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Bioactive Compounds in Functional Foods: Mechanisms, Efficacy, and Future Directions

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 5 November 2026 | Viewed by 218

Special Issue Editors

Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun 130021, China
Interests: nutritional epidemiology; multi-omics; gut microbes; vitamins; phytochemicals
Special Issues, Collections and Topics in MDPI journals
Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun 130021, China
Interests: phytochemicals; cancer nutrition; nutrient; disease nutrition; radiation injury

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Guest Editor
School of Public Health, Qingdao University, Qingdao 266071, China
Interests: nutrition; bone metabolism; gut microbiota; energy metabolism; functional foods

Special Issue Information

Dear Colleagues,

Functional foods have attracted growing attention for their potential to promote health and reduce the risk of chronic diseases beyond basic nutrition. A wide range of bioactive compounds derived from natural food sources—including polyphenols, peptides, polysaccharides, and other metabolites—have been shown to exert diverse biological activities, such as antioxidant, anti-inflammatory, and metabolic regulatory effects. With advances in analytical and biological technologies, increasing efforts have been devoted to elucidating the mechanisms and health effects of these compounds.

This Special Issue aims to provide updated insights into the identification, mechanisms, and health implications of bioactive compounds in functional foods. A better understanding of these complex relationships will help translate scientific findings into practical nutritional strategies and support the development of functional foods.

We invite original research articles and reviews that explore the roles of bioactive compounds in functional foods. Topics include, but are not limited to, their molecular mechanisms and biological functions, interactions with gut microbiota, roles in metabolic regulation and chronic disease prevention, and emerging analytical and multi-omics approaches that advance the understanding of their efficacy and health-promoting effects. Studies based exclusively on database mining or computational prediction without experimental, clinical, or population-based evidence are generally not considered within the scope of this Special Issue, whereas studies involving human cohort data or epidemiological analyses are welcome.

Dr. Weiwei Cui
Dr. Fang Fang
Dr. Tianlin Gao
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive compounds
  • functional foods
  • bioactive peptides
  • vitamins
  • polyphenols
  • gut microbiota
  • mechanisms
  • nutritional efficacy
  • precision nutrition
  • disease prevention

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Published Papers

This special issue is now open for submission.
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