Anatomical, Experimental, and Clinical Studies of Botulinum Neurotoxin in Cosmetic Medicine

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 270

Editor


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Guest Editor
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea
Interests: botulinum neurotoxin; anatomy; clinical anatomy

Special Issue Information

Dear Colleagues,

Botulinum neurotoxin is widely used in cosmetic medicine, and clinical outcomes depend largely on anatomical accuracy during injection. Although the mechanism of action is well established, safety and efficacy are primarily influenced by anatomical structures, tissue planes, and injection depth.

Injection-related risks are closely associated with anatomical variation and diffusion pathways, which also provide a structural basis for understanding potential routes relevant to retrograde transport.

This Special Issue focuses on anatomical, experimental, and clinical studies that emphasize structural analysis, anatomical validation, imaging-guided techniques, and methodology-driven approaches to botulinum neurotoxin application in cosmetic medicine. In this context, anatomical validation may include cadaveric dissection as well as in vivo human studies—such as ultrasonography or clinically designed investigations—to verify injection depth, tissue planes, and neurovascular relationships, thereby improving the safety and reproducibility of clinical techniques.

Dr. Kyu-Lim Lee
Guest Editor

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Keywords

  • botulinum neurotoxin
  • clinical anatomy
  • facial anatomy
  • cosmetic medicine
  • cadaveric study
  • ultrasound-guided injection
  • anatomy-based injection techniques
  • experimental and clinical research

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