Nanotechnological Advances in Plant Essential Oils

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 4499

Special Issue Editors


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Guest Editor
INQUISUR, Departamento de Química, Universidad Nacional del Sur (UNS)-CONICET, Bahia Blanca B8000CPB, Argentina
Interests: natural product chemistry; bioactive compounds; synthesis of natural product derivatives; essential oils, bioinsecticides; cholinesterase inhibitors
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Guest Editor
INBIOSUR, Departmento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS) – CONICET, Bahia Blanca B8000CPB, Argentina
Interests: essential oils nanoformulation; stored-products insect pest; active packaging; bioinsecticides
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Essential oils (EOs) obtained from plants have several and important applications in the pharmaceutical, food, cosmetic and agricultural industries. These oils are complex mixtures of natural products produced by plants of medicinal or nutritional importance, with variable yields depending on the extraction methods. The chemical composition of EOs is diverse and characteristic of each plant species. Plants EOs are appreciated for their aroma and flavor, as well as for the important biological activities that they display such as antibacterial, antioxidant, antifungal, antiparasitic, antiviral, enzyme inhibition and insecticide, among others.

Despite their valuable biological properties, the commercial use of EOs is delayed because of their low water solubility, high volatility, thermal decomposition, high oxidation rates and in many cases, poor extraction yields. To overcome these problems and enhance EO efficacy, several nanotechnological advances have been reported over the past decades. Searching for more environmentally friendly extraction methods, innovative and alternative techniques are currently available to improve the recovery of these natural products, such as emergent and ecofriendly pretreatments or alternative faster and cheaper extractions methods. Additionally, the incorporation of these volatile and complex mixtures of secondary metabolites into nanoscale materials and nanodevices has proven to be a successful strategy to protect EOs from degradation and losses by evaporation, achieving a controlled release of EOs and facilitating their handling.

This Special Issue aims to provide a general overview on the latest advances in nanotechnological solutions that might help to fully exploit the rich chemical diversity and biological applications of the valuable EOs produced by plants. Original research articles and specialized critical reviews dealing with these advances are welcome.

Dr. Ana Paula Murray
Dr. Jorge Omar Werdin Gonzalez
Guest Editors

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Keywords

  • essential oils
  • nanotechnology
  • nanoformulation
  • nanoparticles
  • nanoemulsions
  • biological activity
  • ecofriendly extraction techniques
  • pretreatments

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Published Papers (1 paper)

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Research

15 pages, 2439 KiB  
Article
Antioxidant, Antibacterial, and Anticancer Activity of Ultrasonic Nanoemulsion of Cinnamomum Cassia L. Essential Oil
by Aftab Alam, Mohammad Javed Ansari, Mohammed H. Alqarni, Mohammad Ayman Salkini and Mohammad Raish
Plants 2023, 12(4), 834; https://doi.org/10.3390/plants12040834 - 13 Feb 2023
Cited by 24 | Viewed by 4084
Abstract
Cinnamomum cassia (C. assia) has long been used in traditional holistic medicine for its medicinal properties. It is used as an antioxidant, antibacterial, anti-inflammatory and anticancer agent. Cinnamon, in particular, the essential oil of C. cassia, has significant biological properties. [...] Read more.
Cinnamomum cassia (C. assia) has long been used in traditional holistic medicine for its medicinal properties. It is used as an antioxidant, antibacterial, anti-inflammatory and anticancer agent. Cinnamon, in particular, the essential oil of C. cassia, has significant biological properties. Despite this, the volatility, stability, and insolubility of C. cassia essential oil (CEO) remain the main disadvantages that limit its application, ultimately affecting its pharmacological efficacy. To find a solution to this problem, we developed the CEO nanoemulsion (CEO-NE). For lipophilic compounds, insoluble nanoemulsion-based formulations are a popular delivery strategy. In this research work, a highly stable dosage form named CEO-NE was successfully developed using polysorbate 80 and water. The findings show that the synthesized CEO has a uniform shape with a PDI of 0.380 and an adequate particle size of 221.8 nm. The antioxidant outcomes show excellent results for CEO-NE compared to CEO against DPPH and hydrogen peroxide. The obtained antibacterial activity of CEO-NE was more efficient than that of CEO against Klebsiella pneumonia (MTCC 8911) with 0.025% and 0.05%, respectively. The CEO-NE preparation was tested against an alveolar lung adenocarcinoma cell line (A549) with an IC50 of 50.21 µg/mL for CEO and 18.05 µg/mL for CEO-NE, respectively. These results are encouraging for future translational studies on CEO-NE use in lung cancer therapy due to its excellent antioxidant, antibacterial, and killing kinetic properties. Full article
(This article belongs to the Special Issue Nanotechnological Advances in Plant Essential Oils)
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