Safety of Botulinum Neurotoxins in Temporomandibular Disorders
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 165
Editor
Special Issue Information
Dear Colleagues,
Botulinum neurotoxin is widely used to treat disorders related to muscle hyperactivity. Injected directly into affected muscles, it causes chemical denervation and deep, long-lasting relaxation. In recent years, multidisciplinary groups have actively investigated its use to treat temporomandibular disorders (TMDs). While evidence supports the beneficial effects of botulinum toxin in specific cases of refractory masticatory muscle pain, further studies are critical to establish guidelines and prevent adverse effects. Furthermore, given the wide variety of existing TMD management modalities, the exact role of botulinum neurotoxin compared to alternative therapies requires clarification.
This Special Issue of Toxins aims to evaluate the efficacy, safety and comparative outcomes of botulinum toxin in patients with TMDs. Specifically, the Issue focuses on studies examining the ability of this toxin to reduce pain and improve function relative to other therapeutic procedures. Researchers are invited to contribute original research and reviews to this Issue, advancing global knowledge and clinical practices for temporomandibular disorders.
Dr. Luis Miguel Gonzalez-Perez
Guest Editor
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Keywords
- temporomandibular disorders
- botulinum toxin
- masticatory muscle pain
- orofacial pain
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