Nano-Based Technology for Glioblastoma
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 1814
Special Issue Editors
2. ALiCE—Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal
Interests: drug delivery; targeted therapy; brain delivery; brain cancer; glioblastoma; cancer therapy; neurodegenerative disease therapy; biophysical models; drug–membrane interactions
Special Issues, Collections and Topics in MDPI journals
2. LEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal
Interests: brain cancer; gliomagenesis; organoids; targeted therapy
Special Issue Information
Dear Colleagues,
Nano-based technology offers promising avenues for treating glioblastoma, the most common and deadliest form of primary brain cancer in adults. Innovative approaches utilizing nanoparticles to deliver therapeutic agents directly to tumor cells have been successfully designed to enhance drug efficacy while minimizing off-target effects. Nanoparticles can not only penetrate the blood–brain barrier, allowing for targeted drug delivery to tumor cells, but can also be engineered to release drugs in response to specific stimuli within the tumor microenvironment. The goal of these platforms is to reduce systemic toxicity, while also enabling combination therapies, by delivering multiple drugs simultaneously to avoid drug resistance and improve treatment efficacy. Overall, nano-based technology holds immense potential for revolutionizing glioblastoma therapy, offering hope for improved patient outcomes and survival rates.
Under this scope, we are pleased to invite you to participate in the Special Issue of Pharmaceutics, entitled “Nano-Based Technology for Glioblastoma Therapy.” This Special Issue aims to include original research articles and reviews within, but not limited to, the following research areas: design and development of nanoparticles that specifically target glioblastoma cells; strategies to enhance the ability of nanoparticles to penetrate the blood–brain barrier; engineering stimuli-responsive nanoparticles or immunomodulatory nanoparticles; nano-delivery platforms for combination therapies; imaging, diagnosis, and theranostics with nano-based systems, among others.
We look forward to receiving your contributions.
Dr. Maria João Ramalho
Dr. Joana Peixoto
Guest Editors
Manuscript Submission Information
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Keywords
- nanoparticles
- glioblastoma
- blood–brain barrier
- diagnosis
- therapy
- drug delivery
- nose-to-brain delivery
- targeted delivery
- surface modification
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