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Keywords = Resonant Mirrors

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24 pages, 6376 KB  
Article
Assigning Single-Crystal NMR Data to Crystallographic Sites for Symmetry-Affected Interaction Tensors: A Case Study of Sinhalite, MgAlBO4, by 11B and 27Al NMR Spectroscopy and DFT Calculations
by Jennifer Steinadler, Kristian Witthaut, Georg Krach, Rupert Hochleitner and Thomas Bräuniger
Crystals 2026, 16(6), 395; https://doi.org/10.3390/cryst16060395 - 17 Jun 2026
Viewed by 100
Abstract
The natural mineral sinhalite, MgAlBO4, was investigated by means of single-crystal NMR spectroscopy. In its orthorhombic space group, the aluminium and boron atoms occupy Wyckoff positions 4b and 4c, but the specific site symmetry of the boron atoms [...] Read more.
The natural mineral sinhalite, MgAlBO4, was investigated by means of single-crystal NMR spectroscopy. In its orthorhombic space group, the aluminium and boron atoms occupy Wyckoff positions 4b and 4c, but the specific site symmetry of the boron atoms situated on a mirror plane leads two only two instead of four magnetically inequivalent atoms per site. This structural feature also restricts the corresponding NMR interaction tensors and reduces known assignment ambiguities regarding the NMR resonances of 27Al and 11B to distinct atomic positions. Comparing the experimentally determined eigenvectors of the quadrupolar coupling tensors with the results of DFT calculations for the electric field gradients further condensed the remaining options and delivered the full quadrupolar coupling tensors for both nuclides in the crystal structure of sinhalite. Full article
(This article belongs to the Section Inorganic Crystalline Materials)
31 pages, 2442 KB  
Article
Magnetic Anomaly Detection Based on a Multi-Parameter-Constrained Mirror Dual-Branch Biased Monostable Stochastic Resonance System
by Rongxiang Xia, Mingxi Chen, Lizhi Hong, Zhiyuan Ai and Shaojie Ma
Sensors 2026, 26(12), 3776; https://doi.org/10.3390/s26123776 - 13 Jun 2026
Viewed by 222
Abstract
Magnetic anomaly detection is vulnerable to environmental noise and insufficient prior target information, making non-periodic anomaly signals difficult to detect at low-signal-to-noise-ratio (SNR) conditions. This paper proposes a detection method based on a multi-parameter-constrained mirror dual-branch biased monostable stochastic resonance (SR) system. Nonlinear [...] Read more.
Magnetic anomaly detection is vulnerable to environmental noise and insufficient prior target information, making non-periodic anomaly signals difficult to detect at low-signal-to-noise-ratio (SNR) conditions. This paper proposes a detection method based on a multi-parameter-constrained mirror dual-branch biased monostable stochastic resonance (SR) system. Nonlinear odd-order bias terms are introduced into the conventional biased monostable potential function to build a multi-parameter-controllable SR model. This improves regulation of potential-well width, depth, and wall morphology, enhancing noise-energy utilization and responses to non-periodic features. Considering peak-type, valley-type, and bipolar anomaly morphologies, a mirror dual-branch SR structure is developed to cooperatively detect features with different polarities. To preserve temporal waveforms and time–frequency structures during parameter optimization, a composite metric combining the correlation coefficient and wavelet-domain image structural similarity index is constructed. Multi-fidelity robust Bayesian optimization is used to obtain a unified robust parameter set for the magnetic anomaly signal family. Experiments with simulated colored noise and measured geomagnetic noise show that the proposed method effectively recovers magnetic anomaly features under strong noise. At −19 dB SNR, its detection probability remains above 80%. Compared with orthogonal basis function decomposition, empirical mode decomposition, and complete ensemble empirical mode decomposition with adaptive noise, the method achieves better noise suppression, feature preservation, and detection performance under low-SNR conditions. Full article
(This article belongs to the Section Physical Sensors)
17 pages, 7497 KB  
Article
Loss-Managed BIC-Derived GSST Metasurface for Robust Phase-Change-Tunable Mid-Infrared Transmission Suppression
by Zhi-Yuan Zheng and Ying Yu
Photonics 2026, 13(6), 531; https://doi.org/10.3390/photonics13060531 - 29 May 2026
Viewed by 219
Abstract
We propose a loss-managed BIC-derived GSST metasurface for robust phase-change-tunable mid-infrared transmission suppression. The metasurface consists of a SiO2 substrate, a Si grating layer, and an upper Si/Ge2Sb2Se4Te1 (GSST)/Si trilayer with an off-centered air slot. [...] Read more.
We propose a loss-managed BIC-derived GSST metasurface for robust phase-change-tunable mid-infrared transmission suppression. The metasurface consists of a SiO2 substrate, a Si grating layer, and an upper Si/Ge2Sb2Se4Te1 (GSST)/Si trilayer with an off-centered air slot. The slot plays a dual role: it breaks the mirror symmetry of the unit cell to convert a symmetry-protected bound state in the continuum into an externally accessible high-Q resonance, while reducing the effective GSST filling region to limit material-loss participation. Lossless eigenmode analysis confirms the BIC-derived origin of the resonance, with the quality factor following Qxdisp1.993. A crystalline-state loss-channel analysis further identifies xdisp=40nm as a finite-coupling operating point that preserves good up/down radiation balance, a large resonant amplitude factor, and a moderate-high quality factor under the fully crystalline GSST condition. Full-wave simulations show that the transmission-dip wavelength shifts from about 3.9568μm to about 3.9740μm as GSST evolves from the amorphous to the crystalline state, while the extracted quality factor remains in the range of 483–780 and the transmission minimum stays deeply suppressed throughout the phase-change trajectory. A two-port temporal coupled-mode theory analysis reveals that this persistent low-transmission state originates from destructive interference between the resonant and background transmission channels. Fabrication tolerance analysis shows that ±5% variations in GSST thickness and slot width, as well as moderate variations in the slot displacement, preserve the deep transmission suppression across GSST phase states, although the absolute resonance wavelength shifts with geometry. These results provide a practical strategy for balancing radiative coupling and material-loss participation in phase-change high-Q metasurfaces. Full article
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29 pages, 2786 KB  
Article
Enhanced Transmission Loss and Modal Coupling in Dual-Membrane Flexible-Shell Cylindrical Waveguides: A Rigorous Mode-Matching–Galerkin Framework
by Mohammed Alkinidri
Mathematics 2026, 14(10), 1761; https://doi.org/10.3390/math14101761 - 20 May 2026
Viewed by 209
Abstract
This paper develops an analytical treatment of vibro-acoustic wave propagation in a cylindrical waveguide containing two clamped elastic membranes and a central flexible-shell segment. The acoustic field obeys the time-harmonic Helmholtz equation, the shell motion is described by Donnell–Mushtari thin-shell theory under axisymmetric [...] Read more.
This paper develops an analytical treatment of vibro-acoustic wave propagation in a cylindrical waveguide containing two clamped elastic membranes and a central flexible-shell segment. The acoustic field obeys the time-harmonic Helmholtz equation, the shell motion is described by Donnell–Mushtari thin-shell theory under axisymmetric loading, and the membrane response is governed by classical membrane theory and incorporated through a tailored Galerkin scheme. The resulting coupled fluid–structure boundary-value problem is solved by the Mode-Matching Method: the acoustic potentials are expanded in orthogonal radial eigenfunctions within each subregion, and continuity of pressure, normal velocity, and structural displacement are enforced at every interface. The mirror symmetry of the configuration is exploited by an exact decomposition into symmetric and anti-symmetric sub-problems, each of which reduces to a truncated linear algebraic system of dimension 4N+4 for the unknown modal amplitudes. Acoustic power-balance identities provide a quantitative consistency check on the numerical implementation and diagnose convergence with respect to the truncation order; structural damping is accommodated through complex-modulus substitutions for the shell and the membrane tension without altering the algebraic structure of the system. The numerical results demonstrate that the dual-membrane configuration delivers transmission-loss values exceeding 25dB across the low-frequency band relevant to HVAC and automotive applications, with a representative plateau near 13dB at the reference geometry, through resonance-driven modal coupling between the acoustic field and the compliant interfaces. Parametric studies identify the excitation frequency, the inner-membrane radius, the shell radius, and the chamber length as effective design parameters for tuning the attenuation. The formulation furnishes a unified and computationally efficient analytical tool for predicting and optimising noise attenuation in flexibly coupled cylindrical duct systems. Full article
(This article belongs to the Section E4: Mathematical Physics)
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18 pages, 418 KB  
Article
Relationship of Susceptibility to Emotional Contagion with Automatic Emotion Processing and Emotional Competences
by Merle Welten, Anette Kersting and Thomas Suslow
Behav. Sci. 2026, 16(5), 811; https://doi.org/10.3390/bs16050811 - 19 May 2026
Viewed by 301
Abstract
Individuals differ in their susceptibility to emotional contagion, i.e., the automatic tendency to mirror and synchronize another person’s expressions and movements, resulting in shared emotional experiences. The objective of this research was to investigate how susceptibility to emotional contagion connects to automatic facial [...] Read more.
Individuals differ in their susceptibility to emotional contagion, i.e., the automatic tendency to mirror and synchronize another person’s expressions and movements, resulting in shared emotional experiences. The objective of this research was to investigate how susceptibility to emotional contagion connects to automatic facial emotion processing and emotional competences. An affective priming task using happy, angry, neutral, and blank faces was administered to a sample of 104 women with a mean age of 24.72 years (SD = 3.63). They completed self-report measures assessing susceptibility to positive and negative emotional contagion, alexithymia, trait emotional intelligence, affectivity, and depression. Although prime valence-congruent evaluative shifts were found in our sample, there were no correlations of susceptibility to positive and negative emotional contagion with affective priming effects. Susceptibility to positive emotion contagion was negatively correlated with alexithymia and positively with emotional intelligence. However, susceptibility to positive emotion contagion predicted only emotional intelligence (but not alexithymia), when controlling for relevant affect variables. Our findings indicate that emotional contagion susceptibility could be less strongly linked to automatic emotion perception than previously suggested. Moreover, the trait-like tendency to resonate with other people’s positive emotions seems to be linked to enhanced capacities in perceiving, interpreting, and regulating emotions. Full article
(This article belongs to the Section Social Psychology)
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14 pages, 2429 KB  
Article
Numerical Simulation of Optical Characteristics of the NPOM Nanostructure Based on Gold Nanocubes
by Genyi Fu and Lei Xu
Symmetry 2026, 18(5), 825; https://doi.org/10.3390/sym18050825 - 11 May 2026
Viewed by 289
Abstract
The design of metal nanoparticle-on-a-mirror (NPOM) provides a powerful strategy for optical enhancement in gap plasmonics. Here, we report a systematic numerical study on an NPOM structure composed of gold nanocubes (GNC) and a continuous gold film via the finite element method (FEM). [...] Read more.
The design of metal nanoparticle-on-a-mirror (NPOM) provides a powerful strategy for optical enhancement in gap plasmonics. Here, we report a systematic numerical study on an NPOM structure composed of gold nanocubes (GNC) and a continuous gold film via the finite element method (FEM). First, we simulated the near-electric field distribution of isolated GNC in a homogeneous medium and compared it with that of the GNC-based NPOM structure, revealing the dominant role of plasmon coupling in the gap region. Second, we systematically investigated the influence of the thickness of the dielectric layer between the GNC and the gold film on the optical enhancement characteristics in the gap region. The results show that the maximum electric field intensity of the resonance peak decays rapidly when the thickness of the dielectric layer is less than 2 nm, decreasing from 5048 (t = 0.5 nm) to 1032 (t =2 nm). Third, we further investigated the influence of the polarization angle of the incident light on the optical enhancement in the gap region. Finally, the dielectric environment n0 and the refractive index n of the dielectric layer were studied. This work elucidates the unique gap plasmon coupling mechanisms of GNC-based NPOM structures and provides a precise tuning strategy for key structural and optical parameters, endowing the structure with important application prospects in sensing, energy conversion, and photodetection. Full article
(This article belongs to the Section Physics)
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13 pages, 44672 KB  
Article
ARMANI: Dictionary-Learning-Inspired Data-Free Deep Generative Modeling with Meta-Attention and Implicit Preconditioning for Compressively Sampled Magnetic Resonance Imaging
by Ming Wu, Jing Cheng, Qingyong Zhu and Dong Liang
Electronics 2026, 15(7), 1402; https://doi.org/10.3390/electronics15071402 - 27 Mar 2026
Viewed by 403
Abstract
Magnetic resonance imaging (MRI) reconstruction from undersampled k-space data enables accelerated acquisition but leads to a severely ill-posed inverse problem. Although supervised deep learning methods have achieved strong performance, they typically rely on large paired datasets that are difficult to obtain in clinical [...] Read more.
Magnetic resonance imaging (MRI) reconstruction from undersampled k-space data enables accelerated acquisition but leads to a severely ill-posed inverse problem. Although supervised deep learning methods have achieved strong performance, they typically rely on large paired datasets that are difficult to obtain in clinical practice. To address these limitations, we propose a dictionary-learning-inspired dAta-fRee deep generative modeling with Meta-Attention and implicit precoNditIoning for compressively sampled MRI (CS-MRI), termed ARMANI. Specifically, a meta-attention-augmented deep image prior (MA-DIP) generator performs a joint optimization over the latent input η and the network parameter θ, where η is regularized via gradient-domain sparsity and θ is constrained by a ridge penalty, mirroring the adaptive estimation of sparse coefficients and an empirical sparsifying dictionary. Furthermore, we integrate a single-step pseudo-orthogonal projection to achieve implicit preconditioning, which modulates the loss landscape and mitigates ill-conditioning of the forward operator. Experimental results demonstrate that ARMANI consistently outperforms existing SOTA data-free and self-supervised methods, and, with limited training data, achieves performance comparable to or slightly better than the supervised benchmark MoDL, with effective artifact suppression and faithful recovery of fine structural details. Overall, ARMANI shows strong scalability and potential for practical deployment in fully data-free CS-MRI reconstruction scenarios. Full article
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28 pages, 381 KB  
Article
At the Head of the Circle: Women Facilitators and Forms of Authority in Pluralistic Jewish Learning
by Tidhar Gutman and Tanya Zion-Waldoks
Religions 2026, 17(2), 270; https://doi.org/10.3390/rel17020270 - 23 Feb 2026
Viewed by 592
Abstract
This article explores the construction of women’s authority in Israeli pluralistic Batei Midrash (houses of learning). Drawing on qualitative interviews with experienced women facilitators, it examines how they enact a form of authority that differs significantly from traditional models. Beyond deriving legitimacy from [...] Read more.
This article explores the construction of women’s authority in Israeli pluralistic Batei Midrash (houses of learning). Drawing on qualitative interviews with experienced women facilitators, it examines how they enact a form of authority that differs significantly from traditional models. Beyond deriving legitimacy from institutional position or textual mastery, their authority is built through professional vulnerability and relational work. The article develops the concept of Transformative Pedagogical Authority: a stance grounded in ‘power-to’ rather than ‘power-over.’ It argues that facilitators utilize active contraction (Tzimtzum) not as a retreat, but as a deliberate pedagogical strategy to create a ‘hall of Mirrors’, a site of multivocal engagement and interpretive resonance for learners. By analyzing how women navigate questions of legitimacy and authority, the study contributes to broader conversations about gender and pedagogy, offering a model in which authority is reframed not as hierarchical control but as the capacity to enable collective ownership of the knowledge and its production. Full article
14 pages, 4032 KB  
Article
An 850 nm Grating Coupler on Thin-Film Lithium Niobate Enabled by Topological Unidirectional Guided Resonance
by Yuan Fan, Haihua Yu, Hao Yu, Haoran Wang, Yi Zuo and Chao Peng
Photonics 2026, 13(2), 199; https://doi.org/10.3390/photonics13020199 - 17 Feb 2026
Viewed by 1287
Abstract
The inherently high-voltage-length product (VπL) of thin-film lithium niobate (TFLN) modulators in the O-, C-, and L-telecom bands restricts further scaling of photonic integrated circuits’ bandwidth density, driving their migration toward shorter operating wavelengths. Nevertheless, the corresponding grating couplers, [...] Read more.
The inherently high-voltage-length product (VπL) of thin-film lithium niobate (TFLN) modulators in the O-, C-, and L-telecom bands restricts further scaling of photonic integrated circuits’ bandwidth density, driving their migration toward shorter operating wavelengths. Nevertheless, the corresponding grating couplers, as critical optical input/outputs (optical I/Os) interfaces, remain largely undeveloped. Here, we demonstrate an 850 nm TFLN grating coupler designed based on topological unidirectional guided resonance (UGR). By breaking C2 symmetry of the unit cell and precisely tailoring its geometry, we achieve unidirectional upward radiation with a 63.7 dB up/down intensity ratio. Subsequent apodization of groove widths and periods enables precise control of the electrical field distribution in both real and momentum spaces. This yields a vertical-cavity surface-emitting laser (VCSEL)-matched, highly fabrication-tolerant TFLN grating coupler that attains, to the best of our knowledge, the highest simulated coupling efficiency of −0.6 dB without mirrors or hybrid materials. This work delivers a high-efficiency, layout-flexible, and complementary metal oxide semiconductor (CMOS)-compatible optical I/Os solution for short-wavelength TFLN modulators with low VπL. It offers substantial engineering value and broad applicability for on-chip light source integration and high-bandwidth-density short-reach optical interconnects. Full article
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22 pages, 516 KB  
Article
Dynamical Casimir Effect Under the Action of Gravitational Waves
by Gustavo de Oliveira, Thiago Henrique Moreira and Lucas Chibebe Céleri
Entropy 2026, 28(2), 177; https://doi.org/10.3390/e28020177 - 3 Feb 2026
Viewed by 1092
Abstract
Several nontrivial phenomena emerge when a quantum field is subjected to dynamical perturbations, with prominent examples including the Hawking and Unruh effects, as well as the dynamical Casimir effect. In this work, we compute the number of particles produced via the dynamical Casimir [...] Read more.
Several nontrivial phenomena emerge when a quantum field is subjected to dynamical perturbations, with prominent examples including the Hawking and Unruh effects, as well as the dynamical Casimir effect. In this work, we compute the number of particles produced via the dynamical Casimir effect in an ideal cavity, where one of the mirrors is allowed to move under the influence of a gravitational wave. Assuming an oscillatory mirror motion and a plane gravitational wave, we identify the resonance conditions that lead to an exponential increase in the number of created particles through parametric amplification. Full article
(This article belongs to the Special Issue Quantum Nonstationary Systems—Second Edition)
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10 pages, 2670 KB  
Article
Realization of High-Power Single-Frequency Continuous-Wave Tunable 689 nm Laser
by Jiao Wei, Jingru Qiao, Pixian Jin, Jing Su and Huadong Lu
Micromachines 2026, 17(2), 200; https://doi.org/10.3390/mi17020200 - 1 Feb 2026
Viewed by 515
Abstract
By analyzing the influence of the titanium–sapphire (Ti:S) crystal thermal effect on the laser resonator during the generation of a 689 nm laser, the thermal characteristics of the Ti:S crystal operating near the gain edge were investigated in this letter. On this basis, [...] Read more.
By analyzing the influence of the titanium–sapphire (Ti:S) crystal thermal effect on the laser resonator during the generation of a 689 nm laser, the thermal characteristics of the Ti:S crystal operating near the gain edge were investigated in this letter. On this basis, a Ti:S laser with high conversion efficiency suitable for operation at the wavelength of 689 nm was designed. Benefiting from the quantification of thermal effects, the beam waist size at the center of the Ti:S crystal was precisely controlled. Finally, a single-frequency continuous-wave 689 nm laser with an output power of 3.65 W was achieved, and the corresponding optical-to-optical conversion efficiency was up to 23.1%. Then, after locking the transmission peak of the inserted etalon to the resonance frequency of the resonator, the continuous-frequency tuning range of 17 GHz around 689 nm was realized by scanning the voltage applied to the piezoelectric transducer (PZT) mounted on the cavity mirror. Furthermore, based on the realized single-frequency continuous-wave tunable 689 nm laser source, the absorption spectra of strontium atoms near 689 nm were obtained, which established a promising method for preparing 689 nm laser sources designed for strontium atomic ensembles. Full article
(This article belongs to the Special Issue Advanced Optoelectronic Materials/Devices and Their Applications)
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14 pages, 4826 KB  
Article
Quasi-BIC Terahertz Metasurface-Microfluidic Sensor for Organic Compound Detection
by Liang Wang, Kang Chen, Jiahao Niu, Bo Zhang, Qi Lu, Wei Yu, Yanan Xiao, Yi Ni and Chengkun Dong
Photonics 2026, 13(2), 127; https://doi.org/10.3390/photonics13020127 - 29 Jan 2026
Viewed by 1141
Abstract
Bound states in the continuum (BICs) can be transformed into quasi-bound states (quasi-BICs) via intentional symmetry breaking, thereby enabling ultrahigh-Q resonances critical for refractometric sensing applications. To advance detection capabilities for organic analytes, we proposed an all-dielectric metasurface monolithically integrated within a [...] Read more.
Bound states in the continuum (BICs) can be transformed into quasi-bound states (quasi-BICs) via intentional symmetry breaking, thereby enabling ultrahigh-Q resonances critical for refractometric sensing applications. To advance detection capabilities for organic analytes, we proposed an all-dielectric metasurface monolithically integrated within a microfluidic channel. Mirror symmetry was intentionally disrupted through a cylindrical perturbation applied to one of two identical elliptical resonators, which excited a quasi-BIC mode at 1.9591 THz with a numerically validated Q-factor of 1959. This resonance manifested an absorption peak approaching unity, featuring a full-width at half-maximum (FWHM) of merely 1 GHz. Multipolar decomposition revealed that the mode originated from a synergistic electric-quadrupole (EQ)–magnetic-dipole (MD) pair, wherein the EQ contribution exceeded the MD counterpart by 20%. Capitalizing on this high-Q resonance, the sensor attained a sensitivity of 240 GHz per refractive-index unit (GHz RIU−1) and a figure of merit (FOM = S/FWHM) of 240, while demonstrating robust performance against fabrication tolerances spanning −4% to +4%. Additionally, we verified that oblique-incidence illumination could activate a quasi-BIC within the identical spectral band, circumventing the need for structural asymmetry and thus expanding operational versatility. Benefiting from its geometric simplicity and competitive performance, this architecture exhibited substantial potential for on-chip sensing of organic compounds. Full article
(This article belongs to the Special Issue Advances in Optical Sensors and Applications)
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16 pages, 2333 KB  
Article
On-Chip Volume Refractometry and Optical Binding of Nanoplastics Colloids in a Stable Optofluidic Fabry–Pérot Microresonator
by Noha Gaber, Frédéric Marty, Elodie Richalot and Tarik Bourouina
Photonics 2026, 13(1), 91; https://doi.org/10.3390/photonics13010091 - 20 Jan 2026
Viewed by 663
Abstract
Plastic pollution raises concerns for health and the environment. Plastics are not biodegradable but gradually erode to microplastic and nanoplastic particles spreading almost everywhere. Nanoplastics exhibit colloidal behavior. Thereby, their analysis can be accomplished by refractometry, preferably by an on-chip tool. We present [...] Read more.
Plastic pollution raises concerns for health and the environment. Plastics are not biodegradable but gradually erode to microplastic and nanoplastic particles spreading almost everywhere. Nanoplastics exhibit colloidal behavior. Thereby, their analysis can be accomplished by refractometry, preferably by an on-chip tool. We present a study of such colloids using a microfabricated Fabry–Pérot cavity with curved mirrors, which holds a capillary micro-tube used both for fluid handling and light collimation, resulting in an optically stable microresonator. Despite the numerous scatterers within the sample, the sub-millimeter scale cavity provides the advantages of reduced interaction length while maintaining light confinement. This significantly reduces optical loss and hence keeps resonance modes with quality factors (resonant frequency/bandwidth) above 1100. Therefore, small quantities of colloids can be measured by the interference spectral response through the shift in resonant wavelengths. The particles’ Brownian motion potentially causing perturbations in the spectra can be overcome either by post-measurement cross-correlation analysis or by avoiding it entirely by taking the measurements at once by a wideband source and a spectrum analyzer. The effective refractive index of solutions with solid contents down to 0.34% could be determined with good agreement with theoretical predictions. Even lower detection capabilities might be attained by slightly altering the technique to cause particle aggregation achieved solely by light. Full article
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25 pages, 2047 KB  
Review
Advanced Technologies in Extracellular Vesicle Biosensing: Platforms, Standardization, and Clinical Translation
by Seong-Jun Choi, Jaewon Choi, Jin Kim, Si-Hoon Kim, Hyung-Geun Cho, Min-Yeong Lim, Sehyun Chae, Kwang Suk Lim, Suk-Jin Ha and Hyun-Ouk Kim
Molecules 2026, 31(2), 227; https://doi.org/10.3390/molecules31020227 - 9 Jan 2026
Cited by 9 | Viewed by 1692
Abstract
Recently, extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communication that reflect physiological homeostasis and pathological alterations. By encapsulating diverse biomolecules, including proteins, nucleic acids, and lipids, EVs mirror the molecular signatures of their parent cells, thereby positioning EV-based biosensing as [...] Read more.
Recently, extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communication that reflect physiological homeostasis and pathological alterations. By encapsulating diverse biomolecules, including proteins, nucleic acids, and lipids, EVs mirror the molecular signatures of their parent cells, thereby positioning EV-based biosensing as a transformative platform for noninvasive diagnostics, prognostic prediction, and therapeutic monitoring. This review provides a comprehensive overview of the current state and clinical translation of EV biosensing technologies. Herein, we have discussed ongoing efforts toward standardization and analytical validation (e.g., MISEV2023 and EV-TRACK) and evaluated advances in sensing modalities such as surface plasmon resonance (SPR), electrochemical, fluorescence, and magnetic detection systems, which have significantly improved analytical performance in terms of sensitivity and specificity. Furthermore, we highlight recent developments in multiplexed and multiomics integration at the single-EV level and the application of machine learning to enhance diagnostic accuracy and interpret biological heterogeneity. The clinical relevance of EV biosensing has been explored across multiple disease domains, including oncology, neurology, and cardiometabolic and infectious diseases, with an emphasis on translational progress toward standardized, regulatory-compliant, and scalable platforms. Finally, this review identifies key challenges in manufacturing scale-up, quality control, and point-of-care deployment and proposes a unified framework to accelerate the adoption of EV biosensing as a cornerstone of next-generation precision diagnostics and personalized medicine. Full article
(This article belongs to the Special Issue Multifunctional Nanomaterials for Bioapplications, 2nd Edition)
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16 pages, 6655 KB  
Article
Microvibration Suppression for the Survey Camera of CSST
by Renkui Jiang, Wei Liang, Libin Wang, Enhai Liu, Xuerui Liu, Yongchao Zhang, Sixian Le, Zhaoyang Li, Hongyu Wang, Tonglei Jiang, Changqing Lin, Shaohua Guan, Weiqi Xu, Haibing Su, Yanqing Zhang, Junfeng Du and Ang Zhang
Aerospace 2026, 13(1), 65; https://doi.org/10.3390/aerospace13010065 - 8 Jan 2026
Cited by 1 | Viewed by 513
Abstract
The Survey Camera (SC) is the key instrument of the China Space Station Telescope (CSST), with its imaging performance significantly constrained by microvibrations from internal sources such as the shutter and cryocoolers. This paper proposes a systematic microvibration suppression scheme integrating disturbance source [...] Read more.
The Survey Camera (SC) is the key instrument of the China Space Station Telescope (CSST), with its imaging performance significantly constrained by microvibrations from internal sources such as the shutter and cryocoolers. This paper proposes a systematic microvibration suppression scheme integrating disturbance source control, payload isolation, and transfer path optimization to meet the stringent requirements. The Cryocooler Assembly (CCA) compressor adopts a symmetric piston layout and a real-time vibration cancellation algorithm to reduce the vibration. Coupled with a vibration isolator designed by combining hydraulic damping and a flexible structure, it achieves a vibration isolation efficiency of 95%. The shutter adopts dual-blade symmetric design with sinusoidal angular acceleration control, ensuring its vibrations fall within the compensable range of the Fast Steering Mirror (FSM). And the finite element optimization method is used to optimize the dynamic characteristics of the Support Structure (SST) made of M55J carbon fiber composite material, to avoid resonance in the critical frequency bands. System-level tests on the integrated SC show that the RMS values of vibration force and torque within 8–300 Hz are 0.25 N and 0.08 N·m, respectively, meeting design specifications. This scheme validates effective microvibration control, guaranteeing the SC’s high-resolution imaging capability for the CSST mission. Full article
(This article belongs to the Section Astronautics & Space Science)
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