Special Issue "Health Effects Associated with Exposures to Endocrine Disrupting Chemicals"
Deadline for manuscript submissions: closed (31 December 2020).
Interests: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Child Development; Environmental Pollutants; Models, Statistical; Causality; Pharmacoepidemiology; Endocrine Disruptors; Pediatric Obesity; Autism Spectrum Disorder
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Accruing research shows that human exposures to a wide range of endocrine disrupting chemicals (EDCs) could increase the risk of disease across the lifespan by altering the homeostasis or action of endogenous hormones, or other signaling chemicals of the endocrine system. Commonly investigated EDCs include chemicals widely applied in commercial and industrial products, such as per and polyfluoralkyl substances (PFAS), polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), bisphenol A (BPA), phthalates, and certain pesticides. Pharmaceutical agents, including analgesics and painkillers such as acetaminophen, have also been suggested to exhibit strong endocrine disrupting effects. Our understanding of human health risks associated with exposure to EDCs remains limited. The early development period (i.e. in-utero, infancy, and childhood) might be more vulnerable to exposures to EDCs, but depending on the outcomes, relevant exposure windows may include additional periods throughout the entire lifespan.
In this Special Issue, we invite epidemiological research (original articles, reviews, and communications) that addresses human health risks associated with exposures to EDCs. Of interest to this issue are:
- Studies that investigate the associations between exposures to EDCs and human health risks, including but not limited to neurological, reproductive, endocrine, cardiovascular, or immunological outcomes. We encourage studies addressing critical time windows of exposure. In addition to ‘classical’ EDCs, we also encourage studies focusing on less studied chemicals or newer types of compounds that might be classified as EDCs;
- Research addressing biological pathways or mechanisms of EDC exposure and adverse health outcomes, including genomic, epigenomic, metabolomic, and proteomic studies;
- Studies focusing on interacting or mixture effects of two or more types of EDCs. In addition to statistical modeling driven approaches, we encourage biologically driven approaches in which models also consider biological pathways and doses of exposures;
- Studies that characterize sources of exposures in a population-based setting;
- Studies that focus on minority health and health disparities relating to EDC exposures.
Dr. Zeyan Liew
Dr. Gunnar Toft
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- endocrine disrupting chemicals
- adverse health impacts
- critical time windows of exposure
- mixture effects
- sources of exposure
- health disparities