Nanoparticles for Targeting and Treating Macrophages
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 21682
Special Issue Editor
2. August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain
3. Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA
Interests: nanoparticles; macrophages; liver; regeneration; fibrosis; inflammation
Special Issue Information
Dear Colleagues,
Nanoparticles are nanomaterials with three external nanoscale dimensions with tunable physical, chemical, and biological characteristics. Regardless of the nanomaterial composition, macrophages can detect and incorporate these foreign bodies by phagocytosis. Recent investigations are taking advantage of this biological fact to design nanoparticles for specific macrophage targeting and treatment in a wide array of diseases. Macrophages are plastic cells from the innate immune system that play different roles in the development, homeostasis, tissue repair and immune response. Indeed, macrophage modulation is of vital importance in chronic inflammation, fibrosis, wound healing, and cancer. Nanoparticles can be modified by the addition of ligands to achieve specific macrophage targeting for drug or gene therapy. They can also be integrated in hydrogels or medical devices to attract and modulate macrophages and the innate immune response. The aim of this issue is to uncover all the different strategies to use nanoparticles to target and modulate macrophages.
As the Guest Editor of the Pharmaceutics Special Issue entitled “Nanoparticles for Targeting and Treating Macrophages”, I would like to cordially invite you to contribute with a research article or a review paper to this Issue due to your excellent contributions to this field. This Special Issue aims to uncover all the different strategies to use nanoparticles to target and treat macrophages.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following: Nanoscale colloidal systems, nanomaterials, hydrogels, or devices incorporating nanoparticles designed to target and treat macrophages.
I look forward to receiving your contributions.
Dr. Pedro Melgar-Lesmes
Guest Editor
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Keywords
- nanoparticles
- macrophages
- targeting
- inflammation
- fibrosis
- wound healing
- regeneration
- hydrogels
- cancer
- devices
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