Approaches in Hepatitis Vaccine Design and Vaccination Strategy
A Special Issue of Vaccines (ISSN 2076-393X) belonging to the section "Hepatitis Virus Vaccines".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 683
Editor
Special Issue Information
Dear Colleagues,
Hepatitis B virus (HBV) causes both acute and chronic liver diseases. Chronic HBV infection can lead to severe complications, such as chronic hepatitis, liver failure, and hepatocellular carcinoma. A vaccine for HBV has been available since 1980, despite new infections and HBV-related complications and mortality increasing, particularly in resource-limited countries. Even with the availability of various antiviral drugs to treat chronic hepatitis, these treatments have not proven to be consistently effective over time. Additionally, recent studies suggest that HBV vaccines may offer therapeutic benefits; therefore, there is a need for new strategies to develop more effective treatments and vaccines to control HBV infection.
Therapeutic vaccines, particularly hepatitis B, are in development. They are designed to treat chronic infections by stimulating the body's immune system to clear the virus. While no therapeutic vaccine has yet achieved a functional cure, these vaccines are designed differently from preventative ones, often combining multiple viral antigens and sometimes using novel platforms like mRNA to induce a more potent and specific immune response capable of controlling. There is a need for further development of therapeutic vaccines concerning their composition, antigens, dosages, and methods of administration. This Special Issue will focus on addressing vaccine-related issues to achieve the overarching goal of the "Elimination of Hepatitis" in the near future.
We look forward to receiving your contributions.
Dr. Sheikh Mohammad Fazle Akbar
Guest Editor
Manuscript Submission Information
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Keywords
- hepatitis B virus
- preventive vaccine
- therapeutic vaccine
- nature of vaccines
- route of administration
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