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Featured Articles on Nutrition and Obesity Management (3rd Edition)

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Obesity".

Deadline for manuscript submissions: 25 September 2025 | Viewed by 513

Special Issue Editor


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Guest Editor
Metabolic Research Lab, Clínica Universidad de Navarra—CIBEROBN—IdiSNA, 31008 Pamplona, Spain
Interests: obesity; dietary treatment; adipose tissue dysfunction; inflammation; adipokines; metabolic surgery; cardiometabolic risk improvement; body composition changes
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Special Issue Information

Dear Colleagues,

Obesity has become one of the most prevalent metabolic disorders. Excess adiposity favors the development of cardiometabolic alterations such as type 2 diabetes (T2D), cardiovascular disease, dyslipidemia, fatty liver, and cancer. In recent years, our understanding of the pathophysiology of obesity has greatly improved, and novel approaches for its treatment have emerged. However, the obesity pandemic continues without signs of abatement.

In this Special Issue, “Featured Articles on Nutrition and Obesity Management (3rd Edition)”, we welcome reviews and original articles related to any aspect of obesity management, from the traditional dietary approach (with different types of diets) to bariatric surgery, including pharmacologic treatments, with particular emphasis on recent successful combinations of drugs. We will also consider manuscripts regarding lifestyle modifications in relation to physical activity and sleep hygiene. Novel approaches such as the different modalities of intermittent fasting, including aspects relative to their effectiveness or the different physiological mechanisms involved, or the use of innovative technologies such as mobile apps or wearable devices, are very welcome. We aim to provide readers with a clear view of the pathophysiological relevance of weight loss and the improvements in cardiometabolic risk factors that occur with different therapeutic approaches, as well as the changes in body physiology and energy expenditure that drive weight regain. Original articles and reviews analyzing the clinical usefulness of predictors of treatment success and the importance of monitoring body composition in the management of patients living with obesity are also welcome.

Dr. Javier Gómez-Ambrosi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obesity
  • dietary treatment
  • lifestyle intervention
  • pharmacological treatment
  • metabolic surgery
  • intermittent fasting
  • cardiometabolic risk improvement
  • body composition changes
  • weight regain
  • predictors of treatment success
  • use of wearable devices and apps for weight loss and weight maintenance
  • novel targets
  • treatment of children and adolescents

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Published Papers (1 paper)

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Research

43 pages, 7457 KiB  
Article
Potential Association Between Atherogenic Coefficient, Prognostic Nutritional Index, and Various Obesity Indices in Diabetic Nephropathy
by Mohamed-Zakaria Assani, Marius Bogdan Novac, Anda Lorena Dijmărescu, Constantin-Cristian Văduva, Ionela Mihaela Vladu, Diana Clenciu, Adina Mitrea, Roxana-Viorela Ahrițculesei, Alexandra-Ștefania Stroe-Ionescu, Alexandru-Dan Assani, Daniel Cosmin Caragea, Mihail Virgil Boldeanu, Isabela Siloși and Lidia Boldeanu
Nutrients 2025, 17(8), 1339; https://doi.org/10.3390/nu17081339 - 14 Apr 2025
Viewed by 462
Abstract
Background/Objectives: Type 2 diabetes mellitus (T2DM), is a rapidly growing global health concern, often accompanied by chronic kidney disease (CKD) and metabolic disturbances. Obesity-related indices, such as the visceral adiposity index (VAI) and body adiposity index (BAI), have been linked to cardiovascular [...] Read more.
Background/Objectives: Type 2 diabetes mellitus (T2DM), is a rapidly growing global health concern, often accompanied by chronic kidney disease (CKD) and metabolic disturbances. Obesity-related indices, such as the visceral adiposity index (VAI) and body adiposity index (BAI), have been linked to cardiovascular and renal complications in diabetic patients. However, studies integrating both the atherogenic coefficient (AC) and prognostic nutritional index (PNI) for evaluating diabetic nephropathy (DN) remain limited. This study aimed to assess the associations of obesity-related indices with immunological and nutritional factors in patients with T2DM and prediabetes (PreDM). Methods: A retrospective, cross-sectional study was conducted over six months at a university clinical hospital in Dolj County, Romania. The study enrolled 268 newly diagnosed T2DM patients and 150 PreDM patients. Anthropometric parameters, laboratory tests, and demographic data were collected. AC and PNI were calculated using standard formulas, and statistical analyses were performed to determine their associations with metabolic and inflammatory markers. Results: Our study found that T2DM patients had significantly lower PNI values, indicating mild malnutrition, while PreDM patients maintained a normal nutritional status. AC was significantly higher in T2DM patients, correlating with lipid profile alterations and systemic inflammation. Obesity indices, particularly VAI, were significantly elevated in T2DM patients with higher AC values. Statistically significant differences in total cholesterol, low-density lipoprotein cholesterol (LDL-c), and triglycerides were observed between AC subgroups, reinforcing its role in cardiovascular risk assessment. Conclusions: The findings highlight the potential of AC and PNI as biomarkers for assessing nutritional, inflammatory, and lipemic status in diabetic patients. The significant associations between obesity-related indices, lipid profiles, and inflammation markers suggest that early assessment of these parameters may potentially aid in predicting diabetic complications. Further studies are needed to explore the clinical utility of AC and PNI in managing T2DM and CKD progression. Future research should investigate how the lipidic spectrum alters the progression of DN across various patient groups with diabetes and prediabetes Full article
(This article belongs to the Special Issue Featured Articles on Nutrition and Obesity Management (3rd Edition))
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