Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome
AbstractMalignant melanoma is one of the most aggressive types of cancer, and its incidence is increasing rapidly each year. Despite the extensive research into improved diagnostic and treatment methods, early detection and disease constraint still present significant challenges. As successful isolation protocols have been developed, extracellular vesicles (EVs) have become the subject of extensive investigation in terms of their role in cancer progression and as a possible source of disease biomarkers. Besides functional studies, quantitative and qualitative proteomics have recently emerged as promising tools for the advancement of melanoma biomarkers. Nevertheless, the amount of data concerning the proteome of melanoma-derived EVs is still very limited. In this review we cover the current knowledge on protein content of melanoma-derived EVs, with a focus on their potential role in the development and progression of melanomas. View Full-Text
Share & Cite This Article
Surman, M.; Stępień, E.; Przybyło, M. Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome. Proteomes 2019, 7, 21.
Surman M, Stępień E, Przybyło M. Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome. Proteomes. 2019; 7(2):21.Chicago/Turabian Style
Surman, Magdalena; Stępień, Ewa; Przybyło, Małgorzata. 2019. "Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome." Proteomes 7, no. 2: 21.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.