Nutrition Therapy for Diarrhea in Cancer and Severe Illness in Patients

Dear Colleagues,

As you know, diarrhea is a severe and common problem among cancer patients both during and after treatment for the disease, which may lead to treatment interruptions and even discontinuation. The main cause of chronic diarrhea is represented by cytotoxic agents, but targeted drugs, radiotherapy and immunotherapy can also cause this condition. Treatment-induced diarrhea can be severe and be associated with malnutrition, dehydration and electrolyte abnormalities with significant impact on quality of life and social functioning. Given the significant clinical impact of malnutrition on cancer patients, nutritional therapy should be an integral part of cancer treatment as a supportive measure. This support can lead to an improvement in the nutritional status and suppression of the gluconeogenesis associated with cancer cachexia. Nutritional support has also been shown to positively impact clinical outcomes, including improvement in tolerance to therapy, reduced hospitalizations, reduction in operative morbidity and mortality and improved sense of well-being.

In this Special Issue of Nutrients, we would like to invite experts to contribute with original research or review articles that investigate :

• the role of nutritional therapy in the management of diarrhea in cancer patients;
• the impact of cancer and its treatment on nutritional factors with emphasis on malnutrition, dietary approaches and quality of life.

Dr. Salvatore Artale
Dr. Riccardo Caccialanza
Guest Editors

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