Photosensitizers and Drug Delivery Systems for Photodynamic Therapy
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (25 November 2024) | Viewed by 4312
Special Issue Editor
Interests: photodynamic therapy; cancer; photosensitizer; nanoparticles; targeting; fluorescence
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Photodynamic therapy (PDT) is a light-based photochemistry process. The illumination of a photoactivatable molecule, also called photosensitizer, with visible or near-infrared light produces reactive oxygen toxic species to destroy tumor cells. This treatment modality leads to highly targeted actions because reactive oxygen species are produced only where light is applied. Light is not harmful, nor is the photoactivable molecule. Only the combination of three elements, namely a photosensitizer, oxygen, and light, is required to induce photo-oxidation reactions. PDT has proven to be a promising modality in many medical applications, including cutaneous conditions, infectious diseases, and various cancers at different stages.
The journal Pharmaceuticals invites both reviews and original articles shedding light on the challenges and opportunities of the development of innovative photosensitizers and/or drug delivery systems for PDT. Topics include selective photoactivatable molecules targeting receptors overexpressed into tumor membranes and/or on neovessels; molecules exhibiting red-shifted absorption for the better penetration of light into tissues; photobactericidal agents; theranostics; and photodiagnosis.
Dr. Céline Frochot
Guest Editor
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Keywords
- photodynamic therapy
- photosensitizers
- nanoparticles
- photo diagnosis
- targeting
- antimicrobial
- X-rays excitation
- two-photon and up-conversion
- Cherenkov
- hypoxia
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