Chimeric antigen receptor (CAR)-T cell therapy is effective in patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) with response rates of 63–84% and complete response observed in 43–54%. Common germline variants...
For the narrow gap dissimilar weld between a ferritic steel and a nickel base superalloy, a nickel base alloy buttering layer is deposited on the ferritic steel side as an intermediate layer. The bonding between the buttering layer and the ferritic s...
CD19 is the most promising target for developing chimeric-antigen receptor (CAR) T cells against B-cell leukemic cancer. Currently, two CAR-T-cell products, Kymriah and Yescarta, are approved for leukemia patients, and various anti-CD19 CAR T cells a...
This paper proposes a recurrent neural network (RNN) model of dead 10 h fuel moisture content (FMC) for real-time forecasting. Weather inputs to the RNN are forecasts from the High-Resolution Rapid Refresh (HRRR), a numerical weather model. Geographi...
FMC63-CAR T cell therapy targeting CD19 protein on malignant B-cells is effective in patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL), with complete response rates of 43–54%. Common germline variants of the immune-...
A fungicide’s ingredients can play a physiological role in crop water-management decisions. Our greenhouse study in 2021 demonstrated that Xyway LFR@FMC at-plant fungicide can significantly improve water-saving potential in corn. In 2022 and 20...
As a technological advantage of ultrasonic non-destructive testing, fully focused imaging can accurately feedback the defective characteristics of the inspected object, greatly improving the detection efficiency. This article aims to address the chal...
P-Glycoprotein (P-gp, also known as MDR1 or ABCB1) is an ATP-binding cassette (ABC) transporter that actively effluxes a wide range of structurally and functionally diverse molecules, playing a crucial role in drug absorption, distribution, and excre...
The existing segmentation-based scene text detection methods mostly need complicated post-processing, and the post-processing operation is separated from the training process, which greatly reduces the detection performance. The previous method, DBNe...
Obesity has been identified as a serious health concern in domestic cats. Feline mammary cancer (FMC) is also a concern, as it is highly prevalent and aggressive. Considering the identified connection between obesity and breast cancer, it is worthwhi...
In this study, an iron-coated montmorillonite composite (FMC) was prepared, and the adsorption and immobilization of cadmium (Cd) was investigated. The composite was coated with spherical amorphous iron (Fe), which can promote the adsorption of Cd. A...
Forest canopy fuel moisture content (FMC) is a critical factor in assessing the vulnerability of a specific area to forest fires. The conventional FMC estimation method, which relies on look-up tables and loss functions, cannot to elucidate the relat...
Improving the accuracy of fire behavior prediction requires better understanding of live fuel, the dominant component of tree crowns, which dictates the consumption and energy release of the crown fire flame-front. Live fuel flammability is not well...
The use of linear methods, for example, the Combined Synthetic Aperture Focusing Technique (C–SAFT), does not allow one to obtain images with high resolution and low noise, especially structural noise in all cases. Non-linear methods should imp...
Bamboo fibers demonstrate enormous potential as the reinforcement phase in composite materials. In this study, in order to find suitable NaOH concentration for bamboo fiber treatment, bamboo fibers were treated with 2 wt.%, 6 wt.% and 10 wt.% NaOH so...
Here, we demonstrate the impact of ferromagnetic layer coating on controlling the magneto-optical response. We found that the transverse magneto-optical Kerr effect (TMOKE) signal and TMOKE hysteresis loops of Ni80Fe20 thin layers coated with a Cr la...
Additive Manufacturing (AM) of parts used in nuclear power plants can solve many issues like those related to obsolescence. Of the gap limiting the use of AM parts in nuclear is the need of reliable non-destructive inspection capable to meet the qual...
Currently, there is a dispute on whether live fuel moisture content (FMC) should be accounted for when predicting a real-world fire-spread rate (RoS). The laboratory and field data results are conflicting: laboratory trials show a significant effect...
Type 2 diabetes (T2D) is a serious health issue with increasing incidences worldwide. However, current medications have limitations due to side effects such as decreased appetite, stomach pain, diarrhea, and extreme tiredness. Here, we report the eff...
Fuel moisture content (FMC) is a crucial variable affecting fuel ignition and rate of fire spread. Much work so far has focused on the usage of remote sensing data from multiple sensors to derive FMC; however, little attention has been devoted to the...
At present, fully mechanized cultivation (FMC) has begun to be utilized in commercial sugarcane production in China. To provide new insights into whether cane yield and health are altered by fully mechanized cultivations, the cane yield and endophyti...
In the last few years MMTV-like nucleotide sequences were detected in some feline and canine mammary tumours. Due to the confirmed role of cats in the epidemiology of the MMTV-like virus, the aim of this study was to investigate the main pathological...
Many academics, urban planners and policymakers subscribe to the benefits of implementing the concept of the 15-Minute City (FMC) in metropolises across the globe. Despite the interest raised by the concept, and other variants of chrono-urbanism, to...
Climate warming is expected to increase fire frequency in many productive obligate seeder forests, where repeated high-intensity fire can initiate stand conversion to alternative states with contrasting structure. These vegetation–fire interactions m...
In medium-sized cities in developing countries, transit services without dedicated lanes have issues related to route compliance, schedules, speed control, and safety. An efficient way for dealing with this issue is the use of Information and Communi...
Feline mammary carcinoma (FMC) is a common aggressive malignancy with a low survival rate that lacks viable therapeutic options beyond mastectomy. Recently, increasing efforts have been made to understand the molecular mechanisms underlying FMC devel...
A creative approach to reducing food waste by reusing industrial cake waste can result in the development of a worldwide favorite snack. This study aimed to evaluate the potential of industrial cake wastes—basic mini cake (BMC), filled mini cak...
Fuel Moisture Content (FMC) is a critical indicator for assessing forest fire risk and formulating early warning strategies, as its spatiotemporal dynamics directly influence the accuracy of fire danger rating. To improve the accuracy of forest FMC e...
Selecting the most suitable machines to use for wood recovery is essential for computing the operating costs of the whole forestry machinery chain (FMC). Nevertheless, a generalized approach for selecting the most suitable FMC and quantifying the cor...
Chronic stress (CS) is known to induce testicular oxidative stress and apoptosis. Fruit of Momordica charantia (FMC) has antioxidant capacity to protect tissue damage, but its effect on sexual activity and testicular damage caused by CS has never bee...
Immigration is being used as a policy lever to sustain the demography of Canadian Francophone minority communities (FMCs). As FMCs become increasingly diverse, concerns have been raised regarding their capacity to develop and sustain a sense of commu...
Emissions and meteorology are significant factors affecting aerosol pollution, but it is not sufficient to understand their relative contributions to aerosol pollution changes. In this study, the observational data and the chemical model (GRAPES_CUAC...
Monitoring the fuel moisture content (FMC) of 10 h dead vegetation is crucial for managing and mitigating the impact of wildland fires. The combination of in situ FMC observations, numerical weather prediction (NWP) models, and satellite retrievals h...
Purpose: To investigate if imaging biomarkers derived from 3-Tesla dual-tracer [(18)F]fluoromethylcholine (FMC) and [68Ga]Ga-PSMAHBED-CC conjugate 11 (PSMA)-positron emission tomography can adequately predict clinically significant prostate cancer (c...
The cellular and molecular basis of choline uptake on PET imaging and MRS-visible choline-containing compounds is not well understood. Choline kinase alpha (ChoKα) is an enzyme that phosphorylates choline, an essential step in membrane synthesi...
Feline mammary carcinoma (FMC) is a highly prevalent tumor, showing aggressive clinicopathological features, with HER2-positive being the most frequent subtype. While, in human breast cancer, the use of anti-HER2 monoclonal antibodies (mAbs) is commo...
Forest fire modeling often requires estimates of fuel moisture status. Among the various fuel variables used for fire modeling studies, the 10-h fuel moisture content (10-h FMC) is a promising predictor since it can be automatically measured in real...
Current flood protection capacities will become inadequate to protect many low-lying coastal cities from climate change-induced flooding in the future. Under climate change uncertainty, an adaptive strategy is required to provide supplemental flood m...
Ultrasonic testing using arrays is becoming widely used to test composite structures in the Aerospace industry. In recent years, the Full Matrix Capture (FMC) technique has been implemented to extract the signals for post-processing to form an image....
This study aimed to assess which multidimensional performance indexes were the best predictors of talent identification in volleyball. Fifty-five female players (age: 13.8 ± 1.81 years; mass: 55.12 ± 8.12 kg; height: 158.23 ± 7.6...
Background: Feline mammary carcinoma (FMC) is a prevalent and fatal carcinoma that predominantly affects unspayed female cats. FMC is the third most common carcinoma in cats but is still underrepresented in research. Current diagnosis methods include...
Several advantages on physiology, productivity, and grape quality have been reported for grapevine treated with seaweed extracts, but little is known about the importance of cyanobacterial-based biostimulants in viticulture. The purpose of this pione...
Feline mammary carcinoma (FMC) is a common neoplasia in cat, being HER2-positive the most prevalent subtype. In woman’s breast cancer, tyrosine kinase inhibitors (TKi) are used as a therapeutic option, by blocking the phosphorylation of the HER2 tyro...
Feline mammary carcinoma (FMC) is the third most common type of neoplasia in cats, sharing similar epidemiological features with human breast cancer. In humans, histone deacetylases (HDACs) play an important role in the regulation of gene expression,...
This study presents the Moisture Dynamic Model (MDM), a new semi-physical formulation designed to estimate Fuel Moisture Content (FMC) using only air temperature and relative humidity. The core innovation of this work lies in the introduction of an A...
Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have s...
Fuel moisture content (FMC) proved to be one of the most relevant parameters for controlling fire behavior and risk, particularly at the wildland-urban interface (WUI). Data relating FMC to spectral indexes for different species are an important requ...
Electronic devices have been used to describe chemical compounds in the food industry. However, there are different models and manufacturers of these devices; thus, there has been little consistency in the type of compounds and methods used for ident...
Chemical resistance of commercial refractory raw materials against Cu slag is critical to consider them as candidates for the production of refractories used in Cu metallurgy. In this study, we show the comparative results for the corrosion resistanc...
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral oncogene homolog (AKT), and the Rapamycin-Insensitive Companion of mTOR (Rictor) expression was investigated by immunohistochemistry in 10 canine mammar...
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