Dental Medication

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: closed (25 November 2025) | Viewed by 1527

Special Issue Editors


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Guest Editor
Department of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13083-970, SP, Brazil
Interests: topical anesthesia; oral cavity; oral mucosa; dental anesthesia; drug delivery; mucoadhesive system; dentistry
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E-Mail Website
Guest Editor
Department of Biosciences, Piracicaba Dental School, Universidade Estadual de Campinas, Sao Paulo, Brazil
Interests: dentistry; anesthesia; local anesthesia; anxiety; pain; drug delivery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Background:
Advances in dentistry and pharmacology have been driven by new technologies and interdisciplinary research. Understanding dental medications' efficacy, safety, and mechanisms is essential, alongside developments in formulations, bioavailability, and drug interactions.

Aim and Scope:
This Special Issue seeks innovative studies on dental medications, including formulations, mechanisms of action, clinical applications, and safety. We welcome experimental research, critical reviews, computational modeling, and clinical applications, as well as advancements in drug delivery systems, digital health, and medical devices for dental pharmacology.

History:
Dental medication has evolved from ancient pain relief practices to modern anesthetics, antibiotics, and anti-inflammatory agents. Research has progressed from efficacy studies to personalized treatments and advanced formulations.

Cutting-edge Research:
Key topics include novel anesthetics, nanotechnology-based drug delivery, and bioactive biomaterials. Emerging research explores smart drug delivery systems, bioactive hydrogels, microneedles, and digital health technologies, enhancing drug administration in dentistry.

What kind of papers we are soliciting:
We invite original research, systematic reviews, and short communications on dental medications. Studies on innovative methodologies, emerging technologies, and experimental or theoretical approaches are encouraged to advance knowledge in dental pharmacology.

Prof. Dr. Michelle Franz-Montan
Dr. Camila Batista Da Silva
Guest Editors

Manuscript Submission Information

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Keywords

  • dental medication
  • local anesthetics
  • controlled drug delivery
  • nanotechnology in dentistry
  • therapeutic biomaterials
  • smart drug delivery systems
  • digital health in dental pharmacology
  • dental materials

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Published Papers (1 paper)

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Review

25 pages, 6630 KB  
Review
Clinical Studies on Topical Anesthesia in Dentistry: A Bibliometric Analysis
by Helena Carla Gonçalves dos Santos, Iago Torres Cortês de Sousa, Aylla Mesquita Pestana, Arthur Antunes Costa Bezerra, Ana Luiza Martins Lucas, Paulo Antônio Martins-Júnior and Michelle Franz-Montan
Pharmaceuticals 2025, 18(11), 1611; https://doi.org/10.3390/ph18111611 - 24 Oct 2025
Viewed by 1270
Abstract
Topical anesthesia is widely used in dentistry. However, its clinical effectiveness remains controversial. This study conducted a bibliometric analysis of the most cited clinical dentistry articles on topical anesthesia, identifying the most studied drugs, research trends, leading authors, geographic distribution, funding sources, and [...] Read more.
Topical anesthesia is widely used in dentistry. However, its clinical effectiveness remains controversial. This study conducted a bibliometric analysis of the most cited clinical dentistry articles on topical anesthesia, identifying the most studied drugs, research trends, leading authors, geographic distribution, funding sources, and study characteristics. A structured search was conducted in the Web of Science using defined descriptors and Boolean operators, with citation comparisons in Scopus and Google Scholar. The search, conducted without language or publication year restrictions, extended until October 2023. Out of 4892 articles, the 30 most cited were selected, collectively accumulating 953 citations between 1992 and 2017. Most highly cited and funded studies originated from the United States. Journals focusing on periodontics, general dentistry, and oral surgery published the majority of these articles, with lidocaine being the most studied anesthetic. Despite their widespread use, topical anesthetics have garnered relatively few citations. Our findings suggest a research preference for studies with immediate clinical impact over those focusing on pain management, particularly in the field of topical dental anesthesia. This highlights the need for further research and progress in this important field. Full article
(This article belongs to the Special Issue Dental Medication)
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