Innovative Health-Promoting Applications of Byproducts from Agricultural Production

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 1601

Special Issue Editors


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Guest Editor

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Guest Editor
Department of Pharmacy, University “G.d’Annunzio” of Chieti-Pescara, 66100 Chieti, Italy
Interests: botanical and phytochemical characterization of medicinal plants and agricultural by-products
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit original articles to this Special Issue entitled “Innovative Health-Promoting Applications of Byproducts from Agricultural Production (Edition 2023)”.

This Special Issue (SI) aims to highlight all aspects related to the preparation, extraction and phytochemical and morphological investigations of plant material derived from high-quality waste byproducts of medicinal, aromatic, and food plants. The aim of the present SI is focused on the new worldwide research interest in the valorization of productive chains that are improvable in terms of sustainability. This SI will consider studies that are related to this aspect from multiple points of view, namely, extract optimization, with particular regard for biocompatible solvents and processes and comparative studies of extraction techniques.

Manuscripts describing at least one of the following items are welcome:

-Description of plant materials and crude extracts: morphological analysis, parameters of the extraction, quantitative analysis of secondary metabolites (qualitative analyses are accepted only if they refer to untargeted metabolomics analysis, witnessed by HPLC-MS data);

-Pharma-toxicological investigations performed at multiple levels: in vitro, ex vivo, and in vivo studies);

-Innovative approach-based component–target analysis and alternative pharma-toxicological methods are encouraged, as well.

The present Special Issue is also part of the third mission activities of the “Giardino dei Semplici” botanical garden, which is operated by the “G. d’Annunzio” University within the Department of Pharmacy as the elective place where academic innovation meets the reality of productive chains.

As a concluding remark, all contributors are invited to highlight the connection between their research and selected targets among the 17 SDGs of the Agenda 2030.

Dr. Claudio Ferrante
Prof. Dr. Luigi Menghini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant material
  • by-products
  • herbal extracts
  • metabolomics
  • secondary metabolites
  • circular economy
  • production chain
  • biological effects

Published Papers (1 paper)

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Research

17 pages, 3368 KiB  
Article
Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica
by Alessandra Acquaviva, Simonetta Cristina Di Simone, Nilofar, Abdelhakim Bouyahya, Gokhan Zengin, Lucia Recinella, Sheila Leone, Luigi Brunetti, Abdullahi Ibrahim Uba, Osman Guler, Maruf Balos, Ugur Cakilcioğlu, Luigi Menghini, Claudio Ferrante, Giustino Orlando, Maria Loreta Libero and Annalisa Chiavaroli
Plants 2023, 12(15), 2785; https://doi.org/10.3390/plants12152785 - 27 Jul 2023
Cited by 6 | Viewed by 1282
Abstract
Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. Nepeta italica is a medicinal plant traditionally used for its analgesic effects, and in the present study, the phytochemical composition [...] Read more.
Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. Nepeta italica is a medicinal plant traditionally used for its analgesic effects, and in the present study, the phytochemical composition and biological effects of hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol, ethanol-water, and water extracts of the aerial parts were investigated for determining phenolic composition, antioxidant effects, and anti-inflammatory effects in isolated mouse colon specimens exposed to lipopolysaccharide (LPS). Polar extracts were the richest in terms of phenolic compounds, especially rosmarinic acid. In parallel, ethanol, ethanol-water, and water extracts were also the most effective as scavenging/reducing and enzyme inhibition agents, especially towards cholinesterases and α-glucosidase, and in inhibiting the LPS-induced cyclooxygenase-2 (COX-2) and tumor necrosis factor α (TNFα) gene expression in mouse colon. This poses the basis for future in vivo investigations for confirming the protective effects of polar extracts of N. italica against inflammatory bowel diseases. Full article
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