Recent Advances in Bioprocess Engineering and Fermentation Technology
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".
Deadline for manuscript submissions: 10 January 2026 | Viewed by 121
Special Issue Editors
Interests: waste valorisation; biorefineries; fermentation; solid–liquid extraction
Interests: waste management; biological process; anaerobic digestion; circular economy; resource recovery
Interests: organic synthesis focused on solid-phase synthesis of small organic molecules and peptides; development of more sustainable synthetic approaches for biologically active chemical structures; study of selected organic systems; conjugation techniques; and antibody-drug conjugates (ADCs) as delivery systems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioprocess engineering and fermentation technology are evolving rapidly, driven by the integration of artificial intelligence (AI), machine learning (ML), and advanced computational tools in order to address sustainability challenges.
Innovations such as genetic algorithms for process optimisation, metabolic flux analysis, and enhanced anaerobic digestion systems are transforming waste valorisation, bioenergy production, and circular economy frameworks.
Concurrently, advancements in submerged and solid-state fermentation techniques are enabling scalable, resource-efficient biomanufacturing.
This Special Issue highlights pioneering research that bridges computational intelligence, metabolic engineering, and sustainable practices to unlock the potential of agricultural and agro-industrial waste streams.
Suitable topics for this Special Issue include, but are not limited to, the following:
- AI/ML-driven optimisation: genetic algorithms for strain selection, neural networks for predicting fermentation dynamics, and digital twins for real-time bioprocess control.
- Metabolic engineering: in silico flux analysis, CRISPR-enhanced pathways, and multi-omics integration for substrate conversion.
- Anaerobic digestion: novel reactor designs, microbiome engineering, and process intensification for biomethaneand/or biohydrogen
- Sustainable fermentation systems: innovations in solid-state and submerged fermentation for agro-waste valorisation into biofuels, enzymes, or bioplastics.
- Circular biorefineries: hybrid systems combining enzymatic hydrolysis, microbial electrosynthesis, or electro-fermentation for multi-product cascades.
- Waste-to-energy technologies: lifecycle assessments and techno-economic analyses of waste-derived bioenergy systems.
We welcome original research, reviews, and perspectives that address cross-disciplinary synergies, such as AI-guided metabolic modelling, ML-aided anaerobic co-digestion of mixed feedstocks, and policy frameworks for biorefinery scalability.
Contributions must align with global sustainability goals, emphasising carbon neutrality and resource efficiency.
Prof. Dr. José Manuel Pais-Chanfrau
Prof. Dr. Ileana Pereda Reyes
Prof. Dr. Hortensia María Rodríguez Cabrera
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioprocess engineering
- fermentation technology
- machine learning
- genetic algorithms
- metabolic flux analysis
- anaerobic digestion
- biohydrogen
- biomethane
- circular economy
- agro-industrial waste
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