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28 Results Found

  • Article
  • Open Access
3,747 Views
12 Pages

30 September 2024

Background: The impact of and countermeasures for Ureaplasma spp. in neonates remain controversial. The aim of this study was to evaluate the associated perinatal factors that can predict the likelihood of respiratory tract Ureaplasma spp. colonizati...

  • Article
  • Open Access
4,967 Views
11 Pages

Evaluating the Antibiotic Resistance Patterns in Mycoplasma hominis and Ureaplasma spp. Infections in Salvador, Brazil

  • Sofia Lírio Santos Silva,
  • Larissa Vieira do Amaral,
  • Raissa Vieira do Amaral,
  • Maria Isabel Figueiredo Sousa,
  • Mauricio Freitas Batista,
  • Maria Betânia Toralles,
  • Caroline Alves Feitosa,
  • Galileu Barbosa Costa and
  • Viviane Matos Ferreira

Background/Objectives: Mycoplasma and Ureaplasma species are pathogens commonly associated with urogenital infections in sexually active individuals. Despite their clinical relevance, these organisms are less frequently studied than other sexually tr...

  • Article
  • Open Access
5 Citations
4,042 Views
9 Pages

Determination of In Vitro Antimicrobial Susceptibility for Lefamulin (Pleuromutilin) for Ureaplasma Spp. and Mycoplasma hominis

  • Oliver Spiller-Boulter,
  • Susanne Paukner,
  • Ian Boostrom,
  • Kirsty Sands,
  • Edward A. R. Portal and
  • Owen B. Spiller

9 November 2021

Lefamulin is the first of the pleuromutilin class of antimicrobials to be available for therapeutic use in humans. Minimum inhibitory concentrations of lefamulin were determined by microbroth dilution for 90 characterised clinical isolates (25 Ureapl...

  • Article
  • Open Access
12 Citations
6,006 Views
11 Pages

Maternal Vaginal Ureaplasma spp. Colonization in Early Pregnancy Is Associated with Adverse Short- and Long-Term Outcome of Very Preterm Infants

  • Judith Rittenschober-Böhm,
  • Tanja Habermüller,
  • Thomas Waldhoer,
  • Renate Fuiko,
  • Stefan M. Schulz,
  • Birgit Pimpel,
  • Katharina Goeral,
  • Armin Witt,
  • Angelika Berger and
  • Karin Pichler

Vaginal colonization with Ureaplasma (U.) spp. has been shown to be associated with adverse pregnancy outcome; however, data on neonatal outcome are scarce. The aim of the study was to investigate whether maternal vaginal colonization with U. spp. in...

  • Article
  • Open Access
2 Citations
3,556 Views
12 Pages

We investigated whether cervical Ureaplasma spp. colonization affects the intensity of inflammatory mediators in amniotic fluid retrieved during cesarean delivery in singleton preterm birth. One hundred fifty-three cases in singleton preterm birth wi...

  • Article
  • Open Access
6 Citations
4,280 Views
11 Pages

The Role of HPV and Non-HPV Sexually Transmitted Infections in Patients with Oropharyngeal Carcinoma: A Case Control Study

  • Barbara Kofler,
  • Johannes Laimer,
  • Emanuel Bruckmoser,
  • Teresa B. Steinbichler,
  • Annette Runge,
  • Volker H. Schartinger,
  • Dorothee von Laer and
  • Wegene Borena

8 May 2020

Background: Certain high-risk (hr) types of human papillomavirus (HPV) can cause cervical cancer in women and penile cancer in men. Hr-HPV can also cause cancers of the oropharynx and anus in both sexes. In the anal and cervical region, a contributio...

  • Article
  • Open Access
2 Citations
1,901 Views
26 Pages

Proinflammatory Cytokines in Women with PCOS in Atypical Pathogen Infections

  • Izabela Chudzicka-Strugała,
  • Iwona Gołębiewska,
  • Grzegorz Brudecki,
  • Wael Elamin,
  • Beata Banaszewska,
  • Marta Chudzicka-Adamczak,
  • Dominik Strugała and
  • Barbara Zwoździak

Background/Objectives: Polycystic ovary syndrome (PCOS) is one of the most frequently diagnosed endocrine and metabolic disorders in women of reproductive age before menopause. It is associated with excess androgens and ovarian dysfunction, reduced f...

  • Communication
  • Open Access
3 Citations
1,871 Views
8 Pages

Detection of Putative Virulence Genes alrgoiB, and goiC in Mycoplasma hominis Isolates from Austrian Patients

  • Iwona Lesiak-Markowicz,
  • Julia Walochnik,
  • Angelika Stary and
  • Ursula Fürnkranz

In Mycoplasma hominis, two genes (alr and goiB) have been found to be associated with the invasion of the amniotic cavity, and a single gene (goiC) to be associated with intra-amniotic infections and a high risk of preterm birth. The syntopic presenc...

  • Article
  • Open Access
2 Citations
3,013 Views
20 Pages

Identification of Mycoplasma Species in Cattle Associated with Bovine Respiratory Disease Mortality

  • Emanuele Carella,
  • Erika Messana,
  • Davide Mugetti,
  • Elena Biasibetti,
  • Marzia Pezzolato,
  • Simone Peletto,
  • Mattia Begovoeva and
  • Francesca Rossi

Approximately 30 distinct Mycoplasma species have been isolated from cattle, but only a few are pathogenic and can cause serious respiratory diseases. Consequently, this study aimed to identify Mycoplasma spp. infections in cattle with bovine respira...

  • Article
  • Open Access
12 Citations
5,280 Views
15 Pages

Ureaplasma Species Modulate Cytokine and Chemokine Responses in Human Brain Microvascular Endothelial Cells

  • Christine Silwedel,
  • Christian P. Speer,
  • Axel Haarmann,
  • Markus Fehrholz,
  • Heike Claus,
  • Nicolas Schlegel and
  • Kirsten Glaser

Ureaplasma species are common colonizers of the adult genitourinary tract and often considered as low-virulence commensals. Intraamniotic Ureaplasma infections, however, facilitate chorioamnionitis and preterm birth, and cases of Ureaplasma-induced n...

  • Article
  • Open Access
3 Citations
2,160 Views
15 Pages

Unveiling Hidden Risks: Intentional Molecular Screening for Sexually Transmitted Infections and Vaginosis Pathogens in Patients Who Have Been Exclusively Tested for Human Papillomavirus Genotyping

  • Fabiola Hernández-Rosas,
  • Manuel Rey-Barrera,
  • Flavio Hernández-Barajas,
  • Claudia Rangel-Soto,
  • Mariana Socorro García-González,
  • Shumeyker Susmith Franco-González and
  • Mercedes Piedad de León-Bautista

Human papillomavirus (HPV) is the most prevalent sexually transmitted infection (STI) worldwide, with popular screening methods including the Papanicolaou test and HPV genotyping. However, in clinical practice, coinfections with other pathogens are o...

  • Article
  • Open Access
5 Citations
3,327 Views
14 Pages

Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women

  • Fabiola Hernández-Rosas,
  • Manuel Rey-Barrera,
  • Ulises Conejo-Saucedo,
  • Erika Orozco-Hernández,
  • Liliana Maza-Sánchez,
  • Enrique Navarro-Vidal,
  • Yasmín López-Vera,
  • María del Carmen Ascencio-Gordillo and
  • Mercedes Piedad de León-Bautista

13 December 2021

Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG),...

  • Article
  • Open Access
1 Citations
4,163 Views
11 Pages

Antimicrobial Activity of N,N-Diethyldithiocarbamate against Ureaplasma parvum and Ureaplasma urealyticum

  • Małgorzata Biernat-Sudolska,
  • Danuta Rojek-Zakrzewska,
  • Kamil Drożdż and
  • Anna Bilska-Wilkosz

Ureaplasma species (Ureaplasma spp.) are commonly found as commensals in the human urogenital tracts, although their overgrowth can lead to infection in the urogenital tract and at distal sites. Furthermore, ureaplasmas lack a cell wall and do not sy...

  • Systematic Review
  • Open Access
2 Citations
2,100 Views
15 Pages

Does the Vaginal Microbiota Influence the Incidence of the Preterm Premature Rupture of Membranes?

  • Stepan Feduniw,
  • Natalia Zeber-Lubecka,
  • Michal Pruc,
  • Zuzanna Gaca,
  • Łukasz Szarpak and
  • Michal Ciebiera

18 September 2025

Introduction: The study aimed to provide a systematic review and analysis of previously reported studies investigating the association between the bacterial microbiome and the incidence of preterm premature rupture of membranes (PPROM). Material and...

  • Article
  • Open Access
1 Citations
1,053 Views
11 Pages

Prevalence of Sexually Transmitted Infections Among Cisgender Women Coming to a Walk-In Center

  • Gaia Catalano,
  • Tommaso Clemente,
  • Sara Diotallevi,
  • Riccardo Lolatto,
  • Benedetta Trentacapilli,
  • Martina Ranzenigo,
  • Elena Bruzzesi,
  • Paola Cinque,
  • Antonella Castagna and
  • Silvia Nozza

29 March 2025

The general female population is not considered a high-risk group for screening for sexually transmitted infections (STIs). This retrospective study describes the prevalence of Human Immunodeficiency Virus (HIV), Treponema pallidum (T. pallidum), Chl...

  • Article
  • Open Access
36 Citations
4,241 Views
13 Pages

Mycoplasma Co-Infection Is Associated with Cervical Cancer Risk

  • Cameron Klein,
  • Kandali Samwel,
  • Crispin Kahesa,
  • Julius Mwaiselage,
  • John T. West,
  • Charles Wood and
  • Peter C. Angeletti

28 April 2020

Tanzania faces one of the highest cervical cancer burdens in the world. Recent work has suggested that the bacterial family Mycoplasmataceae is associated with higher levels of human papillomavirus (HPV), human immunodeficiency virus (HIV), and pre-c...

  • Article
  • Open Access
1,283 Views
17 Pages

Placental Molecular Expression of Different Pathogenic Vaginal Infections

  • Daniela Roxana Matasariu,
  • Constantin Condac,
  • Victoria Bîrluțiu,
  • Ludmila Lozneanu,
  • Iuliana Elena Bujor,
  • Vasile Lucian Boiculese,
  • Mihai Sava and
  • Alexandra Ursache

This study evaluated the differential expression of four placental markers—vitamin D receptor (VDR), Cluster of Differentiation 44 (CD44), osteopontin (OPN), and cyclooxygenase-2 (COX-2)—in response to pathogens, which may contribute to o...

  • Article
  • Open Access
545 Views
17 Pages

No Histopathological Evidence of Inflammation Despite Molecular Detection of Schistosoma spp. and Sexually Transmitted Pathogens in Placental Parenchyma Specimens with Limited Membrane Sampling from West African Women with Uncomplicated Pregnancies

  • Jan Theile Suhren,
  • Gunnar Müller,
  • Torsten Feldt,
  • Mathurin Koffi,
  • Samuel Blay Nguah,
  • Carola Bindt,
  • Stephan Ehrhardt,
  • Dana Barthel,
  • Rebecca Hinz and
  • Kirsten Alexandra Eberhardt
  • + 5 authors

30 November 2025

Background: Placental infections caused by Schistosoma spp. and sexually transmitted microorganisms can adversely impact pregnancy outcomes. However, the association between molecular detection of these pathogens in placental tissue and corresponding...

  • Review
  • Open Access
62 Citations
16,650 Views
17 Pages

Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications

  • George Daskalakis,
  • Alexandros Psarris,
  • Antonios Koutras,
  • Zacharias Fasoulakis,
  • Ioannis Prokopakis,
  • Antonia Varthaliti,
  • Christina Karasmani,
  • Thomas Ntounis,
  • Ekaterini Domali and
  • Angeliki Papapanagiotou
  • + 3 authors

As the leading cause of neonatal morbidity and mortality, preterm birth is recognized as a major public health concern around the world. The purpose of this review is to analyze the connection between infections and premature birth. Spontaneous prete...

  • Article
  • Open Access
7 Citations
6,023 Views
13 Pages

Detection of Mycoplasma Contamination in Transplanted Retinal Cells by Rapid and Sensitive Polymerase Chain Reaction Test

  • Sunao Sugita,
  • Ayumi Hono,
  • Shoko Fujino,
  • Yoko Futatsugi,
  • Yuta Yunomae,
  • Norio Shimizu and
  • Masayo Takahashi

21 November 2021

Contamination of cells/tissues by infectious pathogens (e.g., fungi, viruses, or bacteria, including mycoplasma) is a major problem in cell-based transplantation. In this study, we tested a polymerase chain reaction (PCR) method to provide rapid, sim...

  • Article
  • Open Access
11 Citations
2,870 Views
16 Pages

Cervical HPV Infections, Sexually Transmitted Bacterial Pathogens and Cytology Findings—A Molecular Epidemiology Study

  • George Valasoulis,
  • Abraham Pouliakis,
  • Georgios Michail,
  • Ioulia Magaliou,
  • Christos Parthenis,
  • Niki Margari,
  • Christine Kottaridi,
  • Aris Spathis,
  • Danai Leventakou and
  • Ioannis G. Panayiotides
  • + 5 authors

14 November 2023

Prevalent cervical HPV infection and high-risk HPV persistence consequences have been extensively investigated in the literature; nevertheless, any causative interrelations of other sexually transmitted bacterial infections (STIs) with cervical HPV i...

  • Article
  • Open Access
4 Citations
2,507 Views
11 Pages

Molecular Exploration of Mycoplasma fermentans and Mycoplasma genitalium in Mexican Women with Cervicitis

  • Abraham David Bustos-López,
  • Marcos R. Escobedo-Guerra,
  • Marcela López-Hurtado,
  • Jesús Roberto Villagrana-Zesati,
  • Martha Valdés-Ramírez,
  • Silvia Giono-Cerezo and
  • Fernando M. Guerra-Infante

15 November 2024

Genital Mycoplasmas are implicated in adverse pregnancy outcomes and the development of infertility. However, the role of Mycoplasma fermentans in these outcomes has not been adequately studied; therefore, its participation in these sufferings requir...

  • Article
  • Open Access
8 Citations
3,260 Views
11 Pages

Dysbiotic Vaginal Microbiota Induces Preterm Birth Cascade via Pathogenic Molecules in the Vagina

  • AbuZar Ansari,
  • Young-Ah You,
  • Gain Lee,
  • Soo Min Kim,
  • Sun Wha Park,
  • Young Min Hur and
  • Young Ju Kim

11 January 2024

Dysbiotic vaginal microbiota (DVM) disturb the vaginal environment, including pH, metabolite, protein, and cytokine profiles. This study investigated the impact of DVM on the vaginal environment in 40 Korean pregnant women and identified predictable...

  • Article
  • Open Access
901 Views
10 Pages

Microbiota of Cervical Canal in Nine Patients Diagnosed with Ectopic Pregnancy: Case Series

  • Kinga Bednarek,
  • Katarzyna Wszołek,
  • Monika Szewc,
  • Mirosława Gałęcka,
  • Adrian Mruczyński,
  • Alan Bruszewski,
  • Marcin Wierzchowski,
  • Maciej Wilczak and
  • Karolina Chmaj-Wierzchowska

12 June 2025

Dysbiosis, or an altered microbiota composition, has been implicated in chronic endometrial inflammation and recurrent implantation failure. Despite growing research on the relationship between the genital microbiome and reproductive health, few stud...

  • Article
  • Open Access
11 Citations
3,931 Views
14 Pages

Analysis of Vaginal Microbiota Variations in the Third Trimester of Pregnancy and Their Correlation with Preterm Birth: A Case-Control Study

  • Catalin Prodan-Barbulescu,
  • Felix Bratosin,
  • Roxana Folescu,
  • Estera Boeriu,
  • Zoran Laurentiu Popa,
  • Cosmin Citu,
  • Adrian Ratiu,
  • Ovidiu Rosca and
  • Adrian Cosmin Ilie

This study conducted a detailed analysis of the vaginal microbiota in pregnant women to explore its correlation with preterm birth (PTB) outcomes. The primary objective was to identify microbial variations associated with increased PTB risk. Secondar...

  • Article
  • Open Access
1,282 Views
10 Pages

The Quantitative Detection of Urogenital Mycoplasmas in Men with Urolithiasis

  • Dominika Smolec,
  • Małgorzata Aptekorz,
  • Łukasz Filipczyk,
  • Zygmunt Gofron,
  • Jacek Zostawa,
  • Robert Smolec,
  • Tomasz J. Wąsik and
  • Alicja Ekiel

Urease-positive urogenital mycoplasmas are considered to be responsible for the formation of urinary stones. They are usually a part of the normal flora in the human urogenital tract, causing asymptomatic infections. However, many symptomatic infecti...

  • Article
  • Open Access
10 Citations
199 Views

Prevalence of Mycoplasma genitalium and Other Sexually-Transmitted Pathogens Among High-Risk Individuals in Greece

  • Paraskevi Chra,
  • Joseph Papaparaskevas,
  • Eleni Papadogeorgaki,
  • George Panos,
  • Michalis Leontsinidis,
  • George Arsenis and
  • Athanassios Tsakris

1 March 2018

Background: The aim of the present study was to determine the prevalence of Mycoplasma genitalium (MG) infection among individuals at high risk for sexually-transmitted diseases (STDs) at a major urban STD clinic in Athens, in view of the lack of dat...

  • Article
  • Open Access
7 Citations
4,343 Views
11 Pages

Screening for Vaginal and Endocervical Infections in the First Trimester of Pregnancy? A Study That Ignites an Old Debate

  • Leonie Toboso Silgo,
  • Sara Cruz-Melguizo,
  • María Luisa de la Cruz Conty,
  • María Begoña Encinas Pardilla,
  • María Muñoz Algarra,
  • Yolanda Nieto Jiménez,
  • Alexandra Arranz Friediger and
  • Óscar Martínez-Pérez

10 December 2021

Objectives: Vaginal and endocervical infections are considered a global health problem, especially after recent evidence of their association with preterm delivery and other adverse obstetric outcomes. Still, there is no consensus on the efficacy of...