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Open AccessArticle

A Mutation Network Method for Transmission Analysis of Human Influenza H3N2

1
School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou 510006, China
2
Key Laboratory of Tropical Disease Control, Ministry of Education, Sun Yat-sen University, Guangzhou 510006, China
*
Author to whom correspondence should be addressed.
Viruses 2020, 12(10), 1125; https://doi.org/10.3390/v12101125
Received: 1 September 2020 / Revised: 29 September 2020 / Accepted: 1 October 2020 / Published: 3 October 2020
Characterizing the spatial transmission pattern is critical for better surveillance and control of human influenza. Here, we propose a mutation network framework that utilizes network theory to study the transmission of human influenza H3N2. On the basis of the mutation network, the transmission analysis captured the circulation pattern from a global simulation of human influenza H3N2. Furthermore, this method was applied to explore, in detail, the transmission patterns within Europe, the United States, and China, revealing the regional spread of human influenza H3N2. The mutation network framework proposed here could facilitate the understanding, surveillance, and control of other infectious diseases. View Full-Text
Keywords: influenza virus; mutation network; transmission; phylogenetic analysis influenza virus; mutation network; transmission; phylogenetic analysis
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MDPI and ACS Style

Zhang, C.; Wang, Y.; Chen, C.; Long, H.; Bai, J.; Zeng, J.; Cao, Z.; Zhang, B.; Shen, W.; Tang, F.; Liang, S.; Sun, C.; Shu, Y.; Du, X. A Mutation Network Method for Transmission Analysis of Human Influenza H3N2. Viruses 2020, 12, 1125.

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