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Diet, Nutritional Intervention and Quality of Life in Food-Induced Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 738

Special Issue Editor


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Guest Editor
Pediatric Gastroenterology and Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy
Interests: celiac disease; food allergy; food intolerance; gluten disorder; pediatric gastroenterology; quality of life; small bowel disease; villous atrophy

Special Issue Information

Dear Colleagues,

Food-induced diseases—including food allergies, intolerances, celiac disease, and other immune-mediated or metabolic conditions—are increasingly recognized as major public health concerns with profound impacts on individual well-being and healthcare systems worldwide. Diet plays a central role in both the pathogenesis and management of these disorders, with nutritional interventions often serving as the primary therapy. However, while dietary restrictions can be life-saving or symptom-relieving, they may also carry unintended consequences, including nutritional deficiencies, diminished quality of life, and psychosocial and economic burdens.

We invite original research and reviews that examine the complex interplay between dietary management, nutritional adequacy, and quality of life in individuals affected by food-induced diseases, e.g.:

  • the effectiveness and safety of elimination diets;
  • strategies to optimize nutritional status;
  • psychological and social implications of dietary restrictions;
  • emerging biomarkers for dietary response and disease monitoring;
  • novel dietary or microbiome-based therapies.

By bringing together multidisciplinary perspectives from nutrition science, gastroenterology, immunology, psychology, and public health, this Special Issue seeks to advance evidence-based, patient-centered approaches to managing food-induced conditions, ultimately aiming to improve both clinical outcomes and lived experiences.

Dr. Marco Crocco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food-induced diseases
  • dietary management
  • nutritional intervention
  • quality of life
  • food allergies
  • celiac disease
  • elimination diets

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Published Papers (1 paper)

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Review

26 pages, 617 KB  
Review
Decoding Picky Eating in Children: A Temporary Phase or a Hidden Health Concern?
by Dorina Pjetraj, Amarildo Pjetraj, Dalia Sayed, Michele Severini, Ludovica Falcioni, Lucia Emanuela Svarca, Simona Gatti and Maria Elena Lionetti
Nutrients 2025, 17(24), 3884; https://doi.org/10.3390/nu17243884 - 12 Dec 2025
Viewed by 567
Abstract
Background: Picky eating (PE), also termed food selectivity, is one of the most common feeding concerns in childhood. Although often a transient developmental stage, persistent or severe selectivity may lead to nutritional deficiencies, growth impairment, and psychosocial consequences. Methods: This narrative [...] Read more.
Background: Picky eating (PE), also termed food selectivity, is one of the most common feeding concerns in childhood. Although often a transient developmental stage, persistent or severe selectivity may lead to nutritional deficiencies, growth impairment, and psychosocial consequences. Methods: This narrative review is based on literature searches conducted in April 2025 across PubMed, Web of Science, Embase, Medline, and Google Scholar. Articles published between 2015 and 2025 were included if they addressed the epidemiology, etiology, assessment, or management of PE in children aged 0–18 years. Additional seminal references predating this period were also considered. Results: Prevalence estimates of PE vary widely (13–50%), with peak incidence between ages two and six. Contributing factors include genetic predisposition, sensory sensitivities, temperament, family feeding practices, environmental influences, and adverse feeding experiences. Distinction from avoidant/restrictive food intake disorder (ARFID) and pediatric feeding disorder (PFD) is essential, as these conditions carry greater risk of nutritional and psychosocial impairment. Assessment relies on caregiver-report instruments, clinical observation, growth monitoring, and targeted nutritional evaluation. Effective management integrates parental education, responsive feeding strategies, repeated exposure to novel foods, and, when indicated, nutritional supplementation or referral to multidisciplinary teams. Sensory-based therapies, behavioral interventions, and psychoeducational programs show particular benefit in persistent cases. Conclusions: While most children outgrow PE without adverse outcomes, a subset remains at risk of long-term nutritional compromise and psychosocial difficulties. Early recognition, family-centered guidance, and evidence-based interventions are essential. Future research should refine diagnostic criteria, develop culturally sensitive assessment tools, and evaluate innovative therapies to improve outcomes. Full article
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