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New Insights in Early Growth of Premature Infants: Lifelong Health Programming

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 6095

Special Issue Editor


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Guest Editor
Department of Clinical Sciences and Community Health, University of Milan, 20122 Milano, Italy
Interests: growth pattern; body composition; premature infant; early nutrition; long-term health; obesity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Evidence suggests that early infants’ growth patterns may predict long-term health.

The effect of early nutrition and growth, and specifically the determination of the optimal time and rate of catch-up growth, could represent key factors in the comprehension of the mechanisms predisposing the risk of obesity in childhood or puberty.

Given that there is no agreement about the optimal evaluation methodologies, it is necessary to standardize such methodologies to be used in the early peri- and post-natal period which represent a key time window in terms of the lifelong health programming of preterm infants.

The dynamic evaluation of anthropometry and body composition related to early nutrition could be useful to establish certain catch-up growth patterns, possibly associated to long-term health diseases.

Pursuing this aim, this Special Issue will include manuscripts focused on the standardization of the methodologies for the early evaluation of preterm infants in order to better follow-up their early postnatal growth, body composition and early nutrition.

Dr. Paola Roggero
Guest Editor

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Keywords

  • growth pattern
  • body composition
  • premature infant
  • early nutrition
  • long-term health
  • obesity

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Published Papers (1 paper)

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13 pages, 1777 KiB  
Systematic Review
Body Composition of Infants Born with Intrauterine Growth Restriction: A Systematic Review and Meta-Analysis
by Rukman Manapurath, Barsha Gadapani and Luís Pereira-da-Silva
Nutrients 2022, 14(5), 1085; https://doi.org/10.3390/nu14051085 - 4 Mar 2022
Cited by 16 | Viewed by 5512
Abstract
Intrauterine growth restriction (IUGR) may predispose metabolic diseases in later life. Changes in fat-free mass (FFM) and fat mass (FM) may explain this metabolic risk. This review studied the effect of IUGR on body composition in early infancy. Five databases and included studies [...] Read more.
Intrauterine growth restriction (IUGR) may predispose metabolic diseases in later life. Changes in fat-free mass (FFM) and fat mass (FM) may explain this metabolic risk. This review studied the effect of IUGR on body composition in early infancy. Five databases and included studies from all countries published from 2000 until August 2021 were searched. Participants were IUGR or small-for-gestational age (SGA) infants, and the primary outcomes were FFM and FM. Eighteen studies met the inclusion criteria, of which seven were included in the meta-analysis of primary outcomes. Overall, intrauterine growth-restricted and SGA infants were lighter and shorter than normal intrauterine growth and appropriate-for-gestational age infants, respectively, from birth to the latest follow up. They had lower FFM [mean difference −429.19 (p = 0.02)] and FM [mean difference −282.9 (p < 0.001)]. The issue of whether lower FFM and FM as reasons for future metabolic risk in IUGR infants is intriguing which could be explored in further research with longer follow-up. This review, the first of its kind can be useful for developing nutrition targeted interventions for IUGR infants in future. Full article
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