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Special Issue "Proteomes of Extracellular Vesicles"
A special issue of Proteomes (ISSN 2227-7382).
Deadline for manuscript submissions: closed (15 April 2019) | Viewed by 43017
Special Issue Editors
Interests: cancer biomarkers; cellular signaling; clinical proteomics; clinical metabolomics; mass spectrometry imaging; stress response
Interests: clinical cancer immunology; cancer immunotherapy; exosomes as cancer biomarkers; extracellular vesicles; immuno-oncology; immune suppression in cancer; regulatory T cells; tumor-derived exosomes; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Interests: clinical proteomics; extracellular vesicles; immunoproteomics; mass spectrometry; radiobiology; radioproteomics; stress response
Special Issue Information
Most cells release different types of vesicles into the extracellular microenvironment, both in vivo and in vitro, which are known under the general term of “extracellular vesicles (EVs)”. Recently, much attention has been paid to a subset of small EVs called exosomes, because of their role in cell-to-cell communication and involvement in disease-related processes. Exosomes are 30–150nm in size and are membrane-enclosed structures. They are actively secreted by cells via the mechanisms involving multivesicular bodies (MVBs). They transmit complex molecular and genetic information, including signals for cell death, survival, and differentiation, from exosome-secreting cells to multiple types of neighboring or distant recipient cells. The functional role of EVs depends on their molecular cargo, including their proteome content. EVs present in blood and other physiological fluids have a large potential for liquid biopsy and are an emerging source of disease biomarkers. However, the isolation and characterization of EVs, including the analysis of their proteome cargo, remains a challenge and represents an important limitation in this field of research.
We invite you to contribute original research, technical notes, methods papers, and reviews on the subject of the “Proteomes of Extracellular Vesicles”. Papers that cover advances in the methods of isolation and analysis of these vesicles by mass spectrometry approaches as well as their implementation both in basic research and the translational field of disease proteomics will be appreciated by our readership and will be highlighted as important and significant advancements of proteomic science.
Prof. Piotr Widlak
Prof. Theresa L. Whiteside
Prof. Monika Pietrowska
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Proteomes is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cancer cell biology
- extracellular vesicles
- human proteome
- immune cell regulation
- liquid biopsy
- mass spectrometry
- stress response