polymers-logo

Journal Browser

Journal Browser

Advances in Biocompatible and Biodegradable Polymers III

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 13340

Special Issue Editors


E-Mail Website
Guest Editor
Technological Institute of Materials (ITM), Universitat Politècnica de València, Plaza Ferrandiz y Carbonell s/n, Alcoy, Alicante, Spain
Interests: biodegradable polymers; recycling; natural additives; biocomposites; polymer compatibilization; polymer rheology;surface modification fillers; thermal and mechanical properties
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Technological Institute of Materials (ITM), Universitat Politècnica de València, Plaza Ferrandiz y Carbonell s/n, Alcoy, Alicante, Spain
Interests: mechanical properties; polymers; composites; surface modification; biodegradable and biocompatible polymers; atmospheric plasma
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Research Institute for Industrial, Radiophysical and Environmental Safety (ISIRYM), Universitat Politècnica de València, Plaza Ferrandiz y Carbonell s/n, Alcoy, Alicante, Spain
Interests: biopolymers; biomass revalorization; PHA and PHB production; chemical recycling; biodegradable polymers; natural additives; polymer rheology; surface modification fillers; polymer membranes
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Among the various strategies to reduce negative environmental impacts due to the uncontrolled consumption and low recovery of conventional plastics, the synthesis of new biodegradable and recyclable plastics is considered one of the most promising. The spectrum of existing biodegradable materials is still very narrow, and so, to achieve greater applicability, mixtures of biodegradable polymers are being investigated using a blending strategy. However, the incompatibilities shown by these mixtures have led to the establishment of several strategies (incorporation of additives, reactive extrusion, copolymerization) to improve this feature. 

This Special Issue of Polymers invites contributions that address advances in the synthesis of new biodegradable polymers, new mixtures of biodegradable polymers and, in particular, compatibility studies, as well as those exploring the influence on their chemical, thermal, mechanical and rheological properties. In addition, we welcome research on the biocompatibility of polymers with the human body, including studies on the degradation of physiological serum, and the influence of their mechanical and thermal properties depending on the time of contact with physiological serum.

Dr. José Miguel Ferri
Dr. Vicent Fombuena Borràs
Prof. Dr. María Fernanda López Pérez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biodegradable polymers
  • biocompatible polymers
  • compatibility
  • blends
  • disintegration
  • polymer miscibility

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Related Special Issue

Published Papers (8 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

19 pages, 5338 KiB  
Article
Exploring the Feasibility of Polysaccharide-Based Mulch Films with Controlled Ammonium and Phosphate Ions Release for Sustainable Agriculture
by Veronica Ciaramitaro, Elena Piacenza, Sara Paliaga, Giuseppe Cavallaro, Luigi Badalucco, Vito Armando Laudicina and Delia Francesca Chillura Martino
Polymers 2024, 16(16), 2298; https://doi.org/10.3390/polym16162298 - 14 Aug 2024
Viewed by 877
Abstract
Bio-based polymers are a promising material with which to tackle the use of disposable and non-degradable plastics in agriculture, such as mulching films. However, their poor mechanical properties and the high cost of biomaterials have hindered their widespread application. Hence, in this study, [...] Read more.
Bio-based polymers are a promising material with which to tackle the use of disposable and non-degradable plastics in agriculture, such as mulching films. However, their poor mechanical properties and the high cost of biomaterials have hindered their widespread application. Hence, in this study, we improved polysaccharide-based films and enriched them with plant nutrients to make them suitable for mulching and fertilizing. Films were produced combining sodium carboxymethyl cellulose (CMC), chitosan (CS), and sodium alginate (SA) at different weight ratios with glycerol and CaCl2 as a plasticizer and crosslinker, respectively, and enriched with ammonium phosphate monobasic (NH4H2PO4). A polysaccharide weight ratio of 1:1 generated a film with a more crosslinked structure and a lower expanded network than that featuring the 17:3 ratio, whereas CaCl2 increased the films’ water resistance, thermal stability, and strength characteristics, slowing the release rates of NH4+ and PO43−. Thus, composition and crosslinking proved crucial to obtaining promising films for soil mulching. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

18 pages, 11234 KiB  
Article
Sustainability in the Development of Natural Pigment-Based Colour Masterbatches and Their Application in Biopolymers
by Ana Ibáñez-García, Raquel Berbegal-Pina, Rosario Vidal and Asunción Martínez-García
Polymers 2024, 16(15), 2116; https://doi.org/10.3390/polym16152116 - 25 Jul 2024
Viewed by 915
Abstract
This article is focused on the development and characterization of a series of biodegradable and eco-friendly colour masterbatches (MBs), based on natural pigments and biodegradable polylactic acid (PLA) and polybutylene succinate (PBS). Four commercial natural pigments were used, spirulina, curcumin, beetroot and chlorophyllin, [...] Read more.
This article is focused on the development and characterization of a series of biodegradable and eco-friendly colour masterbatches (MBs), based on natural pigments and biodegradable polylactic acid (PLA) and polybutylene succinate (PBS). Four commercial natural pigments were used, spirulina, curcumin, beetroot and chlorophyllin, to develop the colour masterbatches using a twin-screw extruder. The natural pigment-based MBs were added at 2, 4 and 6 wt%, as additives to study the effect on the properties of injected biodegradable parts (PLA and PBS). The injected samples were characterized in terms of their mechanical (tensile and Charpy impact tests) and visual properties (according to CieLab). In addition, the ageing of the coloured material was followed by colorimetric analysis after its exposure under a Xenon lamp. The mechanical results showed that the addition of coloured masterbatches in different percentages (2–6 wt%) did not significantly change the properties of the materials with respect to the as-received ones. A noticeable colour difference in the injected samples was observed after the first 50 h of artificial light exposure. Regarding environmental concerns, the study showed that the carbon footprint of natural pigments and electricity consumption during extrusion and pelletizing were lower. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

20 pages, 9510 KiB  
Article
Computational Analysis of Polymeric Biodegradable and Customizable Airway Stent Designs
by Ada Ayechu-Abendaño, Aurora Pérez-Jiménez, Carmen Sánchez-Matás, José Luis López-Villalobos, Cristina Díaz-Jiménez, Rocío Fernández-Parra and Mauro Malvè
Polymers 2024, 16(12), 1691; https://doi.org/10.3390/polym16121691 - 14 Jun 2024
Viewed by 1235
Abstract
The placement of endotracheal prostheses is a procedure used to treat tracheal lesions when no other surgical options are available. Unfortunately, this technique remains controversial. Both silicon and metallic stents are used with unpredictable success rates, as they have advantages but also disadvantages. [...] Read more.
The placement of endotracheal prostheses is a procedure used to treat tracheal lesions when no other surgical options are available. Unfortunately, this technique remains controversial. Both silicon and metallic stents are used with unpredictable success rates, as they have advantages but also disadvantages. Typical side effects include restenosis due to epithelial hyperplasia, obstruction and granuloma formation. Repeat interventions are often required. Biodegradable stents are promising in the field of cardiovascular biomechanics but are not yet approved for use in the respiratory system. The aim of the present study is to summarize important information and to evaluate the role of different geometrical features for the fabrication of a new tracheo-bronchial prosthesis prototype, which should be biodegradable, adaptable to the patient’s lesion and producible by 3D printing. A parametric design and subsequent computational analysis using the finite element method is carried out. Two different stent designs are parameterized and analyzed. The biodegradable material chosen for simulations is polylactic acid. Experimental tests are conducted for assessing its mechanical properties. The role of the key design parameters on the radial force of the biodegradable prosthesis is investigated. The computational results allow us to elucidate the role of the pitch angle, the wire thickness and the number of cells or units, among other parameters, on the radial force. This work may be useful for the design of ad hoc airway stents according to the patient and type of lesion. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

16 pages, 6760 KiB  
Article
Enhanced Crystallization of Sustainable Polylactic Acid Composites Incorporating Recycled Industrial Cement
by Yong-Min Lee, Kwan-Woo Kim, Jae-Yeon Yang and Byung-Joo Kim
Polymers 2024, 16(12), 1666; https://doi.org/10.3390/polym16121666 - 12 Jun 2024
Viewed by 861
Abstract
Globally, the demand for single-use plastics has increased due to the rising demand for food delivery and household goods. This has led to environmental challenges caused by indiscriminate dumping and disposal. To address this issue, non-degradable plastics are being replaced with biodegradable alternatives. [...] Read more.
Globally, the demand for single-use plastics has increased due to the rising demand for food delivery and household goods. This has led to environmental challenges caused by indiscriminate dumping and disposal. To address this issue, non-degradable plastics are being replaced with biodegradable alternatives. Polylactic acid (PLA) is a type of biodegradable plastic that has excellent mechanical properties. However, its applications are limited due to its low crystallinity and brittleness. Studies have been conducted to combat these limitations using carbon or inorganic nucleating agents. In this study, waste cement and PLA were mixed to investigate the effect of the hybrid inorganic nucleating agent on the crystallinity and mechanical properties of PLA. Waste cement accelerated the lamellar growth of PLA and improved its crystallinity. The results indicate that the flexural and impact strengths increased by approximately 3.63% and 76.18%, respectively. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

18 pages, 7744 KiB  
Article
Preparation and Preliminary Analysis of Several Nanoformulations Based on Plant Extracts and Biodegradable Polymers as a Possible Application for Chronic Venous Disease Therapy
by Andreea Roxana Ungureanu, Emma Adriana Ozon, Adina Magdalena Musuc, Mihai Anastasescu, Irina Atkinson, Raul-Augustin Mitran, Adriana Rusu, Liliana Popescu and Cerasela Elena Gîrd
Polymers 2024, 16(10), 1362; https://doi.org/10.3390/polym16101362 - 10 May 2024
Viewed by 1391
Abstract
Nanotechnology is one of the newest directions for plant-based therapies. Chronic venous disease often predisposes to long-term and invasive treatment. This research focused on the inclusion of vegetal extracts from Sophorae flos (SE), Calendulae flos (CE), and Ginkgo bilobae folium (GE) in formulations [...] Read more.
Nanotechnology is one of the newest directions for plant-based therapies. Chronic venous disease often predisposes to long-term and invasive treatment. This research focused on the inclusion of vegetal extracts from Sophorae flos (SE), Calendulae flos (CE), and Ginkgo bilobae folium (GE) in formulations with PHB and PLGA polymers and their physicochemical characterization as a preliminary stage for possible use in the development of a complex therapeutic product. The samples were prepared by an oil–water emulsification and solvent evaporation technique, resulting in suspensions with high spreadability and a pH of 5.5. ATR-FTIR analysis revealed bands for stretching vibrations (O-H, C=O, and C-H in symmetric and asymmetric methyl and methylene) in the same regions as the base components, but switched to high or low wavenumbers and absorbance, highlighting the formation of adducts/complexes between the extracts and polymers. The obtained formulations were in the amorphous phase, as confirmed by XRD analysis. AFM analysis emphasized the morphological peculiarities of the extract–polymer nanoformulations. It could be noticed that, in the case of SE-based formulations, the dominant characteristics for SE-PHB and SE-PLGA composition were the formation of random large (SE-PHB) and smaller uniform (SE-PLGA) particles; further on, these particles tended to aggregate in the case of SE-PHB-PLGA. For the CE- and GE-based formulations, the dominant surface morphology was their porosity, generally with small pores, but larger cavities were observed in some cases (CE- and GE-PHB). The highest roughness values at the (8 µm × 8 μm) scale were found for the following samples and succession: CE-PHB < SE-PLGA < SE-PHB-PLGA. In addition, by thermogravimetric analysis, impregnation in the matrix of compression stockings was evaluated, which varied in the following order: CE-polymer > SE-polymer > GE-polymer. In conclusion, nine vegetal extract–polymer nanoformulations were prepared and preliminarily characterized (by advanced physicochemical methods) as a starting point for further optimization, stability studies, and possible use in complex pharmaceutical products. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

15 pages, 3796 KiB  
Article
Magnetic Resonance-Based Analytical Tools to Study Polyvinylpyrrolidone–Hydroxyapatite Composites
by Alina Petrova, Georgy Mamin, Oleg Gnezdilov, Inna Fadeeva, Olga Antonova, Anna Forysenkova, Iulian V. Antoniac, Julietta V. Rau and Marat Gafurov
Polymers 2023, 15(22), 4445; https://doi.org/10.3390/polym15224445 - 17 Nov 2023
Viewed by 1988
Abstract
The synthesis of biocompatible and bioresorbable composite materials, such as a “polymer matrix-mineral constituent,” stimulating the natural growth of living tissues and the restoration of damaged parts of the body, is one of the challenging problems in regenerative medicine and materials science. Composite [...] Read more.
The synthesis of biocompatible and bioresorbable composite materials, such as a “polymer matrix-mineral constituent,” stimulating the natural growth of living tissues and the restoration of damaged parts of the body, is one of the challenging problems in regenerative medicine and materials science. Composite films of bioresorbable polymer of polyvinylpyrrolidone (PVP) and hydroxyapatite (HA) were obtained. HA was synthesized in situ in the polymer solution. We applied electron paramagnetic resonance (EPR) and nuclear magnetic resonance (NMR) approaches to study the composite films’ properties. The application of EPR in two frequency ranges allowed us to derive spectroscopic parameters of the nitrogen-based light and radiation-induced paramagnetic centers in HA, PVP and PVP-HA with high accuracy. It was shown that PVP did not significantly affect the EPR spectral and relaxation parameters of the radiation-induced paramagnetic centers in HA, while light-induced centers were detected only in PVP. Magic angle spinning (MAS) 1H NMR showed the presence of two signals at 4.7 ppm and −2.15 ppm, attributed to “free” water and hydroxyl groups, while the single line was attributed to 31P. NMR relaxation measurements for 1H and 31P showed that the relaxation decays were multicomponent processes that can be described by three components of the transverse relaxation times. The obtained results demonstrated that the applied magnetic resonance methods can be used for the quality control of PVP-HA composites and, potentially, for the development of analytical tools to follow the processes of sample treatment, resorption, and degradation. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

16 pages, 10379 KiB  
Article
Green, Eco-Friendly, Highly Biocompatible and Bioactive Nanocomposite-Based Biopolymers Loaded with ZnO@Fe3O4 Nanoparticles
by Ayed S. Allogmani, Roushdy M. Mohamed and Mohamed S. Hasanin
Polymers 2023, 15(17), 3641; https://doi.org/10.3390/polym15173641 - 4 Sep 2023
Cited by 6 | Viewed by 1491
Abstract
Biocompatibility is a major concern for promising multifunctional bioactive materials. Unfortunately, bioactive materials lack biocompatibility in some respects, so active ingredient formulations are urgently needed. Bimetallic nanoparticles have demonstrated drawbacks in stabilized biocompatible formulations. This study examined the preparation of biomaterial-based multifunctional biopolymers [...] Read more.
Biocompatibility is a major concern for promising multifunctional bioactive materials. Unfortunately, bioactive materials lack biocompatibility in some respects, so active ingredient formulations are urgently needed. Bimetallic nanoparticles have demonstrated drawbacks in stabilized biocompatible formulations. This study examined the preparation of biomaterial-based multifunctional biopolymers via an eco-friendly formulation method using ultrasound. Bimetallic zinc oxide/iron oxide (magnetic form) nanoparticles (ZnO@Fe3O4NPs) were formulated using casein and starch as capping agents and stabilizers. The formulated nanocomposite was characterized using ultraviolet–visible spectroscopy (UV-vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), scanning electron microscopy (SEM), and high-resolution transmission electron microscopy (HR-TEM). Herein, the formulated nanocomposite was shown to have a thermally stable nanostructure, and the bimetallic ZnO@Fe3O4 NPs were measured as 85 nm length and 13 nm width. Additionally, the biocompatibility test showed its excellent cytocompatibility with Wi 38 and Vero normal cell lines, with IC50 550 and 650 mg/mL, respectively. Moreover, the antimicrobial activity was noted against six pathogens that are represent to the most common pathogenic microbes, with the time required for killing of bacteria and unicellular fungi being 19 h and 61 h for filamentous fungi with remarket an excellent antioxidant activity. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

Review

Jump to: Research

18 pages, 2300 KiB  
Review
Recent Approaches to the Plasticization of Poly(lactic Acid) (PLA) (A Review)
by Elena E. Mastalygina and Kristine V. Aleksanyan
Polymers 2024, 16(1), 87; https://doi.org/10.3390/polym16010087 - 27 Dec 2023
Cited by 10 | Viewed by 3594
Abstract
Poly(lactic acid) (PLA) is a polyester attracting growing interest every year in different application fields, such as packaging, cosmetics, food, medicine, etc. Despite its significant advantages, it has low elasticity that may hinder further development and a corresponding rise in volume of consumption. [...] Read more.
Poly(lactic acid) (PLA) is a polyester attracting growing interest every year in different application fields, such as packaging, cosmetics, food, medicine, etc. Despite its significant advantages, it has low elasticity that may hinder further development and a corresponding rise in volume of consumption. This review opens a discussion of basic approaches to PLA plasticization. These considerations include copolymerization and blending with flexible polymers, introducing oligomers and low-molecular additives, as well as structural modification. It was demonstrated that each approach has its advantages, such as simplicity and low cost, but with disadvantages, including complex processing and the need for additional reagents. According to the analysis of different approaches, it was concluded that the optimal option is the application of copolymers as the additives obtained via reactive mixing to PLA and its blends with other polymers. Full article
(This article belongs to the Special Issue Advances in Biocompatible and Biodegradable Polymers III)
Show Figures

Figure 1

Back to TopTop