Dietary Fats and Cardiometabolic Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: closed (1 October 2020) | Viewed by 12892
Special Issue Editor
Special Issue Information
Dear Colleagues,
Despite plenty of recent progress in aetiological understanding and clinical care, cardiovascular disease and type 2 diabetes remain among the top causes of death and disability worldwide. While diet has been described as a mainstay for prevention of these so-called cardiometabolic diseases, fatty acids—a major group of nutritional factors and building block of fats—have been implicated in the past as a key modifiable determinant of these conditions. However, current scientific evidence, primarily based on a large number of epidemiological and interventional studies, are still inconsistent regarding the association of fatty acids with cardiometabolic outcomes and do not entirely explain the complex pathophysiology that links fatty acids to cardiometabolic risk (or benefit). Fatty acids, depending on the level of saturation, have been grouped into “good” or “bad” fats; however, recent evidence shows that the effects of fatty acids on cardiometabolic disease are far more complex than previously viewed and could depend on the food source (e.g., meat vs. dairy products), amount of consumption and substitution by other nutrients (e.g., by carbohydrate vs. protein rich foods), and their effects could differ by sex.
This Special Issue will focus on the role of fat intake and types in the prevention and management of cardiometabolic disease and address the current controversies over the benefits of replacing saturated fatty acids with polyunsaturated fatty acids, increased consumption of fats derived from plants, interactions with different micro- and macro components of diet, the role of sex and whether fatty acids can modify the genetic predisposition to cardiometabolic disease. Other topics of interest include epidemiological and mechanistic studies examining the interaction of fatty acids with epigenetic mechanisms and microbiome in modifying the cardiometabolic risk.
Dr. Rajiv Chowdhury
Guest Editor
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Keywords
- Fatty acids
- Obesity
- Diabetes
- Cardiovascular disease
- Cardiovascular risk factors
- Women’s health
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