (BNCT) is one of the most appealing radiotherapy modalities, whose localization can be further improved by the employment of boron-containing nanoformulations, but the fabrication of biologically friendly, water-dispersi...

The boron (Z = 5) element is unique. Boron-based (nano-)materials are equally unique. Accordingly, the present special issue is dedicated to crystalline boron-based (nano-)materials and gathers a series of nine review and research articles dealing wi...

Enhancement of the production yield of boron nitride nanotubes (BNNTs) with high purity was achieved using an amorphous boron-based precursor and a nozzle-type reactor. Use of a mixture of amorphous boron and Fe decreases the milling time for the pre...

Enriched boron-10 and its related compounds have great application prospects, especially in the nuclear industry. The chemical exchange rectification method is one of the most important ways to separate the ¹⁰B and ¹¹B isotope. However, a real-time m...

Sufficient boron-10 isotope (¹⁰B) accumulation by tumor cells is one of the main requirements for successful boron neutron capture therapy (BNCT). The inability of the clinically registered ¹⁰B-containing borophenylalanine (BPA) to maintain a high bo...

This review covers the application of cycloaddition reactions in forming the boron-containing compounds such as symmetric star-shaped boron-enriched dendritic molecules, nano-structured boron materials and aromatic boronic esters. The resulting boron...

In this research, we developed boron-rich nanoparticles that can be used for boron neutron capture therapy as potential carriers for boron delivery to cancerous tissues. Functionalized carbonated boron nitride nanostructures (CBNs) were successfully...

Boron carbide is one of the hardest materials in the world which can be synthesized by various methods. The most common one is a carbothermic or magnesiothermic reduction of B₂O₃ performed at high temperatures, where the obtained powder still require...

Boron neutron capture therapy (BNCT) is a binary cancer treatment that involves the irradiation of ¹⁰B-containing tumors with low-energy neutrons (thermal or epithermal). The alpha particles and recoiling Li nuclei that are produced in the ¹⁰B-captur...

Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods. Thus, to develop a novel and co...

Diamond as a templating substrate is largely unexplored, and the unique properties of diamond, including its large bandgap, thermal conductance, and lack of cytotoxicity, makes it versatile in emergent technologies in medicine and quantum sensing. Su...

Boron-doped graphite was prepared by the heat treatment of coke using B₄C powder as a graphitization catalyst to investigate the effects of the substitutional boron atoms on the interlayer spacing of graphite. Boron atoms can be successfully incorpor...

A boron-rich boron–carbide material (B_4+δC) was synthesized by spark plasma sintering of a ball-milled mixture of high-purity boron powder and graphitic carbon at a pressure of 7 MPa and a temperature of 1930 °C. This high-pressure, h...

The initial austenite grain size of boron microalloyed steel with three different amounts of boron (20, 40, and 60 ppm) was investigated under different heating temperatures (1150, 1100, and 1050 °C), and hot compression tests of samples in a wide ra...

As a significant parameter in tuning the structure and performance of the boron-doped diamond (BDD), the thickness was focused on the mediation of the boron doping level and electrochemical properties. BDD films with different thicknesses were deposi...

Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation. The recent initiation of BNCT clinical trials employing hospital-based accelerators rather...

Molecular topology provides a basis for the correlation of physical as well as chemical properties of a certain molecule. Irregularity indices are used as functions in the statistical analysis of the topological properties of certain molecular graphs...

Tourmaline, a boron-bearing mineral, has been extensively applied as a geothermometer, provenance indicator, and fluid-composition recorder in geological studies. In this paper, the decomposition capability of an HF-HNO₃–mannitol mixture for a...

Boron is an essential plant micronutrient taken up via the roots mostly in the form of boric acid. Its important role in plant metabolism involves the stabilization of molecules with cis-diol groups. The element is involved in the cell wall and membr...

The addition of boron (B) fertilizers to soils with low B content is required for augmenting crop yield. Therefore, it is imperative to have knowledge about the impact of long-term B addition at various dosages on crop yield and soil-B dynamics. A fi...

Drug delivery systems, which use components at the nanoscale level as diagnostic tools or to release therapeutic drugs to particular target areas in a regulated manner, are a fast-evolving field of science. The active pharmaceutical substance can be...

Borate is an essential material to numerous industries and even to individual countries’ economies, defense, and politics. Almost all industries need borates for production, and almost everybody needs their products. Borate is a compound that c...

In this work, a novel ceramic precursor containing boron, silicon, and nitrides (named SiBCN) was synthesized from liquid ceramic precursors. Additionally, its pyrolysis, microstructure, and chemical composition were studied at 1600 °C. The resul...

In this paper, a boron–mannitol complex wet acid digestion method proposed for the accurate determination of boron in silicate samples by inductively coupled plasma mass spectrometry (ICP-MS) was investigated in detail for the first time. With...

The adsorption separation and extraction of low-concentration boron from salt-lake brine have great significance. Magnetic separation avoids the problem of adsorbent granulation and improves the usage efficiency. The silicon-based adsorbents have att...

Background: Boron Neutron Capture Therapy (BNCT) is a binary approach to cancer therapy that requires accumulation of boron atoms preferentially in tumour cells. This can be achieved by using nanoparticles as boron carriers and taking advantage of th...

Chemical doping of boron atoms is essential to modify the electrical properties of graphene films. The synthesis of large-scale boron-doped graphene with high uniformity and good electrical properties is still a great challenge. To improve the qualit...

Due to the characteristics of high energy density and a high calorific value, boron has become a high-energy fuel and shows great potential to be a high-performance candidate for propellants. However, the wide applications of boron are still limited...

In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronat...

BODIPY compounds are important organic dyes with exceptional spectral and photophysical properties and numerous applications in different scientific fields. Their widespread applications have flourished due to their easy structural modifications, whi...

The single-center convergent close-coupling (CCC) method is applied to calculate positron scattering from boron. A model potential approach is utilized to extract the positronium formation, direct ionization, and values between the positronium format...

Despite its inconveniences, the most recognized method to extract boron from soils is that of hot water extraction (B_HW), which is used for diagnostics and recommendations. However, the Mehlich-3 (M3) method is widely used to extract and diagnose sev...

Boron is a trace element with multifaceted chemical and biological properties that underpin its emerging relevance in human health and medicinal chemistry. Although present in organisms at very low concentrations, boron participates in key physiologi...

Boron-containing compounds have made a significant impact on the field of medicinal chemistry since the discovery of Bortezomib (Velcade^®), a dipeptide boronic acid approved by the FDA in 2003 for the treatment of multiple myeloma. Since then, ov...

A standard goal of medicinal chemists has been to discover efficient and potent drug candidates with specific enzyme-inhibitor abilities. In this regard, boron-based bioactive compounds have provided amphiphilic properties to facilitate interaction w...

Development of new boron nanocarriers has been a crucial issue to be solved for advancing boron neutron capture therapy (BNCT) as an effective radiation treatment for cancers. The present study aimed to create a novel double-thermoresponsive boron-co...

The presence of a large number of boron atoms in boron clusters make them attractive tools for the treatment of cancer using boron neutron capture therapy (BNCT). Since the quantity of boron atoms present in the target cell directly affects the effec...

In this study, a Nocardia niigatensis strain was isolated from boron-rich mining soils in the Bigadiç region of Türkiye and comprehensively characterized. The primary aim of this study was to isolate boron-tolerant Nocardia species and ev...

Boron-doped organic compounds display unique properties as a result of the presence of an empty p orbital on boron and the ability to switch between a trigonal planar and a tetrahedral geometry. In recent years, they have found several applications n...