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Nutrients
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Addressing Malnutrition in the Aging Population
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Addressing Malnutrition in the Aging Population

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 5 December 2025 | Viewed by 772

Special Issue Editor

Dr. Patrizia D'Amelio

E-Mail Website
Guest Editor
Service of Geriatric Medicine & Geriatric Rehabilitation, Department of Medicine, University of Lausanne Hospital (CHUV), 1011 Lausanne, Switzerland
Interests: osteoporosis; sarcopenia; dementia; aging; cellular senescence; inflammaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Malnutrition profoundly impacts healthy aging and is an often underestimated, critical healthcare concern. Aging often brings physiological changes like reduced appetite, dental issues, and chronic diseases, which can limit nutritional intake. Psychological factors such as depression and social isolation also contribute to the risk of malnutrition.

Malnutrition is closely linked to frailty, muscle loss (sarcopenia), weakened immunity, and delayed recovery from illness. It increases the likelihood of falls, hospitalizations, and higher mortality rates. Early identification and management are essential to prevent these outcomes and improve quality of life.

A multidisciplinary approach is vital, involving regular nutritional screening, personalized diet plans, and social support from caregivers and healthcare providers. Promoting better nutrition in older adults helps reduce healthcare costs and enhances their physical and emotional health. Addressing malnutrition is key to ensuring healthy aging and maintaining independence.

Dr. Patrizia D'Amelio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • older adults
  • malnutrition
  • healthy aging
  • frailty
  • sarcopenia
  • nutritional screening

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Published Papers (2 papers)

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Research

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14 pages, 436 KiB  
Article
Validation and Reliability of the Polish Version of the Eating Assessment Tool-10 Questionnaire
by Barbara Jamroz, Magdalena Milewska, Aleksandra Ostrowska, Joanna Chmielewska-Walczak, Mariusz Panczyk and Dorota Szostak-Wegierek
Nutrients 2025, 17(8), 1291; https://doi.org/10.3390/nu17081291 - 8 Apr 2025
Viewed by 311
Abstract
Introduction: Early identification of patients at risk of dysphagia is of paramount importance. To date, no dysphagia screening questionnaire has been validated and translated into Polish that can be widely used in a multidisciplinary setting. Our study aimed to validate and adapt the [...] Read more.
Introduction: Early identification of patients at risk of dysphagia is of paramount importance. To date, no dysphagia screening questionnaire has been validated and translated into Polish that can be widely used in a multidisciplinary setting. Our study aimed to validate and adapt the Polish version of the Eating Assessment Tool-10 questionnaire (EAT-10). Materials and Methods: The EAT-10 questionnaire was translated into Polish using a formal forward–backward translation method. The Polish EAT-10 was administered to 109 patients with different dysphagia etiologies and 24 control subjects. Internal consistency, unidimensionality, test–retest reliability and external validity against the Visual Analog Scale (VAS), and Flexible Endoscopic Evaluation of Swallowing (FEES) were performed. Results: The EAT-10PL demonstrated excellent internal consistency (Cronbach’s α = 0.958) and confirmed unidimensionality. We found a strong correlation between EAT-10PL with the Visual Analog Scale (VAS) (rs = 0.94, p < 0.001) and a weaker correlation with the PAS (rs = 0.55, p < 0.001). We reported a sensitivity of 79.5% and specificity at the level of 60.0%, using ≥3 as a cut-off point. The statistically chosen cutoff point for PAS ≥ 2 and EAT-10 ≥ 6 indicated optimal specificity (70.0%) and sensitivity (79.5%) of measurements performed using EAT-10PL. The EAT-10PL questionnaire demonstrates high discriminatory ability relative to the control group (F(4, 104) = 16.219, p < 0.001, η2 = 0.38 [95%CI: 0.22–0.48]). Conclusions: The Polish EAT-10 is a valid and reliable, self-administered questionnaire for dysphagic patient identification. The Polish EAT-10 ≥ 3 can be considered abnormal; however, it seems that EAT-10PL is not appropriate for patients with dysphagia and a chronic cough background, and further research is required. Full article
(This article belongs to the Special Issue Addressing Malnutrition in the Aging Population)
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15 pages, 2092 KiB  
Systematic Review
Non-Severe Hypophosphatemia in Older Patients: A Systematic Review
by Luca Barbarossa, Martina Zandonà, Maria Luisa Garo, Ribal Bou Mjahed and Patrizia D’Amelio
Nutrients 2025, 17(8), 1354; https://doi.org/10.3390/nu17081354 - 16 Apr 2025
Viewed by 334
Abstract
Background/Objectives: Phosphorus plays a fundamental role in cellular and extracellular metabolism, contributing to nucleic acid synthesis, enzymatic activity, neurologic function, and skeletal mineralization. Despite its significance, non-severe hypophosphatemia (HP) remains largely asymptomatic and underdiagnosed, with limited data on its prevalence in the general [...] Read more.
Background/Objectives: Phosphorus plays a fundamental role in cellular and extracellular metabolism, contributing to nucleic acid synthesis, enzymatic activity, neurologic function, and skeletal mineralization. Despite its significance, non-severe hypophosphatemia (HP) remains largely asymptomatic and underdiagnosed, with limited data on its prevalence in the general population. Most studies focus on specific subgroups, such as critically ill or dialysis patients, while the impact of mild HP in older adults, a potentially vulnerable demographic, is not well understood. The objective of this systematic review is to investigate the prevalence and clinical implications of non-severe HP in older adults. Methods: The study followed PRISMA guidelines to assess HP in patients aged ≥ 65 years without critical illnesses or genetic disorders. A systematic search was conducted in PubMed, Web of Science, and Scopus (March 2024). Eligible studies included RCTs and prospective/retrospective studies, excluding cancer-related studies or insufficient phosphate data. Results: We identified 1350 articles, with 26 meeting eligibility criteria. Ultimately, eight studies involving 26,548 patients were included, with an HP prevalence of 12.5%. Studies reveal a higher prevalence of HP in frail individuals, particularly those with increased frailty scores, and an association between HP and cognitive decline, depressed mood, falls, and chronic comorbidities. HP was also prevalent in infectious diseases, especially bacterial pneumonia, with longer hospital stays and increased mortality rates. Malnutrition was significantly more common in HP patients, characterized by weight loss and poor nutritional status. Furthermore, HP increased fall risk during hospitalization and worsened outcomes after coronary artery bypass graft surgery, including higher mortality and graft failure rates, underscoring its clinical importance. Discussion: This review identified that non-severe hypophosphatemia (HP) is associated with conditions such as frailty, cognitive decline, and an increased risk of falls. The evidence suggests that low phosphate levels may negatively impact health, increasing mortality and the risk of adverse clinical outcomes. Despite limitations in diagnostic criteria and sample variability, the findings indicate that HP can be a useful marker for identifying patients at risk of health deterioration. Further research is needed to clearly define the management and treatment of HP in this vulnerable population. Full article
(This article belongs to the Special Issue Addressing Malnutrition in the Aging Population)
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