Peptide-Based Drug Delivery Systems: From Design to Application

Dear Colleagues,

Drug delivery systems play a crucial role in many cases to get a very efficient drug conjugate. There are several types of these systems, such as peptides, polypeptides, lipids, and nanoparticles. Unfortunately there is not a “magic” solution for the delivery of any kind of drug molecules. For developing the best compound, the optimization of the delivery unit and the construction of the compound should be necessary. Among the delivery system peptides, the base ones are very promising. These molecules can be synthesized and modified in a fast process. The fine-tuning of their properties can be extended by using non-natural amino acid substitutions. Besides drug delivery, they are able to target tissues or specific cells.

This Special Issue aims to emphasize and to highlight the design and applicability of peptide-based drug delivery systems. Original research papers and reviews are welcomed about newly developed peptide-based drug delivery systems, conjugates of these delivery units, structure–activity relationships, and the effect of different chemical modifications. We encourage the publication of comprehensive studies about the influence of the composition of conjugates (e.g., spacer, linker, and the position and order of the parts of the conjugates) and the effect of chemical modifications (e.g., the chemistry of conjugation and amino acid substitutions).  

Dr. Zoltán Bánóczi
Prof. Dr. Gábor Mező
Guest Editors

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