Special Issue "Bioinformatics and Computational Approaches in Viral Genomics and Evolution"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 22188
Interests: virology; virus evolution; RNA viruses; phylogenetics; bioinformatics; pathogen discovery; metagenomics; RNA-seq
Interests: phylodynamics; phylogenetics; infectious disease epidemiology; molecular evolution
Interests: virus evolution; metagenomics; meta-transcriptomics; macroevolution; pathogen discovery; virology
Special Issues, Collections and Topics in MDPI journals
In recent years, bioinformatics and computational methods have become a core component of virus research, underpinning the fields of virus genomics and evolution. The scale and complexity of analyses have grown along with major advances in genetic sequencing and, consequently, have required a paradigm shift with regard to the statistical and computational requirements of viral genomic analysis. For example, in phylogenetics, new methods have been developed to estimate trees with large numbers of taxa (>10,000 sequences) and to infer complex transmission dynamics using machine learning techniques. Similarly, integrative phylodynamic methods can combine key phenotypic “traits” such as sampling location, case counts, and time with virus genetic data to obtain new insights into the epidemic spread of important pathogens such as influenza virus, Zika virus, and HIV. From a macro-evolution perspective, the use of genomic- and metagenomic-based approaches has expanded our knowledge of the diversity and evolutionary history of the entire virosphere, providing new insight into many old questions such as virus origin, genome evolution, evolution time scales, and virus–host interactions.
The purpose of this Special Issue is to bring together a series of articles (both reviews and original research) related the development and application of novel sequencing and analytical approaches to better understand the discovery, transmission, evolution, and molecular epidemiology of viruses across all hosts.
Dr. John-Sebastian Eden
Dr. Sebastián Duchêne
Prof. Dr. Mang Shi
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- computational biology
- virus evolution
- virus genomics
- virus–host interactions