Diagnosis and Management of Gynecological Diseases in 2025

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 234

Special Issue Editor


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Guest Editor
Department of Obstetrics and Gynecology, Kindai University Faculty of Medicine, Osaka, Japan
Interests: uterine lesions; hysteroscopy; laparoscopy
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Special Issue Information

Dear Colleagues,

This Special Issue highlights the latest advancements in the diagnosis and management of gynecological diseases, with a particular emphasis on innovative diagnostic techniques. Articles explore the use of cutting-edge imaging technologies, such as MRI and ultrasound, in detecting gynecological abnormalities with greater accuracy. Additionally, the role of molecular diagnostics, including genetic testing and biomarker analysis, is underscored for its potential to personalize treatment plans and improve patient outcomes. Overall, this Special Issue provides a comprehensive overview of the evolving diagnostic landscape in gynecological disease management.

Dr. Yasushi Kotani
Guest Editor

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Keywords

  • gynecological diseases
  • diagnosis
  • management strategies
  • obstetrics and gynecology
  • women’s health
  • clinical practice guidelines
  • reproductive health disorders
  • personalized treatment approaches

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Published Papers (1 paper)

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Research

11 pages, 3928 KiB  
Article
Quantitative Classification of Uterine Myoma Perfusion on DCE-MRI: Retrospective Analysis of Data and Clinical Implications
by Alan Bruszewski, Agnieszka Lach, Maciej Wilczak and Karolina Chmaj-Wierzchowska
Diagnostics 2025, 15(12), 1464; https://doi.org/10.3390/diagnostics15121464 - 9 Jun 2025
Abstract
The degree of vascularization of myomas plays an important role in both diagnosis and the selection of appropriate treatment. This is particularly relevant for minimally invasive therapies such as uterine artery embolization (UAE), high-intensity focused ultrasound (HIFU), or radiofrequency ablation (RFA) in uterine [...] Read more.
The degree of vascularization of myomas plays an important role in both diagnosis and the selection of appropriate treatment. This is particularly relevant for minimally invasive therapies such as uterine artery embolization (UAE), high-intensity focused ultrasound (HIFU), or radiofrequency ablation (RFA) in uterine myomas, as their effectiveness is highest in well-vascularized lesions. Background/Objectives: This study aimed to analyze the perfusion of uterine myomas using dynamic contrast-enhanced magnetic resonance imaging and to develop a new quantitative classification of lesion vascularization, referencing the Funaki classification. Methods: The study included 56 female patients. Three parameters were determined for each lesion: the maximum signal enhancement (Ratio), time to peak, and mean signal intensity (Mean). A KMeans cluster analysis (k = 3) was performed, dividing the data into three groups corresponding to Funaki types I–III. Results: Significant differences were observed between the groups. Type III myomas were found only in older patients, which may be relevant when qualifying patients for vascularization-targeted therapies such as HIFU or radiofrequency ablation. Conclusions: The proposed classification may serve as a basis for automating the assessment of myomas and supporting clinical decision-making. Full article
(This article belongs to the Special Issue Diagnosis and Management of Gynecological Diseases in 2025)
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