You are currently on the new version of our website. Access the old version .

5 Results Found

  • Article
  • Open Access
38 Citations
7,115 Views
14 Pages

19 May 2016

The lipopolysaccharide binding domain (LBD) in anti-lipopolysaccharide factor (ALF) is the main functional element of ALF, which exhibits antimicrobial activities. Our previous studies show that the peptide LBDv, synthesized based on the modified seq...

  • Article
  • Open Access
27 Citations
8,914 Views
14 Pages

9 August 2016

Anti-lipopolysaccharide factors (ALFs) with a LPS-binding domain (LBD) are considered to have broad spectrum antimicrobial activities and certain antiviral properties in crustaceans. FcALF2 was one isoform of ALFs isolated from the Chinese shrimp Fen...

  • Article
  • Open Access
70 Citations
7,344 Views
15 Pages

27 April 2015

Anti-lipopolysaccharide factor (ALF) is a small protein with broad-spectrum antimicrobial activity, which has potential application in the disease control. Previously, we isolated seven ALF isoforms from the Chinese shrimp Fenneropenaeus chinensis....

  • Article
  • Open Access
11 Citations
4,312 Views
13 Pages

27 April 2018

As a kind of antimicrobial peptides (AMP) in crustacean, anti-lipopolysaccharide factors (ALFs) have broad spectrum antimicrobial activities. In the present study, we identified four ALF genes, EcALF2-5, from the ridgetail prawn Exopalaemon carinicau...

  • Article
  • Open Access
4 Citations
1,838 Views
19 Pages

The Alkaloid Caulerpin Exhibits Potent and Selective Anti-Inflammatory Activity Through Interaction with the Glucocorticoid Receptor

  • Jônatas Sousa Pires dos Santos,
  • Dahara Keyse Carvalho Silva,
  • Vanessa da Silva Oliveira,
  • Sergio Santos Silva Junior,
  • Edivaldo dos Santos Rodrigues,
  • Claudia Valeria Campos de Souza,
  • Sabrina Teixeira Martinez,
  • Osvaldo Andrade Santos-Filho,
  • Cássio Santana Meira and
  • Milena Botelho Pereira Soares

29 May 2025

Inflammation plays a central role in various pathological conditions, necessitating the search for safer and more effective anti-inflammatory agents. This study investigates the anti-inflammatory activity of caulerpin, a bisindolic alkaloid isolated...