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Sensorineural Hearing Loss
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Sensorineural Hearing Loss

A special issue of Journal of Otorhinolaryngology, Hearing and Balance Medicine (ISSN 2504-463X).

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 9900

Special Issue Editor

Dr. Maoli Duan

E-Mail Website
Guest Editor
Department of Clinical Science, Technology and Intervention, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
Interests: stem cell/gene therapy; noise and drug-induced hearing loss and their protection/treatment; sudden deafness; sensorineural hearing loss; vestibular disorders and earlier intervention; diagnosis of infant and children with hearing loss
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Sensorineural hearing loss (SHL) is a very common disorder that affects more than 10% of the global population. Sensorineural hearing loss affects people of all ages, from newborn children to the elderly; SHL can delay or entirely inhibit language development in children, and in adults, it can lead to withdrawal from society—drastically decreasing quality of life. Universal newborn hearing screening, genetic research improvement, hearing aids and cochlear/auditory brainstem implantation have shed the light on the field; however, much more research and information are still required to better help SHL patients. Thus, I would like to invite you to contribute your excellent research to the Journal of Otorhinolaryngology, Hearing and Balance Medicine.

Prof. Dr. Maoli Duan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Otorhinolaryngology, Hearing and Balance Medicine is an international peer-reviewed open access semiannually journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensorineural hearing loss
  • genetic
  • hearing aids
  • cochlear implantation
  • auditory brainstem implantation
  • hair cell
  • spiral ganglion neuron

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Published Papers (2 papers)

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Research

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11 pages, 500 KiB  
Article
Delayed Speech Perception and Production after Cochlear Implantation in Bilingual Children from Non-Native Families
by Nader Nassif, Maria Grazia Barezzani and Luca Oscar Redaelli de Zinis
J. Otorhinolaryngol. Hear. Balance Med. 2021, 2(1), 4; https://doi.org/10.3390/ohbm2010004 - 13 Mar 2021
Viewed by 3973
Abstract
The aim of the study was to evaluate the outcomes of cochlear implantation (CI) in a group of immigrant deaf children living in a foreign language family, following up to 3 years of a personalized habilitation program compared to age-matched Italian CI recipients. [...] Read more.
The aim of the study was to evaluate the outcomes of cochlear implantation (CI) in a group of immigrant deaf children living in a foreign language family, following up to 3 years of a personalized habilitation program compared to age-matched Italian CI recipients. Tests of speech perception ability such as the IT-MAIS, the LiP, the CAP, and speech production such as the MUSS have been used before CI and then after 6 months, 1 year, 2 years, and 3 years. Nonparametrical tests were chosen for comparison. Eight bilingual CI recipients were included in the study and matched to 11 Italian CI recipients. The difference between chronological age at implantation, age at diagnosis, hearing age, and verbal age in the two groups of children was not significant. Comparison of the auditory perceptive and linguistic abilities between the two groups showed significant differences only in preoperative MAIS and postoperative CAP (1 to 3 years). In agreement with other studies, we achieved good performances from bilingual children with CI and our personal experience confirm the attitude of promoting bilingualism throughout the rehabilitation process. Full article
(This article belongs to the Special Issue Sensorineural Hearing Loss)
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Review

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10 pages, 2977 KiB  
Review
Standardized Methodologies to Utilize Exosome Treatment as Potential Nano Substances in Hearing Loss
by Dong Jun Park
J. Otorhinolaryngol. Hear. Balance Med. 2021, 2(2), 6; https://doi.org/10.3390/ohbm2020006 - 17 Jun 2021
Cited by 2 | Viewed by 4642
Abstract
Recently, studies on the mechanism and clinical application of stem cell-derived exosomes have increased. Although the number of patients with hearing loss is increasing, there is no ideal therapy for the recovery of auditory cells of an independent organ in humans. In this [...] Read more.
Recently, studies on the mechanism and clinical application of stem cell-derived exosomes have increased. Although the number of patients with hearing loss is increasing, there is no ideal therapy for the recovery of auditory cells of an independent organ in humans. In this review, we proposed the use of stem cell-derived exosomes for treating hearing loss and summarized the exosome research strategy platform for preclinical studies. It is necessary to select a research direction to assess direct or indirect effects on recipients based on the physiological mechanisms of exosomes that deliver useful molecules (called payloads) to recipient cells or tissues. To apply exosomes in the auditory field, researchers should select a model for assessing the toxicity to the auditory cells and analyzing their mechanisms in the recipient tissue. Such in vitro, ex vivo, and in vivo models have been designed and reported in previous studies. The analytical strategies in various models can evaluate the mechanism of exosomes based on exosome surface markers or the payload, thus helping the researchers in finding evidence regarding the efficacy of exosomes. Here, we propose three strategies for exosome application research in the auditory field. Full article
(This article belongs to the Special Issue Sensorineural Hearing Loss)
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