Recent Progress in Enterovirus Research

Dear Colleagues,

Viruses from the Enterovirus genus of the Picornaviridae family include well known human pathogens such as poliovirus, Coxsackie viruses, rhinoviruses, as well as emerging viruses such as enteroviruses 71 and D68. They are associated with vast spectrum of diseases ranging from common cold, affecting millions of people annually, to relatively rare but devastating myocarditis, type I diabetes and aseptic encephalitis. Global polio eradication campaign initiated by WHO in 1988 with the arsenal of two vaccines, which are still the only vaccines approved against any enterovirus, resulted in dramatic drop of the disease cases worldwide, but fell short of the expectation of complete eradication of poliovirus. Lessons learned during this global effort highlighted the limitations of our knowledge of the virus biology and rekindled the interest in poliovirus and other enterovirus research. Recent advancement in the understanding of molecular biology of enteroviruses, pathogenesis of enteroviral infections, development of novel anti-viral therapeutics and vaccines will be summarized in this special issue of Viruses by the experts in enterovirus research.

Dr. Georgiy Belov
Guest Editor

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