Epidemiology and Prevention of Avian Immunosuppressive Diseases

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Veterinary Vaccines".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2006

Special Issue Editors

Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China
Interests: poultry infectious diseases; vaccine development; immunity; viral receptor; viral pathogenicity
China Animal Health and Epidemiology Center, Qingdao 266032, China
Interests: poultry infectious diseases; epidemiology; vaccine development; diagnostic reagent development; immunity

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Guest Editor
China Institute of Veterinary Drug Control, Beijing 102609, China
Interests: infectious diseases; epidemiology; diagnostic reagent development; immune responses; virus identification

Special Issue Information

Dear Colleagues,

Avian immunosuppressive diseases could damage the immune organs of poultry to a certain extent and significantly reduce their multiple immune functions, leading to vaccination failure, mixed infection, secondary infection, etc., which would bring direct and indirect economic losses to the poultry industry worldwide. At present, an increasing number of poultry diseases have been proved to have immunosuppressive effects; however, the prevention and control methods of avian immunosuppressive diseases still need to be further studied.

This Special Issue aims to focus on the epidemiology and prevention of avian immunosuppressive diseases, including research on epidemiology, virus isolation and identification, vaccine development, and testing methods. Furthermore, our topic will cover various immunosuppressive diseases, including, but not limited to, infectious bursal disease virus (IBDV), avian leukosis virus (ALV), Marek's disease virus (MDV), avian reovirus (ARV), avian influenza virus (AIV), and Newcastle disease virus (NDV). Both original research and review articles are welcome.

Dr. Aijing Liu
Dr. Yang Li
Dr. Tuanjie Wang
Guest Editors

Manuscript Submission Information

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Keywords

  • avian immunosuppressive diseases
  • epidemiology
  • vaccine development
  • animal models
  • immune responses
  • testing methods

Published Papers (1 paper)

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Research

11 pages, 2803 KiB  
Article
Epidemiological Analysis of Avian Reovirus in China and Research on the Immune Protection of Different Genotype Strains from 2019 to 2020
by Dong Liu, Zhong Zou, Shanshan Song, Hongxiang Liu, Xiao Gong, Bin Li, Ping Liu, Qunyi Wang, Fengbo Liu, Dongzu Luan, Xiang Zhang, Yuanzhao Du and Meilin Jin
Vaccines 2023, 11(2), 485; https://doi.org/10.3390/vaccines11020485 - 20 Feb 2023
Cited by 2 | Viewed by 1634
Abstract
Avian reovirus (ARV) is the primary pathogen responsible for viral arthritis. In this study, 2340 samples with suspected viral arthritis were collected from 2019 to 2020 in 16 provinces of China to investigate the prevalence of ARV in China and to characterize the [...] Read more.
Avian reovirus (ARV) is the primary pathogen responsible for viral arthritis. In this study, 2340 samples with suspected viral arthritis were collected from 2019 to 2020 in 16 provinces of China to investigate the prevalence of ARV in China and to characterize the molecular genetic evolution of epidemic strains. From 113 samples analyzed by RT-PCR, 46 strains of avian reovirus were successfully isolated and identified. The genetic evolution of the σC gene showed that 46 strains were distributed in 1–5 branches, with the largest number of strains in branches 1 and 2. The σC gene homology among the strains was low, with approximately 62% homology in branches 4 and 5 and about 55% in the remaining branches. The strains circulating during the ARV epidemic in different provinces were distributed in different branches. The SPF chickens were immunized with inactivated vaccines containing strains from branches 1 and 4 to analyze the cross-immune protection elicited by different branches of ARV strains. A challenge protection test was performed using strains in branches 1, 2, 4, and 5. Our results showed that inactivated vaccines containing strains from branches 1 and 4 could fully protect from strains in branches 1, 4, and 5. The results of this study revealed the genetic diversity among the endemic strains of ARV in China from 2019 to 2020. Each genotype strain elicited partial cross-protection, providing a scientific basis for the prevention and control of ARV. Full article
(This article belongs to the Special Issue Epidemiology and Prevention of Avian Immunosuppressive Diseases)
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