Drug Discovery: Genomic and Transcriptomic Approaches
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Biopharmaceuticals".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 3063
Special Issue Editor
Special Issue Information
Dear Colleagues,
With the development of sequencing capability and bioinformatics analytic tools, omics have become an indispensable tool in modern drug discovery. High-throughput data such as genomic, epigenetic, transcriptomic, proteomic, metabolomic, and ribosome profiling data as well as single-cell sequencing have all made significant contributions to mechanism-based drug discovery and drug repurposing. Omics data analysis can not only accelerate drug target identification and drug candidate screening but can also facilitate the characterization of side effects and predict drug resistance.
For this Special Issue, we encourage the use of omics data for drug-discovery-related exploration, aiming to provide a forum for advances in the development and application of omics-based drug-discovery strategies.
Original research articles and reviews that focus on, but are not limited to, the following topics are welcome:
- The identification or verification of drug targets and biomarkers by integrating diverse omics data;
- The identification of disease-associated screenable phenotypes based on omics data analysis;
- The prediction or refinement of drug candidates through omics data mining;
- Assessment of the potential for drug resistance or adverse drug reactions using omics data;
- Prediction of a drug's activity, toxicity, or mechanism of action through omics data analysis.
Prof. Dr. Keshen Li
Guest Editor
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Keywords
- omics
- bioinformatics
- drug discovery
- drug response
- drug target
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