Extraction and Characterization of Phenolic Compounds from Foods and Food Byproducts by Targeted and Untargeted LC-MS Methods

Dear Colleagues,

This Special Issue delves into the cutting-edge advancements in the application of Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) and non-conventional innovative extraction techniques for the recovery and characterization of phenolic compounds. Phenolic compounds, widely distributed in plants, play a pivotal role in various biological activities and are of significant interest in fields ranging from food processing and agri-food side streams to nutrition and medicine.

The collection of articles within this Special Issue spans diverse topics, including innovative extraction techniques, method development for comprehensive phenolic compound analysis/phenolic profiles of the extracts and the elucidation of the biological roles and health implications of these compounds.

The key themes covered in this Special Issue include:

1. Methodological Advances: The Special Issue showcases novel methodologies for extracting phenolic compounds from complex matrices, focusing on optimizing sample preparation techniques and instrument parameters to enhance sensitivity and selectivity.
2. Analytical Techniques: Articles explore the use of LC-MS/MS as a powerful analytical tool, emphasizing its capabilities in separating and detecting phenolic compounds with high precision and accuracy and/or mapping the phenolic fingerprint of the extracts using non-targeted LC-MS methods and multivariate statistical analysis tools. Topics include chromatographic column selection, mass spectrometry parameters, and method validation.
3. Biological Significance: The Special Issue addresses the biological relevance of phenolic compounds, examining their potential therapeutic applications, antioxidant properties, and impact on human health.

Overall, this Special Issue serves as a comprehensive resource for researchers, analysts, and professionals interested in the latest developments and applications of extraction techniques and LC-MS/MS in the characterization of phenolic compounds, fostering a deeper understanding of their significance in diverse fields.'

Dr. Thalia Tsiaka
Prof. Dr. Vassilia J. Sinanoglou
Guest Editors

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