Selected Papers from the 7th Iberian Congress on Cyanotoxins / 3rd Ibero-American Congress on Cyanotoxin

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Marine and Freshwater Toxins".

Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 3651

Special Issue Editors


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Guest Editor
1. CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Pólo dos Açores, Universidade dos Açores, 9500-321 Ponta Delgada, Portugal
2. Faculdade de Ciências e Tecnologia, Universidade dos Açores, 9500-321 Ponta Delgada, Portugal
Interests: limnology; phycology; water quality; biodiversity & conservation; phytoplankton; diatoms; paleolimnology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Pólo dos Açores, 9500-321 Ponta Delgada, Portugal
2. Faculdade de Ciências e Tecnologias, Universidade dos Açores, 9500-321 Ponta Delgada, Açores, Portugal
Interests: molecular biology; genetics; biodiversity; cyanobacteria; cyanotoxins; microalgae; phylogeny; blue biotechnology; culture collections
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although cyanobacteria are recognized for their role in forming the aerobic atmosphere that enabled the evolution of superior life forms, they are probably more commonly known for their occurrence in algae blooms associated with the eutrophication of aquatic ecosystems. In the last decades, the synergy between eutrophication and climate change is leading to the rapid increase in cyanobacteria dominance and the frequency of cyanobacterial harmful blooms (cHABs). During their long evolutionary history, cyanobacteria were able to adapt to different habitats and environmental conditions by developing a great morphological and physiological diversity, including the capacity to synthesize a very high number of compounds, both beneficial and harmful.

Cyanotoxins are one of the major health risks associated with water resources. They have toxic effects on humans and animals exposed through drinking water, aquaculture, recreation, and other contamination routes. Most cyanobacteria toxic events are related to microcystins, anatoxins, saxitoxins, and cylindrospermopsin produced by large planktonic species. Still, the production of toxins by planktonic picocyanobacterial and benthic species and the discovery of new toxins highlight the need for more research on this topic.

This Special Issue will gather selected papers presented in the 7th Iberian Congress of Cyanotoxins / 3rd Ibero-American Congress of Cyanotoxins (https://7cic.com/en/home/) with novel research on cyanotoxins, including their monitoring, mitigation and removal, detection methodologies, and biotechnological applications, among other related topics.

Dr. Vitor Gonçalves
Dr. Amélia Fonseca
Guest Editors

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Keywords

  • cyanobacteria
  • cyanotoxins
  • new toxins and detection methods
  • toxicology of cyanobacteria metabolites
  • monitoring, mitigation, and removal of cyanotoxins
  • cHABs under a changing climate
  • biotechnological applications
  • culture collections

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Published Papers (1 paper)

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Research

17 pages, 2036 KiB  
Article
Determination of Multiclass Cyanotoxins in Blue-Green Algae (BGA) Dietary Supplements Using Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry
by María del Mar Aparicio-Muriana, Francisco J. Lara, Monsalud Del Olmo-Iruela and Ana M. García-Campaña
Toxins 2023, 15(2), 127; https://doi.org/10.3390/toxins15020127 - 4 Feb 2023
Cited by 12 | Viewed by 3054
Abstract
In recent years, the consumption of blue-green algae (BGA) dietary supplements is increasing because of their health benefits. However, cyanobacteria can produce cyanotoxins, which present serious health risks. In this work we propose hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry (HILIC-MS/MS) [...] Read more.
In recent years, the consumption of blue-green algae (BGA) dietary supplements is increasing because of their health benefits. However, cyanobacteria can produce cyanotoxins, which present serious health risks. In this work we propose hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry (HILIC-MS/MS) to determine cyanotoxins in BGA dietary supplements. Target toxins, including microcystin-leucine-arginine (MC-LR) and microcystin-arginine-arginine (MC-RR), nodularin, anatoxin-a and three non-protein amino acids, β-N-methylamino-L-alanine (BMAA), 2,4-diaminobutyric acid (DAB) and N-(2-aminoethyl)glycine (AEG), were separated using a SeQuant ZIC-HILIC column. Cyanotoxin extraction was based on solid–liquid extraction (SLE) followed by a tandem-solid phase extraction (SPE) procedure using Strata-X and mixed-mode cation-exchange (MCX) cartridges. The method was validated for BGA dietary supplements obtaining quantification limits from 60 to 300 µg·kg−1. Nine different commercial supplements were analyzed, and DAB, AEG, and MCs were found in some samples, highlighting the relevance of monitoring these substances as precaution measures for the safe consumption of these products. Full article
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