Disease-Associated Gut Microbiota Patterns, Nutritional Factors, and Host Immunity

Dear Colleagues,

The gut microbiota play a central role in shaping host immune homeostasis and systemic inflammatory responses. Increasing evidence suggests that the distinct disease-associated patterns of gut microbiota are linked to varied human disorders, including autoimmune, inflammatory, metabolic, and neurological diseases. At the same time, dietary and nutritional factors are among the most important modulators of gut microbial composition and function.

This Special Issue will explore how nutritional factors influence disease-associated gut microbiota patterns and how these interactions affect host immune responses. Particular attention will be paid to studies investigating diet–microbiota–immune interactions, the role of dietary components and microbial metabolites in immune regulation, and the impact of nutrition-driven microbiota alterations on disease pathogenesis.

Topics of interest include dietary modulation of gut microbiota, microbiota-derived metabolites, gut barrier function, immune dysregulation associated with microbial alterations, and microbiota-targeted nutritional strategies such as probiotics, prebiotics, and dietary interventions.

Both original research articles and high-quality reviews addressing mechanistic, translational, and clinical aspects of nutrition–microbiota–immune interactions in human disease are welcome.

Dr. Zsolt Barta
Guest Editor

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