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Article

13 Citations

11,387 Views

51 Pages

Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes

Mathieu F. M. Cellier

Biology2013, 2(1), 233-283;https://doi.org/10.3390/biology2010233

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25 January 2013

The Natural resistance-associated macrophage protein 1 (Nramp1 or Solute carrier 11 member 1, Slc11a1) transports divalent metals across the membrane of late endosomes and lysosomes in professional phagocytes. Nramp1 represents an ancient eukaryotic...

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Article

18 Citations

3,657 Views

14 Pages

Melatonin Can Modulate the Effect of Navitoclax (ABT-737) in HL-60 Cells

Alexey Lomovsky,
Yulia Baburina,
Irina Odinokova,
Margarita Kobyakova,
Yana Evstratova,
Linda Sotnikova,
Roman Krestinin and
Olga Krestinina

Antioxidants2020, 9(11), 1143;https://doi.org/10.3390/antiox9111143

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18 November 2020

Melatonin (N-acetyl-5-methoxytryptamine MEL) is an indolamine that has antioxidant, anti-inflammatory and anti-tumor properties. Moreover, MEL is capable of exhibiting both anti-apoptotic and pro-apoptotic effects. In the normal cells, MEL possesses...

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Article

3 Citations

2,193 Views

22 Pages

YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells

Nelida Ines Noguera,
Serena Travaglini,
Stefania Scalea,
Caterina Catalanotto,
Anna Reale,
Michele Zampieri,
Alessandra Zaza,
Maria Rosaria Ricciardi,
Daniela Francesca Angelini and
Agostino Tafuri
+ 3 authors

Cancers2023, 15(15), 4010;https://doi.org/10.3390/cancers15154010

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7 August 2023

In this study we analyzed the expression of Yin and Yang 1 protein (YY1), a member of the noncanonical PcG complexes, in AML patient samples and AML cell lines and the effect of YY1 downregulation on the AML differentiation block. Our results show th...

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