Green Chemistry of Natural Products in Plants: Extraction Methodologies and Alternative Solvents

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 2056

Special Issue Editor


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Guest Editor
Department of Chemistry, Faculty of Sciences, University of Chile, Las Palmeras 3425, Nuñoa, Santiago 7800024, Chile
Interests: conventional and non-conventional extraction; isolation of secondary metabolites from terrestrial and marine organisms; nuclear magnetic resonance (NMR); liquid chromatography/mass spectrometry (LC/MS/MS); green chemistry from natural products
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Special Issue Information

Dear Colleagues,

Solvents are used in chemical processes to facilitate separations and purifications. They are often volatile organic compounds and are considered a major environmental concern that can cause health problems. Therefore, renewable and biodegradable solvents should be developed and implemented in natural product chemistry. Green technology can minimize or eliminate the use of toxic solvents, which are known as cold extraction techniques. Among green technologies for the extraction of natural products, there is supercritical fluid, pressurized liquid, ultrasound, microwave, pulsed electric field, high hydrostatic pressure, and high voltage electrical discharges.

This Special Issue, “Green Chemistry of Natural Products in Plants: Extraction Methodologies and Alternative Solvents”, aims to publish original contributions on this topic. Research articles as well as reviews on how alternative solvents and/or green technologies contribute to the development of natural product chemistry are welcome.

Dr. Carlos Areche
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • alternative solvents
  • extraction
  • green chemistry
  • unconventional extraction
  • green technology
  • natural products
  • plants
  • ultrasound
  • microwave
  • supercritical fluids

Published Papers (1 paper)

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Research

16 pages, 6126 KiB  
Article
Antioxidant and Antimicrobial Properties and GC-MS Chemical Compositions of Makwaen Pepper (Zanthoxylum myriacanthum) Extracted Using Supercritical Carbon Dioxide
by Sudarut Nadon, Noppol Leksawasdi, Kittisak Jantanasakulwong, Pornchai Rachtanapun, Warintorn Ruksiriwanich, Sarana Rose Sommano, Amin Mousavi Khaneghah, Juan M. Castagnini, Francisco J. Barba and Yuthana Phimolsiripol
Plants 2023, 12(11), 2211; https://doi.org/10.3390/plants12112211 - 3 Jun 2023
Cited by 2 | Viewed by 1706
Abstract
This research aimed to optimize pressure (10–20 MPa) and temperature (45–60 °C) conditions for supercritical fluid extraction (SFE) of Makwaen pepper (Zanthoxylum myriacanthum) extract (ME) in comparison to conventional hydro-distillation extraction. Various quality parameters, including yield, total phenolic compounds, antioxidants, and [...] Read more.
This research aimed to optimize pressure (10–20 MPa) and temperature (45–60 °C) conditions for supercritical fluid extraction (SFE) of Makwaen pepper (Zanthoxylum myriacanthum) extract (ME) in comparison to conventional hydro-distillation extraction. Various quality parameters, including yield, total phenolic compounds, antioxidants, and antimicrobial activities of the extracts, were assessed and optimized using a central composite design. The optimal SFE conditions were found to be 20 MPa at 60 °C, which resulted in the highest yield (19%) and a total phenolic compound content of 31.54 mg GAE/mL extract. IC50 values for DPPH and ABTS assays were determined to be 26.06 and 19.90 μg/mL extract, respectively. Overall, the ME obtained through SFE exhibited significantly better physicochemical and antioxidant properties compared to ME obtained through hydro-distillation extraction. Gas chromatography-mass spectrometry (GC-MS) analysis revealed that beta-pinene was the major component in the ME obtained through SFE (23.10%), followed by d-limonene, alpha-pinene, and terpinen-4-ol at concentrations of 16.08, 7.47, and 6.34%, respectively. On the other hand, the hydro-distillation-extracted ME showed stronger antimicrobial properties than the SFE-extracted ME. These findings suggest that both SFE and hydro-distillation have the potential for extracting Makwaen pepper, depending on the intended purpose of use. Full article
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